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- Title
New chapter unfolding in the fight against dengue with an unwritten ending.
- Authors
Thiry, Georges; Hombach, Joachim; Constenla, Dagna; Carvalho, Ana; Durbin, Anna
- Abstract
The article discusses the authors' view on the first Phase 3 trial of a vaccine to fight against dengue. Conducted across several Asian countries, the trial evaluated the efficacy and safety of the Sanofi Pasteur tetravalent dengue vaccine candidate from Sanofi-Aventis SA. Results of the Phase 3 trial suggested a limited understanding of dengue immunology and inability to measure protective immune responses.
- Subjects
CLINICAL trials; VIRAL vaccines; VACCINE effectiveness; DENGUE; PREVENTIVE medicine; SANOFI-Aventis SA; MEDICATION safety
- Publication
Transactions of the Royal Society of Tropical Medicine & Hygiene, 2014, Vol 108, Issue 10, p597
- ISSN
0035-9203
- Publication type
Article
- DOI
10.1093/trstmh/tru149