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Leveraging crowdsourcing to accelerate global health solutions.
Published in:
2019
By:
- Davis, Sage;
- Button-Simons, Katrina;
- Bensellak, Taoufik;
- Ahsen, Eren Mehmet;
- Checkley, Lisa;
- Foster, Gabriel J.;
- Su, Xinzhuan;
- Moussa, Ahmed;
- Mapiye, Darlington;
- Khoo, Sok Kean;
- Nosten, Francois;
- Anderson, Timothy J. C.;
- Vendrely, Katelyn;
- Bletz, Julie;
- Yu, Thomas;
- Panji, Sumir;
- Ghouila, Amel;
- Mulder, Nicola;
- Norman, Thea;
- Kern, Steven
Publication type:
Letter
Erratum: Prediction of human population responses to toxic compounds by a collaborative competition.
Published in:
Nature Biotechnology, 2015, v. 33, n. 10, p. 1109, doi. 10.1038/nbt1015-1109a
By:
- Eduati, Federica;
- Mangravite, Lara M;
- Wang, Tao;
- Tang, Hao;
- Bare, J Christopher;
- Huang, Ruili;
- Norman, Thea;
- Kellen, Mike;
- Menden, Michael P;
- Yang, Jichen;
- Zhan, Xiaowei;
- Zhong, Rui;
- Xiao, Guanghua;
- Xia, Menghang;
- Abdo, Nour;
- Kosyk, Oksana;
- Friend, Stephen;
- Dearry, Allen;
- Simeonov, Anton;
- Tice, Raymond R
Publication type:
Article
Prediction of human population responses to toxic compounds by a collaborative competition.
Published in:
Nature Biotechnology, 2015, v. 33, n. 9, p. 933, doi. 10.1038/nbt.3299
By:
- Eduati, Federica;
- Mangravite, Lara M;
- Wang, Tao;
- Tang, Hao;
- Bare, J Christopher;
- Huang, Ruili;
- Norman, Thea;
- Kellen, Mike;
- Menden, Michael P;
- Yang, Jichen;
- Zhan, Xiaowei;
- Zhong, Rui;
- Xiao, Guanghua;
- Xia, Menghang;
- Abdo, Nour;
- Kosyk, Oksana
Publication type:
Article
Metcalfe's law and the biology information commons.
Published in:
Nature Biotechnology, 2013, v. 31, n. 4, p. 297, doi. 10.1038/nbt.2555
By:
- Friend, Stephen H;
- Norman, Thea C
Publication type:
Article
Integrating transcriptional and metabolite profiles to direct the engineering of lovastatin-producing fungal strains.
Published in:
Nature Biotechnology, 2003, v. 21, n. 2, p. 150, doi. 10.1038/nbt781
By:
- Askenazi, Manor;
- Driggers, Edward M.;
- Holtzman, Douglas A.;
- Norman, Thea C.;
- Iverson, Sara;
- Zimmer, Daniel P.;
- Boers, Mary-Ellen;
- Blomquist, Paul R.;
- Martinez, Eduardo J.;
- Monreal, Alex W.;
- Feibelman, Toby P.;
- Mayorga, Maria E.;
- Maxon, Mary E.;
- Sykes, Kristie;
- Tobin, Jenny Vittum;
- Cordero, Etchell;
- Salama, Sofie R.;
- Trueheart, Joshua;
- Royer, John C.
Publication type:
Article
Global optimization of somatic variant identification in cancer genomes with a global community challenge.
Published in:
Nature Genetics, 2014, v. 46, n. 4, p. 318, doi. 10.1038/ng.2932
By:
- Boutros, Paul C;
- Ewing, Adam D;
- Ellrott, Kyle;
- Norman, Thea C;
- Dang, Kristen K;
- Hu, Yin;
- Kellen, Michael R;
- Suver, Christine;
- Bare, J Christopher;
- Stein, Lincoln D;
- Spellman, Paul T;
- Stolovitzky, Gustavo;
- Friend, Stephen H;
- Margolin, Adam A;
- Stuart, Joshua M
Publication type:
Article
Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection.
