OpenURL Connection Search

Select item for more details and to access through your institution.

Ex vivo blockade of PI3K gamma or delta signaling enhances the antitumor potency of adoptively transferred CD8+ T cells.
Published in:
European Journal of Immunology, 2020, v. 50, n. 9, p. 1386, doi. 10.1002/eji.201948455
By:
- Dwyer, Connor J.;
- Arhontoulis, Dimitrios C.;
- Rangel Rivera, Guillermo O;
- Knochelmann, Hannah M.;
- Smith, Aubrey S.;
- Wyatt, Megan M.;
- Rubinstein, Mark P.;
- Atkinson, Carl;
- Thaxton, Jessica E.;
- Neskey, David M.;
- Paulos, Chrystal M.
Publication type:
Article
Putting the brakes on BTLA in T cell-mediated cancer immunotherapy.
Published in:
2010
By:
- Paulos, Chrystal M.;
- June, Carl H.
Publication type:
journal article
Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling.
Published in:
2007
By:
- Paulos, Chrystal M.;
- Wrzesinski, Claudia;
- Kaiser, Andrew;
- Hinrichs, Christian S.;
- Chieppa, Marcello;
- Cassard, Lydie;
- Palmer, Douglas C.;
- Boni, Andrea;
- Muranski, Pawel;
- Zhiya Yu;
- Gattinoni, Luca;
- Antony, Paul A.;
- Rosenberg, Steven A.;
- Restifo, Nicholas P.;
- Yu, Zhiya
Publication type:
journal article
Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8 T cells.
Published in:
2007
By:
- Wrzesinski, Claudia;
- Paulos, Chrystal M.;
- Gattinoni, Luca;
- Palmer, Douglas C.;
- Kaiser, Andrew;
- Zhiya Yu;
- Rosenberg, Steven A.;
- Restifo, Nicholas P.;
- Yu, Zhiya
Publication type:
journal article
Harnessing the Microbiome to Enhance Cancer Immunotherapy.
Published in:
Journal of Immunology Research, 2015, v. 2015, p. 1, doi. 10.1155/2015/368736
By:
- Nelson, Michelle H.;
- Diven, Marshall A.;
- Huff, Logan W.;
- Paulos, Chrystal M.
Publication type:
Article
Harnessing the Microbiome to Enhance Cancer Immunotherapy.
Published in:
2015
By:
- Nelson, Michelle H;
- Diven, Marshall A;
- Huff, Logan W;
- Paulos, Chrystal M
Publication type:
journal article
Genomics meets immunity in pancreatic cancer: Current research and future directions for pancreatic adenocarcinoma immunotherapy.
Published in:
Oncology Reviews, 2019, v. 13, n. 2, p. 102, doi. 10.4081/oncol.2019.430
By:
- Bowers, Jacob S.;
- Bailey, Stefanie R.;
- