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- Title
Diabetes mellitus prevalence in tuberculosis patients and the background population in Guinea-Bissau: a disease burden study from the capital Bissau.
- Authors
Haraldsdottir, Thorny L.; Rudolf, Frauke; Bjerregaard-Andersen, Morten; Stochholm, Kirstine; Gomes, Victor F.; Beck-Nielsen, Henning; Ostergaard, Lars; Aaby, Peter; Wejse, Christian
- Abstract
Background Data regarding the association between diabetes mellitus (DM) and tuberculosis (TB) in Africa are scare. We did a DM screening survey among TB patients and non-TB controls in Guinea-Bissau. Methods The study was conducted at the Bandim Health Project (BHP) in the capital Bissau. From July 2010 to July 2011, newly diagnosed TB cases were identified through a TB notification system. Concurrently, non-TB controls were selected randomly from the BHP's demographic surveillance database and visited at home. Participants were tested using fasting blood glucose (FBG) measurements. DM was diagnosed as FBG ≥7 mmol/l. Our survey was linked to the patient database at the only existing Diabetes Clinic in Bissau. Results TB patients (n=110) were older than the controls (n=572) (35 vs 31 years; p=0.02), more often male (55% vs 37%; p<0.001) and had a lower body mass index (18.7 vs 24.2 kg/m2; p<0.001). The prevalence of DM was 2.8% (3/107) for TB patients and 2.1% (11/531) for controls (p=0.64). Excluding two controls already receiving anti-diabetic treatment, the prevalence of DM was 2.8% (3/107) vs 1.7% (9/529) (p=0.44). Conclusions The prevalence of DM was low, also among TB patients. No association between DM and TB was found.
- Subjects
BISSAU (Guinea-Bissau); DIABETES; TUBERCULOSIS patients; DISEASE prevalence; BLOOD sugar; HYPOGLYCEMIC agents
- Publication
Transactions of the Royal Society of Tropical Medicine & Hygiene, 2015, Vol 109, Issue 6, p400
- ISSN
0035-9203
- Publication type
Article
- DOI
10.1093/trstmh/trv030