Published in:
Nature Methods, 2015, v. 12, n. 7, p. 623, doi. 10.1038/nmeth.3407
By:
- Ewing, Adam D;
- Houlahan, Kathleen E;
- Hu, Yin;
- Ellrott, Kyle;
- Caloian, Cristian;
- Yamaguchi, Takafumi N;
- Bare, J Christopher;
- P'ng, Christine;
- Waggott, Daryl;
- Sabelnykova, Veronica Y;
- Kellen, Michael R;
- Norman, Thea C;
- Haussler, David;
- Friend, Stephen H;
- Stolovitzky, Gustavo;
- Margolin, Adam A;
- Stuart, Joshua M;
- Boutros, Paul C
Publication type:
Article
Participatory development of a target policy profile to support soil-transmitted helminth elimination.
Published in:
Frontiers in Health Services, 2024, p. 1, doi. 10.3389/frhs.2023.1310694
By:
- Means, Arianna Rubin;
- List, Kellie;
- Roll, Amy;
- Gwayi-Chore, Marie-Claire;
- Dolley, Shawn;
- Schünemann, Holger J.;
- Norman, Thea C.;
- Walson, Judd L.
Publication type:
Article
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-09799-2
By:
- Menden, Michael P.;
- Wang, Dennis;
- Mason, Mike J.;
- Szalai, Bence;
- Bulusu, Krishna C.;
- Yuanfang Guan;
- Yu, Thomas;
- Jaewoo Kang;
- Minji Jeon;
- Wolfinger, Russ;
- Tin Nguyen;
- Zaslavskiy, Mikhail;
- Ghazoui, Zara;
- Ahsen, Mehmet Eren;
- Vogel, Robert;
- Neto, Elias Chaibub;
- Norman, Thea;
- Tang, Eric K. Y.;
- Garnett, Mathew J.;
- Di Veroli, Giovanni Y.
Publication type:
Article
Systematic Analysis of Challenge-Driven Improvements in Molecular Prognostic Models for Breast Cancer.
Published in:
Science Translational Medicine, 2013, v. 5, n. 181, p. 1, doi. 10.1126/scitranslmed.3006112
By:
- Margolin, Adam A.;
- Bilal, Erhan;
- Erich Huang;
- Norman, Thea C.;
- Ottestad, Lars;
- Mecham, Brigham H.;
- Sauerwine, Ben;
- Kellen, Michael R.;
- Mangravite, Lara M.;
- Furia, Matthew D.;
- Vollan, Hans Kristian Moen;
- Rueda, Oscar M.;
- Guinney, Justin;
- Deflaux, Nicole A.;
- Hoff, Bruce;
- Schildwachter, Xavier;
- Russnes, Hege G.;
- Park, Daehoon;
- Vang, Veronica O.;
- Pirtle, Tyler
Publication type:
Article
Leveraging Crowdsourcing to Facilitate the Discovery of New Medicines.
Published in:
Science Translational Medicine, 2011, v. 3, n. 88, p. 1, doi. 10.1126/scitranslmed.3002678
By:
- Norman, Thea C.;
- Bountra, Chas;
- Edwards, Aled M.;
- Yamamoto, Keith R.;
- Friend, Stephen H.
Publication type:
Article
The Precompetitive Space: Time to Move the Yardsticks.
Published in:
Science Translational Medicine, 2011, v. 3, n. 76, p. 1, doi. 10.1126/scitranslmed.3002399
By:
- Norman, Thea;
- Edwards, Aled;
- Bountra, Chas;
- Friend, Stephen
Publication type:
Article
A Crowdsourcing Approach to Developing and Assessing Prediction Algorithms for AML Prognosis.
