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PGC-1α and MEF2 Regulate the Transcription of the Carnitine Transporter OCTN2 Gene in C2C12 Cells and in Mouse Skeletal Muscle.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 20, p. 12304, doi. 10.3390/ijms232012304
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- Article
Mitochondrial Toxicity Associated with Imatinib and Sorafenib in Isolated Rat Heart Fibers and the Cardiomyoblast H9c2 Cell Line.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 4, p. 2282, doi. 10.3390/ijms23042282
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- Article
Effects of Simvastatin on Lipid Metabolism in Wild-Type Mice and Mice with Muscle PGC-1α Overexpression.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4950, doi. 10.3390/ijms22094950
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- Article
Para-Halogenation of Amphetamine and Methcathinone Increases the Mitochondrial Toxicity in Undifferentiated and Differentiated SH-SY5Y Cells.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 8, p. 2841, doi. 10.3390/ijms21082841
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- Article
Exogenous Iron Increases Fasciocidal Activity and Hepatocellular Toxicity of the Synthetic Endoperoxides OZ78 and MT04.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 19, p. 4880, doi. 10.3390/ijms20194880
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- Article
Molecular Toxicological Mechanisms of Synthetic Cathinones on C2C12 Myoblasts.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 7, p. 1561, doi. 10.3390/ijms20071561
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- Publication type:
- Article
Development and Validation of a Highly Sensitive LC-MS/MS Method for the Analysis of Bile Acids in Serum, Plasma, and Liver Tissue Samples.
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- Metabolites (2218-1989), 2020, v. 10, n. 7, p. 282, doi. 10.3390/metabo10070282
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- Article
Pressure overload-induced mild cardiac hypertrophy reduces left ventricular transmural differences in mitochondrial respiratory chain activity and increases oxidative stress.
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- Frontiers in Physiology, 2012, v. 3, p. 1, doi. 10.3389/fphys.2012.00332
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- Publication type:
- Article
Pressure overload-induced mild cardiac hypertrophy reduces left ventricular transmural differences in mitochondrial respiratory chain activity and increases oxidative stress.
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- Frontiers in Physiology, 2012, v. 3, p. 1, doi. 10.3389/fphys.2012.00332
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- Publication type:
- Article
Comparative Effects of Metamizole (Dipyrone) and Naproxen on Renal Function and Prostacyclin Synthesis in Salt-Depleted Healthy Subjects - A Randomized Controlled Parallel Group Study.
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- Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.620635
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- Article
Effect of eccentric versus concentric exercise training on mitochondrial function.
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- Muscle & Nerve, 2014, v. 50, n. 5, p. 803, doi. 10.1002/mus.24215
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- Article
Mitochondria of trained skeletal muscle are protected from deleterious effects of statins.
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- Muscle & Nerve, 2012, v. 46, n. 3, p. 367, doi. 10.1002/mus.23309
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- Article
Implication of Lipids in Calcified Aortic Valve Pathogenesis: Why Did Statins Fail?
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- Journal of Clinical Medicine, 2022, v. 11, n. 12, p. 3331, doi. 10.3390/jcm11123331
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- Article
Imatinib and Dasatinib Provoke Mitochondrial Dysfunction Leading to Oxidative Stress in C2C12 Myotubes and Human RD Cells.
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- Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.01106
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- Publication type:
- Article
Lapatinib Activates the Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 Pathway in HepG2 Cells.
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- Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00944
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- Article
Insulin prevents and reverts simvastatin-induced toxicity in C2C12 skeletal muscle cells.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-43938-5
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- Article
Muscles Susceptibility to Ischemia-Reperfusion Injuries Depends on Fiber Type Specific Antioxidant Level.
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- Frontiers in Physiology, 2017, v. 8, p. 1, doi. 10.3389/fphys.2017.00052
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- Article
Impaired Exercise Performance and Skeletal Muscle Mitochondrial Function in Rats with Secondary Carnitine Deficiency.
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- Frontiers in Physiology, 2016, p. 1, doi. 10.3389/fphys.2016.00345
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- Publication type:
- Article
Left Ventricular Transmural Gradient in Mitochondrial Respiration Is Associated with Increased Sub-Endocardium Nitric Oxide and Reactive Oxygen Species Productions.
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- Frontiers in Physiology, 2016, p. 1, doi. 10.3389/fphys.2016.00331
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- Article
Skeletal muscle mitochondrial dysfunction precedes right ventricular impairment in experimental pulmonary hypertension.
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- Molecular & Cellular Biochemistry, 2013, v. 373, n. 1/2, p. 161, doi. 10.1007/s11010-012-1485-6
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- Article
Mechanisms of toxicity associated with six tyrosine kinase inhibitors in human hepatocyte cell lines.
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- Journal of Applied Toxicology, 2018, v. 38, n. 3, p. 418, doi. 10.1002/jat.3551
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- Article
Hepatotoxicity Due to Azole Antimycotic Agents in a HLA B*35:02-Positive Patient.
