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α-Synuclein-induced dysregulation of neuronal activity contributes to murine dopamine neuron vulnerability.
- Published in:
- NPJ Parkinson's Disease, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41531-021-00210-w
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- Article
Il-10 signaling reduces survival in mouse models of synucleinopathy.
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- NPJ Parkinson's Disease, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41531-021-00169-8
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- Article
Reassessment of Neuronal Tau Distribution in Adult Human Brain and Implications for Tau Pathobiology.
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- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01394-9
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- Article
Impact of APOE genotype on prion-type propagation of tauopathy.
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- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01359-y
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- Publication type:
- Article
Disease-, region- and cell type specific diversity of α-synuclein carboxy terminal truncations in synucleinopathies.
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- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01242-2
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- Article
Robust α-synuclein pathology in select brainstem neuronal populations is a potential instigator of multiple system atrophy.
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- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01173-y
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- Article
Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer's disease and other tauopathies.
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- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00967-w
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- Article
Tau K321/K353 pseudoacetylation within KXGS motifs regulates tau–microtubule interactions and inhibits aggregation.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-96627-7
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- Article
Augmentation of phenotype in a transgenic Parkinson mouse heterozygous for a Gaucher mutation.
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- Brain: A Journal of Neurology, 2014, v. 137, n. 12, p. 3235, doi. 10.1093/brain/awu291
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- Article
Exploring the pathologic synergy between amyloid β and tau: Molecular and cell biology/tau.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043477
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- Article
O4‐01‐05: COMPARATIVE PRIONOID AND STRAIN PROPERTIES OF TAU AND SYNUCLEIN.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1230, doi. 10.1016/j.jalz.2019.06.4744
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- Article
P3‐091: MODELING TAUOPATHY USING AAV‐MEDIATED SOMATIC BRAIN TRANSGENESIS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1100, doi. 10.1016/j.jalz.2018.06.1447
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- Article
Tau Lysine Pseudomethylation Regulates Microtubule Binding and Enhances Prion-like Tau Aggregation.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 9, p. 8286, doi. 10.3390/ijms24098286
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- Article
MhcII Regulates Transmission of α-Synuclein-Seeded Pathology in Mice.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8175, doi. 10.3390/ijms23158175
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- Article
Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration.
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- Journal of Clinical Investigation, 2013, v. 123, n. 12, p. 5389, doi. 10.1172/JCI70317
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- Article
Thinking laterally about neurodegenerative proteinopathies.
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- 2013
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- Publication type:
- journal article
Thinking laterally about neurodegenerative proteinopathies.
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- Journal of Clinical Investigation, 2013, v. 123, n. 5, p. 1847, doi. 10.1172/JCI66029
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- Article
Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice.
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- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03373-1
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- Article
TARGETING TAU AGGREGATION IN BRAIN SLICE CULTURE MODELS OF TAUOPATHIES.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1294, doi. 10.1016/j.jalz.2017.06.1959
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- Article
IL-10 modifies disease progression and pathology in a mouse model of alpha synucleinopathy.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P182, doi. 10.1016/j.jalz.2015.07.154
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- Article
Cell-to-cell transmission of synucleinopathy.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P258, doi. 10.1016/j.jalz.2015.07.327
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- Publication type:
- Article
Degradative organelles containing mislocalized α- and β-synuclein proliferate in presenilin-1 null neurons.
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- Journal of Cell Biology, 2004, v. 165, n. 3, p. 335, doi. 10.1083/jcb.200403061
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- Publication type:
- Article
Novel antibodies to phosphorylated α-synuclein serine 129 and NFL serine 473 demonstrate the close molecular homology of these epitopes.
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- Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0357-9
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- Publication type:
- Article
Physiologically relevant factors influence tau phosphorylation by leucine-rich repeat kinase 2.
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- Journal of Neuroscience Research, 2015, v. 93, n. 10, p. 1567, doi. 10.1002/jnr.23614
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- Article
Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants.
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- Journal of Neuroscience Research, 2012, v. 90, n. 12, p. 2306, doi. 10.1002/jnr.23112
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- Article
Characterization of kinases involved in the phosphorylation of aggregated α-synuclein.
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- Journal of Neuroscience Research, 2011, v. 89, n. 2, p. 231, doi. 10.1002/jnr.22537
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- Article
Pathogenic MAPT mutations Q336H and Q336R have isoform-dependent differences in aggregation propensity and microtubule dysfunction.