Published in:
PLoS Computational Biology, 2016, v. 12, n. 6, p. 1, doi. 10.1371/journal.pcbi.1004890
By:
- Noren, David P.;
- Long, Byron L.;
- Norel, Raquel;
- Rrhissorrakrai, Kahn;
- Hess, Kenneth;
- Hu, Chenyue Wendy;
- Bisberg, Alex J.;
- Schultz, Andre;
- Engquist, Erik;
- Liu, Li;
- Lin, Xihui;
- Chen, Gregory M.;
- Xie, Honglei;
- Hunter, Geoffrey A. M.;
- Boutros, Paul C.;
- Stepanov, Oleg;
- null, null;
- Norman, Thea;
- Friend, Stephen H.;
- Stolovitzky, Gustavo
Publication type:
Article
Germline contamination and leakage in whole genome somatic single nucleotide variant detection.
Published in:
BMC Bioinformatics, 2018, v. 19, p. 1, doi. 10.1186/s12859-018-2046-0
By:
- Sendorek, Dorota H.;
- Caloian, Cristian;
- Ellrott, Kyle;
- Bare, J. Christopher;
- Yamaguchi, Takafumi N.;
- Ewing, Adam D.;
- Houlahan, Kathleen E.;
- Norman, Thea C.;
- Margolin, Adam A.;
- Stuart, Joshua M.;
- Boutros, Paul C.
Publication type:
Article
The Prostate Cancer DREAM Challenge: A Community-Wide Effort to Use Open Clinical Trial Data for the Quantitative Prediction of Outcomes in Metastatic Prostate Cancer.
Published in:
2015
By:
- Abdallah, Kald;
- Hugh‐Jones, Charles;
- Norman, Thea;
- Friend, Stephen;
- Stolovitzky, Gustavo
Publication type:
Editorial
Stratification of amyotrophic lateral sclerosis patients: a crowdsourcing approach.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-36873-4
By:
- Kueffner, Robert;
- Zach, Neta;
- Bronfeld, Maya;
- Norel, Raquel;
- Atassi, Nazem;
- Balagurusamy, Venkat;
- Di Camillo, Barbara;
- Chio, Adriano;
- Cudkowicz, Merit;
- Dillenberger, Donna;
- Garcia-Garcia, Javier;
- Hardiman, Orla;
- Hoff, Bruce;
- Knight, Joshua;
- Leitner, Melanie L.;
- Li, Guang;
- Mangravite, Lara;
- Norman, Thea;
- Wang, Liuxia;
- The ALS Stratification Consortium
Publication type:
Article
Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection.
Published in:
Genome Biology, 2018, v. 19, n. 1, p. N.PAG, doi. 10.1186/s13059-018-1539-5
By:
- Lee, Anna Y.;
- Ewing, Adam D.;
- Ellrott, Kyle;
- Hu, Yin;
- Houlahan, Kathleen E.;
- Bare, J. Christopher;
- Espiritu, Shadrielle Melijah G.;
- Huang, Vincent;
- Dang, Kristen;
- Chong, Zechen;
- Caloian, Cristian;
- Yamaguchi, Takafumi N.;
- Kellen, Michael R.;
- Chen, Ken;
- Norman, Thea C.;
- Friend, Stephen H.;
- Guinney, Justin;
- Stolovitzky, Gustavo;
- Haussler, David;
- Margolin, Adam A.
Publication type:
Article
FGF21 Analogs of Sustained Action Enabled by Orthogonal Biosynthesis Demonstrate Enhanced Antidiabetic Pharmacology in Rodents.
Published in:
Diabetes, 2012, v. 61, n. 2, p. 505, doi. 10.2337/db11-0838
By:
- Mu, James;
- Pinkstaff, Jason;
- Zhihua Li;
- Skidmore, Lillian;
- Nina Li;
- Myler, Heather;
- Dallas-Yang, Qing;
- Putnam, Anna-Maria;
- Jun Yao;
- Bussell, Stuart;
- Wu, Margaret;
- Norman, Thea C.;
- Rodriguez, Carlos G.;
- Kimmel, Bruce;
- Metzger, Joseph M.;
- Manibusan, Anthony;
- Lee, Darin;
- Zaller, Dennis M.;
- Zhang, Bei B.;
- DiMarchi, Richard D.
Publication type:
Article

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