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- Title
In response to Joubeh and Singh: Allergic reactions to platelets; to B or not to B?
- Authors
Rossi, Siera; Wendt, Linder; Ballas, Zuhair; Knudson, C. Michael
- Abstract
Five other Type O patients (Table 2 #3-7) were found that had allergic reactions to all B antigen positive units they received but these patients received fewer platelet transfusions, and all had just a single allergic reaction making the possibility that this occurred by chance much higher. While likely under-powered, this does not support the possibility that psoralen treated platelets increase allergic reaction rates as suggested previously.[1] In our data set there were 10 type O patients and 4 type A patients who had allergic reactions to B or AB platelets. We read the recent letter by Joubeh and Singh discussing allergic reactions to psoralen-treated platelets (PI-Platelets) and found their data intriguing.[1] These authors describe two cases of O+ male patients developing allergic reactions after psoralen-treated platelet transfusions, and they wonder whether PI-Platelets may cause allergic transfusion reactions.
- Subjects
ALLERGIES; BLOOD transfusion reaction; BLOOD platelets; ABO blood group system
- Publication
Transfusion, 2022, Vol 62, Issue 12, p2655
- ISSN
0041-1132
- Publication type
Article
- DOI
10.1111/trf.17161