We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
A survey evaluating surgeons' peri-operative usage of acetyl-salicylic acid (ASA) and their willingness to enroll their patients in a perioperative ASA randomized controlled trial.
- Authors
Hiralal, Rajesh; Guyatt, Gordon; Bhandari, Mohit; Cook, Deborah; Berwanger, Otavio; De Beer, Justin; Cina, Claudio; Buckley, Norm; Villar, Juan Carlos; Montori, Victor; Marcaccio, Michael; Paul, James; Whiteacre, Laura; Devereaux, P J
- Abstract
<bold>Purpose: </bold>Major cardiovascular complications associated with noncardiac surgery represent a substantial population health problem for which there are no established efficacious and safe prophylactic interventions. Acetyl-salicylic acid (ASA) represents a promising intervention. The objective of this study was to determine surgeons' perioperative usage of ASA, and if they would enroll their patients in a perioperative ASA randomized controlled trial (RCT).<bold>Methods: </bold>Cross-sectional survey of all practicing Canadian general, orthopedic, and vascular surgeons. Our mailed, self-administered survey asked surgeons to consider only their patients who were at risk of a major perioperative cardiovascular complication.<bold>Results: </bold>The response rate was 906/1854 (49%). For patients taking ASA chronically, there was marked variability regarding ASA continuation prior to surgery amongst the general and orthopedic surgeons, whereas 76% of vascular surgeons continued ASA in 81-100% of their patients. For patients not taking ASA chronically, approaches to starting ASA prior to surgery were variable amongst the vascular surgeons, whereas 70% of general and 82% of orthopaedic surgeons did not start ASA. For patients taking ASA chronically, 73% of general surgeons, 70% of orthopaedic surgeons, and 36% of vascular surgeons would allow at least 40% of their patients to participate in a perioperative RCT comparing stopping versus continuing ASA. For patients not taking ASA chronically, most general (76%), orthopaedic (67%), and vascular (51%) surgeons would allow at least 40% of their patients to participate in a perioperative RCT comparing starting ASA versus placebo.<bold>Conclusion: </bold>This national survey demonstrates that perioperative ASA usage as reported by surgeons is variable, identifying the need for, and community interest in, a large perioperative ASA trial.
- Publication
Clinical & Investigative Medicine, 2010, Vol 33, Issue 6, pE375
- ISSN
0147-958X
- Publication type
journal article
- DOI
10.25011/cim.v33i6.14588