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- Title
Microfluidic Autologous Serum Eye-Drops Preparation as a Potential Dry Eye Treatment.
- Authors
Takao Yasui; Jumpei Morikawa; Noritada Kaji; Manabu Tokeshi; Kazuo Tsubota; Yoshinobu Baba
- Abstract
Dry eye is a problem in tearing quality and/or quantity and it afflicts millions of persons worldwide. An autologous serum eye-drop is a good candidate for dry eye treatment; however, the eye-drop preparation procedures take a long time and are relatively troublesome. Here we use spiral microchannels to demonstrate a strategy for the preparation of autologous serum eye-drops, which provide benefits for all dry eye patients; 100% and 90% removal efficiencies are achieved for 10 μm microbeads and whole human blood cells, respectively. Since our strategy allows researchers to integrate other functional microchannels into one device, such a microfluidic device will be able to offer a new one-step preparation system for autologous serum eye-drops.
- Subjects
EYE drops; TREATMENT of dry eye syndromes; MICROFLUIDICS
- Publication
Micromachines, 2016, Vol 7, Issue 7, p113
- ISSN
2072-666X
- Publication type
Article
- DOI
10.3390/mi7070113