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Molecular pathogenesis of multiple myeloma: basic and clinical updates.
Published in:
International Journal of Hematology, 2013, v. 97, n. 3, p. 313, doi. 10.1007/s12185-013-1291-2
By:
- Chesi, Marta;
- Bergsagel, P.
Publication type:
Article
Identification of kinetin riboside as a repressor of CCND1 and CCND2 with preclinical antimyeloma activity.
Published in:
2008
By:
- Tiedemann, Rodger E.;
- Xinliang Mao;
- Chang-Xin Shi;
- Yuan Xiao Zhu;
- Palmer, Stephen E.;
- Sebag, Michael;
- Marler, Ron;
- Chesi, Marta;
- Fonseca, Rafael;
- Bergsagel, P. Leif;
- Schimmer, Aaron D.;
- Stewart, A. Keith;
- Mao, Xinliang;
- Shi, Chang-Xin;
- Zhu, Yuan Xiao
Publication type:
journal article
Longitudinal single-cell analysis of a myeloma mouse model identifies subclonal molecular programs associated with progression.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26598-w
By:
- Croucher, Danielle C.;
- Richards, Laura M.;
- Tsofack, Serges P.;
- Waller, Daniel;
- Li, Zhihua;
- Wei, Ellen Nong;
- Huang, Xian Fang;
- Chesi, Marta;
- Bergsagel, P. Leif;
- Sebag, Michael;
- Pugh, Trevor J.;
- Trudel, Suzanne
Publication type:
Article
Transcriptional repression by the HDAC4-RelB-p52 complex regulates multiple myeloma survival and growth.
Published in:
Scientific Reports, 2015, p. 8428, doi. 10.1038/ncomms9428
By:
- Vallabhapurapu, Subrahmanya D.;
- Noothi, Sunil K.;
- Pullum, Derek A.;
- Lawrie, Charles H.;
- Pallapati, Rachel;
- Potluri, Veena;
- Kuntzen, Christian;
- Khan, Sohaib;
- Plas, David R.;
- Orlowski, Robert Z.;
- Chesi, Marta;
- Kuehl, W. Michael;
- Bergsagel, P. Leif;
- Karin, Michael;
- Vallabhapurapu, Sivakumar
Publication type:
Article
Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07305-8
By:
- Calcinotto, Arianna;
- Brevi, Arianna;
- Chesi, Marta;
- Ferrarese, Roberto;
- Garcia Perez, Laura;
- Grioni, Matteo;
- Kumar, Shaji;
- Garbitt, Victoria M.;
- Sharik, Meaghen E.;
- Henderson, Kimberly J.;
- Tonon, Giovanni;
- Tomura, Michio;
- Miwa, Yoshihiro;
- Esplugues, Enric;
- Flavell, Richard A.;
- Huber, Samuel;
- Canducci, Filippo;
- Rajkumar, Vincent S.;
- Bergsagel, P. Leif;
- Bellone, Matteo
Publication type:
Article
High-Resolution Genomic Analysis in Waldenström's Macroglobulinemia Identifies Disease-Specific and Common Abnormalities with Marginal Zone Lymphomas.
Published in:
Clinical Lymphoma & Myeloma, 2009, v. 9, n. 1, p. 39
By:
- Braggio, Esteban;
- Keats, Jonathan J.;
- Leleu, Xavier;
- Wier, Scott Van;
- Jimenez-Zepeda, Victor Hugo;
- Schop, Roelandt F. J.;
- Chesi, Marta;
- Barrett, Michael;
- Stewart, Alexander Keith;
- Dogan, Ahmet;
- Bergsagel, Peter Leif;
- Ghobrial, Irene M.;
- Fonseca, Rafael
Publication type:
Article
Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy.
Published in:
EMBO Journal, 2015, v. 34, n. 9, p. 1214, doi. 10.15252/embj.201489920
By:
- Desantis, Agata;
- Bruno, Tiziana;
- Catena, Valeria;
- De Nicola, Francesca;
- Goeman, Frauke;
- Iezzi, Simona;
- Sorino, Cristina;
- Ponzoni, Maurilio;
- Bossi, Gianluca;
- Federico, Vincenzo;
- La Rosa, Francesca;
- Ricciardi, Maria Rosaria;
- Lesma, Elena;
- De Meo, Paolo D'Onorio;
- Castrignanò, Tiziana;
- Petrucci, Maria Teresa;
- Pisani, Francesco;
- Chesi, Marta;
- Bergsagel, P Leif;
- Floridi, Aristide
Publication type:
Article
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites.
