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- Title
It's time to phase out "serologic weak D phenotype" and resolve D types with RHD genotyping including weak D type 4.
- Authors
Flegel, Willy A.; Denomme, Gregory A.; Queenan, John T.; Johnson, Susan T.; Keller, Margaret A.; Westhoff, Connie M.; Katz, Louis M.; Delaney, Meghan; Vassallo, Ralph R.; Simon, Clayton D.; Sandler, S. Gerald
- Abstract
ABBREVIATIONS ACOG American College of Obstetricians and Gynecologists RhIG Rh immune globulin In 2015, the AABB and the College of American Pathologists sponsored an Interorganizational Work Group on I RHD i Genotyping,[1] inviting the American College of Obstetricians and Gynecologists (ACOG), American Red Cross, America's Blood Centers, and Armed Services Blood Program to recommend organizational representatives. As cost-effective and quicker methods for managing serologic weak D phenotypes become available, the focus should turn to developing protocols for managing patients with I RHD i alleles, who do not have a serologic weak D phenotype, but who are at risk for developing anti-D, such as I RHD*DIIIa i and I RHD*DIVa i . Serological weak D phenotypes: a review and guidance for interpreting the RhD blood type using the RHD genotype.
- Subjects
PHENOTYPES; BLOOD transfusion reaction; BLOOD groups; MOLECULAR genetics; RESEARCH; RESEARCH methodology; ALLELES; EVALUATION research; MEDICAL cooperation; COMPARATIVE studies; RH factor; GENOTYPES; RESEARCH funding; RHO(D) immune globulin
- Publication
Transfusion, 2020, Vol 60, Issue 4, p855
- ISSN
0041-1132
- Publication type
journal article
- DOI
10.1111/trf.15741