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- Title
Carbamate Series of Juvenoids: Variation of the O-alkyl substituent.
- Authors
Wimmer, Zdenêk; S̆aman, David; Nêmec, Václav; Francke, Wittko
- Abstract
By changing the O-alkyl substituents of the carbamate moiety of alkyl N-{2-{4-[(2-oxocyclohexyl)methyl]phenoxy}ethyl}carbamates and subsequent transformation of the oxo group in the cyclohexyl substituent, the juvenoids 1-20 were synthesized ( Scheme). The methyl ( 1-4), propyl ( 9-12), isopropyl ( 13-16), and prop-2-ynylcarbamates ( 17-20) were subjected to biological screening on several non-related insect species ( Tenebrio molitor, Galleria mellonella, Dysdercus cingulatus, and Pyrrhocoris apterus). Some of the juvenoids showed high biological activity and excellent selectivity with respect to target insect species ( Table 2).
- Publication
Helvetica Chimica Acta, 1994, Vol 77, Issue 2, p561
- ISSN
0018-019X
- Publication type
Article
- DOI
10.1002/hlca.19940770218