Published in:
Nature, 2011, v. 470, n. 7332, p. 124, doi. 10.1038/nature09658
By:
- Huadong Pei;
- Lindsey Zhang;
- Kuntian Luo;
- Yuxin Qin;
- Chesi, Marta;
- Fei, Frances;
- Bergsagel, P. Leif;
- Liewei Wang;
- Zhongsheng You;
- Zhenkun Lou
Publication type:
Article
Bone marrow transplantation generates T cell-dependent control of myeloma in mice.
Published in:
2019
By:
- Vuckovic, Slavica;
- Minnie, Simone A.;
- Smith, David;
- Gartlan, Kate H.;
- Watkins, Thomas S.;
- Markey, Kate A.;
- Mukhopadhyay, Pamela;
- Guillerey, Camille;
- Kuns, Rachel D.;
- Locke, Kelly R.;
- Pritchard, Antonia L.;
- Johansson, Peter A.;
- Varelias, Antiopi;
- Ping Zhang;
- Huntington, Nicholas D.;
- Waddell, Nicola;
- Chesi, Marta;
- Miles, John J.;
- Smyth, Mark J.;
- Hill, Geoffrey R.
Publication type:
journal article
Immunosurveillance and therapy of multiple myeloma are CD226 dependent.
Published in:
2015
By:
- Guillerey, Camille;
- Ferrari de Andrade, Lucas;
- Vuckovic, Slavica;
- Miles, Kim;
- Ngiow, Shin Foong;
- Yong, Michelle C R;
- Teng, Michele W L;
- Colonna, Marco;
- Ritchie, David S;
- Chesi, Martha;
- Bergsagel, P Leif;
- Hill, Geoffrey R;
- Smyth, Mark J;
- Martinet, Ludovic;
- Chesi, Marta
Publication type:
journal article
TIM-3<sup>+</sup> CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies.
Published in:
Science Immunology, 2024, v. 9, n. 94, p. 1, doi. 10.1126/sciimmunol.adg1094
By:
- Minnie, Simone A.;
- Waltner, Olivia G.;
- Zhang, Ping;
- Takahashi, Shuichiro;
- Nemychenkov, Nicole S.;
- Ensbey, Kathleen S.;
- Schmidt, Christine R.;
- Legg, Samuel R. W.;
- Comstock, Melissa;
- Boiko, Julie R.;
- Nelson, Ethan;
- Bhise, Shruti S.;
- Wilkens, Alec B.;
- Koyama, Motoko;
- Dhodapkar, Madhav V.;
- Chesi, Marta;
- Riddell, Stanley R.;
- Green, Damian J.;
- Spencer, Andrew;
- Furlan, Scott N.
Publication type:
Article
Transcriptional repression by the HDAC4-RelB-p52 complex regulates multiple myeloma survival and growth.
Published in:
Nature Communications, 2015, v. 6, n. 10, p. 8428, doi. 10.1038/ncomms9428
By:
- Vallabhapurapu, Subrahmanya D.;
- Noothi, Sunil K.;
- Pullum, Derek A.;
- Lawrie, Charles H.;
- Pallapati, Rachel;
- Potluri, Veena;
- Kuntzen, Christian;
- Khan, Sohaib;
- Plas, David R.;
- Orlowski, Robert Z.;
- Chesi, Marta;
- Kuehl, W. Michael;
- Bergsagel, P. Leif;
- Karin, Michael;
- Vallabhapurapu, Sivakumar
Publication type:
Article
P-099: Perturbation of CDK7 and super-enhancer driven transcriptional programs synergistically halts multiple myeloma cell proliferation.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S93, doi. 10.1016/S2152-2650(21)02233-3
By:
- Yao Yao;
- Park, Woojun D.;
- Morelli, Eugenio;
- Samur, Mehmet K.;
- Kwiatkowski, Nicholas;
- Yan Xu;
- Nabet, Behnam;
- Chakraborty, Chandraditya;
- Chesi, Marta;
- Gray, Nathaniel;
- Young, Rick;
- Anderson, Kenneth;
- Lin, Charles;
- Munshi, Nikhil C.;
- Fulciniti, Mariateresa
Publication type:
Article
Mass Cytometry reveals unique phenotypic patterns associated with subclonal diversity and outcomes in multiple myeloma.
Published in:
Blood Cancer Journal, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41408-023-00851-5
By:
- Baughn, Linda B.;
- Jessen, Erik;
- Sharma, Neeraj;
- Tang, Hongwei;
- Smadbeck, James B.;
- Long, Mark D.;
- Pearce, Kathryn;
- Smith, Matthew;
- Dasari, Surendra;
- Sachs, Zohar;
- Linden, Michael A.;
- Cook, Joselle;
- Keith Stewart, A.;
- Chesi, Marta;
- Mitra, Amit;
- Leif Bergsagel, P.;
- Van Ness, Brian;
- Kumar, Shaji K.
