We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Atypical cartilaginous tumor/chondrosarcoma, grade 1, of the mastoid in three family members: A new entity.
- Authors
Frisch, Christopher D.; Inwards, Carrie Y.; Lalich, Ian J.; Carter, Jodi M.; Neff, Brian A
- Abstract
We present a case series of a family with three members having cartilaginous tumors of the mastoid. All patients presented between the ages of 9 to 12 years with acute onset facial nerve paralysis. Histologic analysis of all tumors showed similar features, consistent with atypical cartilaginous tumors/chondrosarcoma, low-grade. Conventional cytogenetic analysis performed on one of the sons' tumor showed no evidence of chromosomal abnormality. High-resolution array comparative genomic hybridization performed on the same patient's blood also showed no unbalanced chromosomal abnormality. This is the first report of family members with this unusual combination of clinical, radiologic, and histologic finding. Laryngoscope, 126:E310-E313, 2016.
- Subjects
MASTOID process diseases; TUMORS; FACIAL paralysis; CHONDROSARCOMA; CYTOGENETICS
- Publication
Laryngoscope, 2016, Vol 126, Issue 9, pE310
- ISSN
0023-852X
- Publication type
journal article
- DOI
10.1002/lary.25802