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- Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00645
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- Article
Effect of l-carnitine supplementation on the body carnitine pool, skeletal muscle energy metabolism and physical performance in male vegetarians.
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- European Journal of Nutrition, 2016, v. 55, n. 1, p. 207, doi. 10.1007/s00394-015-0838-9
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- Article
Effect of carnitine, acetyl-, and propionylcarnitine supplementation on the body carnitine pool, skeletal muscle composition, and physical performance in mice.
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- European Journal of Nutrition, 2014, v. 53, n. 6, p. 1313, doi. 10.1007/s00394-013-0631-6
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- Article
Apparent Km of mitochondria for oxygen computed from Vmax measured in permeabilized muscle fibers is lower in water enriched in oxygen by electrolysis than injection.
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- Drug Design, Development & Therapy, 2015, v. 9, p. 3589, doi. 10.2147/DDDT.S81891
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- Publication type:
- Article
Hepatic Effects of Pharmacological Doses of Hydroxy-Cobalamin[c-lactam] in Mice.
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- PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0171026
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- Article
PGC‐1α plays a pivotal role in simvastatin‐induced exercise impairment in mice.
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- Acta Physiologica, 2020, v. 228, n. 4, p. 1, doi. 10.1111/apha.13402
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- Article
PGC-1β modulates statin-associated myotoxicity in mice.
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- Archives of Toxicology, 2019, v. 93, n. 2, p. 487, doi. 10.1007/s00204-018-2369-7
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- Article
IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes.
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- Archives of Toxicology, 2017, v. 91, n. 5, p. 2223, doi. 10.1007/s00204-016-1871-z
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- Publication type:
- Article
Simvastatin induces mitochondrial dysfunction and increased atrogin-1 expression in H9c2 cardiomyocytes and mice in vivo.
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- Archives of Toxicology, 2016, v. 90, n. 1, p. 203, doi. 10.1007/s00204-014-1378-4
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- Publication type:
- Article
Simvastatin Impairs Glucose Homeostasis in Mice Depending on PGC-1α Skeletal Muscle Expression.
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- Biomedicines, 2020, v. 8, n. 9, p. 351, doi. 10.3390/biomedicines8090351
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- Article
Reactive Metamizole Metabolites Enhance the Toxicity of Hemin on the ATP Pool in HL60 Cells by Inhibition of Glycolysis.
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- Biomedicines, 2020, v. 8, n. 7, p. 212, doi. 10.3390/biomedicines8070212
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- Article
Hyperthermia Increases Neurotoxicity Associated with Novel Methcathinones.
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- Cells (2073-4409), 2020, v. 9, n. 4, p. 965, doi. 10.3390/cells9040965
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- Article
Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis.
- Published in:
- Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00367
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- Article
Liver Cirrhosis Affects the Pharmacokinetics of the Six Substrates of the Basel PhenotypingCocktail Differently.
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- Clinical Pharmacokinetics, 2022, v. 61, n. 7, p. 1039, doi. 10.1007/s40262-022-01119-0
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- Article
Effect of chronic pre-treatment with angiotensin converting enzyme inhibition on skeletal muscle mitochondrial recovery after ischemia/reperfusion.
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- Fundamental & Clinical Pharmacology, 2010, v. 24, n. 3, p. 333, doi. 10.1111/j.1472-8206.2009.00763.x
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- Article
Opposite effects of statins on mitochondria of cardiac and skeletal muscles: a ‘mitohormesis’ mechanism involving reactive oxygen species and PGC-1.
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- European Heart Journal, 2012, v. 33, n. 11, p. 1397, doi. 10.1093/eurheartj/ehr224
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- Article
Effect of the Catechol-O-Methyltransferase Inhibitors Tolcapone and Entacapone on Fatty Acid Metabolism in HepaRG Cells.
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- Toxicological Sciences, 2018, v. 164, n. 2, p. 477, doi. 10.1093/toxsci/kfy101
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- Article
Hepatocellular Toxicity of Imidazole and Triazole Antimycotic Agents.
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- Toxicological Sciences, 2017, v. 157, n. 1, p. 183, doi. 10.1093/toxsci/kfx029
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- Publication type:
- Article
Mechanisms of Hepatocellular Toxicity Associated with Dronedarone—A Comparison to Amiodarone.
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- Toxicological Sciences, 2013, v. 131, n. 2, p. 480, doi. 10.1093/toxsci/kfs298
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- Article
Age Modulates Fe3O4 Nanoparticles Liver Toxicity: Dose-Dependent Decrease in Mitochondrial Respiratory Chain Complexes Activities and Coupling in Middle-Aged as Compared to Young Rats.
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- 2014
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- Publication type:
- Journal Article
Diabetes Worsens Skeletal Muscle Mitochondrial Function, Oxidative Stress, and Apoptosis After Lower-Limb Ischemia-Reperfusion: Implication of the RISK and SAFE Pathways?
- Published in:
- Frontiers in Physiology, 2018, p. 1, doi. 10.3389/fphys.2018.00579
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- Article