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- Journal of Neurochemistry, 2021, v. 158, n. 2, p. 455, doi. 10.1111/jnc.15358
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- Article
Pathogenic MAPT mutations Q336H and Q336R have isoform‐dependent differences in aggregation propensity and microtubule dysfunction.
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- Journal of Neurochemistry, 2021, v. 158, n. 1, p. 455, doi. 10.1111/jnc.15358
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- Article
Precision therapeutic targets for COVID-19.
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- Virology Journal, 2021, v. 18, n. 1, p. 1, doi. 10.1186/s12985-021-01526-y
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- Article
Is the Initial Insult in Parkinson's Disease and Dementia with Lewy Bodies a Neuritic Dystrophy?
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- Annals of the New York Academy of Sciences, 2003, v. 991, n. 1, p. 295, doi. 10.1111/j.1749-6632.2003.tb07488.x
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- Article
Prominent amyloid plaque pathology and cerebral amyloid angiopathy in APP V717I (London) carrier – phenotypic variability in autosomal dominant Alzheimer's disease.
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- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-0891-3
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- Article
Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology.
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- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0818-z
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- Publication type:
- Article
Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression.
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- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0787-2
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- Publication type:
- Article
Comparative analyses of the in vivo induction and transmission of α-synuclein pathology in transgenic mice by MSA brain lysate and recombinant α-synuclein fibrils.
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- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0733-3
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- Article
Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau.
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- Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0458-0
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- Article
Neuronal tissue collection from intra-cranial instruments used in deep brain stimulation surgery for Parkinson's disease with implications for study of alpha-synuclein.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-72542-5
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- Publication type:
- Article
Distinct Region-Specific α-Synuclein Oligomers in A53T Transgenic Mice: Implications for Neurodegeneration.
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- Journal of Neuroscience, 2010, v. 30, n. 9, p. 3409, doi. 10.1523/JNEUROSCI.4977-09.2010
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- Publication type:
- Article
Cytosolic Catechols Inhibit α-Synuclein Aggregation and Facilitate the Formation of Intracellular Soluble Oligomeric Intermediates.
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- Journal of Neuroscience, 2006, v. 26, n. 39, p. 10068, doi. 10.1523/JNEUROSCI.0896-06.2006
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- Article
Mutations in LRRK2 as a Cause of Parkinson's Disease.
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- NeuroSignals (Karger AG), 2008, v. 16, n. 1, p. 99, doi. 10.1159/000109764
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- Publication type:
- Article
A multiverse of α-synuclein: investigation of prion strain properties with carboxyl-terminal truncation specific antibodies in animal models.
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- Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01805-z
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- Article
Human tauopathy strains defined by phosphorylation in R1-R2 repeat domains of tau.
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- Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-023-01664-0
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- Publication type:
- Article
Carboxyl truncation of α-synuclein occurs early and is influenced by human APOE genotype in transgenic mouse models of α-synuclein pathogenesis.
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- Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-023-01623-9
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- Publication type:
- Article
Combinatorial model of amyloid β and tau reveals synergy between amyloid deposits and tangle formation.
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- Neuropathology & Applied Neurobiology, 2022, v. 48, n. 2, p. 1, doi. 10.1111/nan.12779
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- Article
Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary.
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- Cancer (0008543X), 2000, v. 88, n. 9, p. 2154, doi. 10.1002/(SICI)1097-0142(20000501)88:9<2154::AID-CNCR23>3.0.CO;2-9
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- Article
Characterization of antibodies that selectively detect α-synuclein in pathological inclusions.
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- Acta Neuropathologica, 2008, v. 116, n. 1, p. 37, doi. 10.1007/s00401-008-0375-1
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- Article
Tau and 14-3-3 in glial cytoplasmic inclusions of multiple system atrophy.
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- Acta Neuropathologica, 2003, v. 106, n. 3, p. 243, doi. 10.1007/s00401-003-0726-x
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- Article
Concurrence of α-synuclein and tau brain pathology in the Contursi kindred.
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- Acta Neuropathologica, 2002, v. 104, n. 1, p. 7, doi. 10.1007/s00401-002-0563-3
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- Publication type:
- Article
Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance.
- Published in:
- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00434-4
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- Publication type:
- Article
Tau mutation S356T in the three repeat isoform leads to microtubule dysfunction and promotes prion-like seeded aggregation.
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- Frontiers in Neuroscience, 2023, p. 1, doi. 10.3389/fnins.2023.1181804
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- Article
Biochemical and pathological characterization of Lrrk2.
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- Annals of Neurology, 2006, v. 59, n. 2, p. 315
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- Publication type:
- Article