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- Title
Immune Deviation and Alleviation of Allergic Reactions in Mice Subjected to Dietary Restriction.
- Authors
Yamazaki, Ken-ichi; Nako-Nagaoka, Noriko; Suzuki, Tomomi; Shida, Kan; Nanno, Masanobu
- Abstract
The article presents a study which examines the effect of dietary restriction (DR) on immune functions in mice. It reveals that DR has the ability to suppress the allergic reaction caused by intranasal challenge with ovalbumin (OVA). It also was found that it retarded the increase in body weight and can reduce the cytolytic activity on killer cells in the spleen. It suggests that DR can prevent the expansion of OVA-specific IL-4 producing T cells due to the suppression of the allergic reaction.
- Subjects
ALLERGIES; BODY weight; KILLER cells; T cells; LABORATORY mice
- Publication
Bioscience, Biotechnology & Biochemistry, 2009, Vol 73, Issue 12, p2705
- ISSN
0916-8451
- Publication type
Article
- DOI
10.1271/bbb.90561