We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Effect of P2 receptor blockade on cutaneous vasodilation during rest and exercise in the heat in young men.
- Authors
Fujii, Naoto; Meade, Robert D.; Louie, Jeffrey C.; Akbari, Pegah; Boulay, Pierre; Sigal, Ronald J.; Kenny, Glen P.
- Abstract
We assessed the role of purinergic P2 receptors in the regulation of cutaneous vasodilation in young adults at rest and during intermittent moderate-intensity exercise in the heat (35 °C). P2 receptor blockade augmented resting cutaneous vasodilation but had no influence during and following exercise. This increase was partly diminished by nitric oxide synthase inhibition. These results suggest a functional role of P2 receptors in the regulation of cutaneous vascular tone during ambient heat exposure at rest.
- Subjects
VASODILATION; CELL receptors; HEAT; MICROCIRCULATION; RELAXATION for health
- Publication
Applied Physiology, Nutrition & Metabolism, 2018, Vol 43, Issue 3, p312
- ISSN
1715-5312
- Publication type
Article
- DOI
10.1139/apnm-2017-0700