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- Title
The residual effect of coronovirus disease 2019 on olfactory acuity and mucociliary clearance time: a cross-sectional, controlled study.
- Authors
Kandemir, S; Pamuk, A E
- Abstract
Objective: This study evaluated the olfactory, sinonasal and mucociliary functions of patients with post-coronavirus disease 2019 long-term persistent olfactory dysfunction. Method: Three groups of 30 patients each were formed: patients with a history of coronavirus disease 2019 infection with self-reported, persistent, sudden-onset olfactory dysfunction (group 1), patients with a history of coronavirus disease 2019 infection without any self-reported olfactory dysfunction (group 2) and healthy controls with no history of coronavirus disease 2019 infection (group 3). Saccharin time, Sniffin' Sticks, Turkish Nasal Obstruction Symptom Evaluation and Sino-Nasal Outcome Test 22 scores were compared. Results: Turkish Nasal Obstruction Symptom Evaluation scores were similar between groups (p = 0.252). Sino-Nasal Outcome Test-22 scores were higher in group 1 than groups 2 and 3 (p < 0.01 and p < 0.001, respectively). Saccharin time was significantly longer in group 1 than groups 2 and 3 (p < 0.05 and p < 0.01, respectively). Group 1 had lower olfactory scores than groups 2 and 3 (p < 0.001 and p < 0.001, respectively). Conclusion: Mucociliary clearance time was significantly prolonged in patients with post-coronavirus disease 2019 persistent olfactory dysfunction. Coronavirus disease 2019 infection was likely to cause asymptomatic olfactory dysfunction.
- Subjects
CROSS-sectional method; SELF-evaluation; SACCHARIN; NOSE; RESPIRATORY obstructions; SMELL disorders; MUCOCILIARY system; DESCRIPTIVE statistics; COMPUTED tomography; POLYMERASE chain reaction; DATA analysis software; COVID-19 pandemic
- Publication
Journal of Laryngology & Otology, 2022, Vol 136, Issue 8, p742
- ISSN
0022-2151
- Publication type
Article
- DOI
10.1017/S0022215122000925