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- Title
RESPONSE.
- Authors
Landi, Maria Teresa; Kanetsky, Peter; Goldstein, Alisa; Pfeiffer, Ruth
- Abstract
The article presents a response on a comment by M.C. Fargnoli and colleagues about the association of melanocortin-1 receptor gene variants with melanoma risk. The author explained that the different estimates for melanoma risk and pigmentation among subjects carrying any variant or nonred hair color variants could be due to sample variability or differences in the categorization scheme used for pigmentation characteristics. Each individual red hair color variant as presented by Fargnoli and colleagues was analyzed by the author. According to the author, the results observed by Fargnoli and colleagues were remarkably similar to theirs and that they strongly support the evidence of an important role of MC1R in the pathogenesis of melanoma.
- Subjects
MELANOMA; DISEASE risk factors; POPULATION; MEDICAL research; NEUROENDOCRINE tumors; CANCER
- Publication
JNCI: Journal of the National Cancer Institute, 2006, Vol 98, Issue 2, p145
- ISSN
0027-8874
- Publication type
Article
- DOI
10.1093/jnci/djj026