We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Ulcerative Keratitis Following Particulate Elemental Gold Deposition.
- Authors
Raj, Akash; Williams, Geraint P.; Hawksworth, Nicholas R.
- Abstract
Purpose: To describe a case of 68-year-old male industrial chemist who received a chemical injury after a gold/amine compound exploded causing bilateral eye injuries. No apparent long-term problems were anticipated. After cataract extraction 40 years later, he developed a localized ulcerative keratitis adjacent to embedded gold in the cornea. Methods: To describe the clinical features, management, and outcomes. Results: Successful treatment with topical hydrocortisone was achieved. Subsequently, 3 further episodes of ulcerative keratitis were treated with topical steroid therapy without need for systemic immunosuppression. A systemic vasculitic/autoimmune screen was normal. Discussion: Ocular chrysiasis is well recognized after systemic gold administration and is normally considered inert, but in this case exogenous gold deposition might have been a contributing factor to very localized and repeated episodes of stromal erosion in this man, many years after the original injury. To the best of our knowledge this is the first such reported case.
- Subjects
CORNEAL ulcer; OCULAR injuries; HEALTH outcome assessment; IMMUNOSUPPRESSION; OCULAR pharmacology; THEORY of knowledge
- Publication
Journal of Ocular Pharmacology & Therapeutics, 2012, Vol 28, Issue 3, p323
- ISSN
1080-7683
- Publication type
Article
- DOI
10.1089/jop.2011.0144