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- Title
Histopathological Changes Within the Testis Caused by Allyl Chloride Exposure in Mice.
- Authors
Zhao, M.; Omura, M.; Tokunaga, S.; Romero, Y.; Inoue, N.
- Abstract
The article presents a study on histopathological changes within the testis caused by allyl chloride exposure in mice. Allyl chloride (AC) is used in the production of epoxy resins, glycerol, sodium allylsulfonate, and other chemicals. Polyneuropathy and liver dysfunction have been reported in workers exposed to AC and these adverse effects were reproduced in animal experiments. To begin the study, one hundred male ICR mice were purchased at seven weeks of age and were acclimatized to our animal facility for two weeks. Mice were then housed five per cage in a specific pathogen -free room. The testis was fixed in Bouin's solution, embedded in paraffin, thinly sectioned, and then stained with periodic acid Schiff reagent and hematoxylin.
- Subjects
RESEARCH; ALLYL chloride; EPOXY resins; GLYCERIN; MICE; TESTIS; SCROTUM; CHLORIDES; ALKALI metals
- Publication
Bulletin of Environmental Contamination & Toxicology, 1998, Vol 60, Issue 3, p494
- ISSN
0007-4861
- Publication type
Article
- DOI
10.1007/s001289900652