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- Title
Acute callosal disconnection syndrome as an initial manifestation of neuromyelitis optica spectrum disorders.
- Authors
Kobayashi, Junpei; Kuroda, Hiroshi; Ezura, Michinori; Sugeno, Naoto; Shibui, Aya; Takahashi, Toshiyuki; Misu, Tatsuro; Fujihara, Kazuo; Mori, Etsuro; Aoki, Masashi
- Abstract
We present a 76-year-old ambidextrous man with acute callosal disconnection syndrome accompanied by acquired stuttering and right hemiparesis. Brain magnetic resonance imaging showed edematous pancallosal lesions and a spotty lesion in the left precentral gyrus. We diagnosed him as having neuromyelitis optica spectrum disorders according to the seropositivity for anti-aquaporin-4 antibody. Callosal disconnection syndrome presented unique laterality as a result of ambidexterity, and was outstanding even during the acute attack as a result of massive and selective corpus callosum involvement. Measurement of anti-aquaporin-4 antibody can be useful for differential diagnosis of patients presenting acute callosal disconnection syndrome.
- Subjects
CORPUS callosum abnormalities; NEUROMYELITIS optica; STUTTERING; MULTIPLE sclerosis; NEUROPSYCHIATRY; AQUAPORINS
- Publication
Neurology & Clinical Neuroscience, 2015, Vol 3, Issue 4, p137
- ISSN
2049-4173
- Publication type
Article
- DOI
10.1111/ncn3.164