Publication type:
Article
Mass Cytometry reveals unique phenotypic patterns associated with subclonal diversity and outcomes in multiple myeloma.
Published in:
Blood Cancer Journal, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41408-023-00851-5
By:
- Baughn, Linda B.;
- Jessen, Erik;
- Sharma, Neeraj;
- Tang, Hongwei;
- Smadbeck, James B.;
- Long, Mark D.;
- Pearce, Kathryn;
- Smith, Matthew;
- Dasari, Surendra;
- Sachs, Zohar;
- Linden, Michael A.;
- Cook, Joselle;
- Keith Stewart, A.;
- Chesi, Marta;
- Mitra, Amit;
- Leif Bergsagel, P.;
- Van Ness, Brian;
- Kumar, Shaji K.
Publication type:
Article
V. Molecular classification and risk stratification of myeloma.
Published in:
Hematological Oncology, 2013, v. 31, p. 38, doi. 10.1002/hon.2065
By:
- Bergsagel, P. Leif;
- Chesi, Marta
Publication type:
Article
Osteopontin dysregulation and lytic bone lesions in multiple myeloma.
Published in:
Hematological Oncology, 2007, v. 25, n. 1, p. 16, doi. 10.1002/hon.803
By:
- Robbiani, Davide F.;
- Colon, Kaity;
- Ely, Sarah;
- Ely, Scott;
- Chesi, Marta;
- Bergsagel, P. Leif
Publication type:
Article
Phase II trial of nab-paclitaxel in patients with relapsed or refractory multiple myeloma.
Published in:
American Journal of Hematology, 2016, v. 91, n. 12, p. E504, doi. 10.1002/ajh.24548
By:
- Jain, Tania;
- Dueck, Amylou C.;
- Kosiorek, Heidi e.;
- Ginos, Brenda F.;
- Mayo, Angela;
- Reeder, Craig B.;
- Chesi, Marta;
- Mikhael, Joseph;
- Keith Stewart, A.;
- Leif Bergsagel, P.;
- Fonseca, Rafael
Publication type:
Article
Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair.
Published in:
Journal of Hematology & Oncology, 2017, v. 10, p. 1, doi. 10.1186/s13045-017-0495-y
By:
- López-Iglesias, Ana-Alicia;
- Herrero, Ana B.;
- Chesi, Marta;
- San-Segundo, Laura;
- González-Méndez, Lorena;
- Hernández-García, Susana;
- Misiewicz-Krzeminska, Irena;
- Quwaider, Dalia;
- Martín-Sánchez, Montserrat;
- Primo, Daniel;
- Paíno, Teresa;
- Bergsagel, P. Leif;
- Mehrling, Thomas;
- González-Díaz, Marcos;
- San-Miguel, Jesús F.;
- Mateos, María-Victoria;
- Gutiérrez, Norma C.;
- Garayoa, Mercedes;
- Ocio, Enrique M.
Publication type:
Article
Role of Pirh2 in Mediating the Regulation of p53 and c-Myc.
Published in:
PLoS Genetics, 2011, v. 7, n. 11, p. 1, doi. 10.1371/journal.pgen.1002360
By:
- Hakem, Anne;
- Bohgaki, Miyuki;
- Lemmers, Bénédicte;
- Tai, Elisabeth;
- Salmena, Leonardo;
- Matysiak-Zablocki, Elzbieta;
- Yong-Sam Jung;
- Karaskova, Jana;
- Kaustov, Lilia;
- Duan, Shili;
- Madore, Jason;
- Boutros, Paul;
- Yi Sheng;
- Chesi, Marta;
- Bergsagel, P. Leif;
- Perez-Ordonez, Bayardo;
- Mes-Masson, Anne-Marie;
- Penn, Linda;
- Squire, Jeremy;
- Xinbin Chen
Publication type:
Article
Single-Cell Proteomics and Tumor RNAseq Identify Novel Pathways Associated With Clofazimine Sensitivity in PI- and IMiD- Resistant Myeloma, and Putative Stem-Like Cells.
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.842200
By:
- Kumar, Harish;
- Mazumder, Suman;
- Sharma, Neeraj;
- Chakravarti, Sayak;
- Long, Mark D.;
- Meurice, Nathalie;
- Petit, Joachim;
- Liu, Song;
- Chesi, Marta;
- Sanyal, Sabyasachi;
- Stewart, A. Keith;
- Kumar, Shaji;
- Bergsagel, Leif;
- Rajkumar, S. Vincent;
- Baughn, Linda B.;
- Van Ness, Brian G.;
- Mitra, Amit Kumar
Publication type:
Article

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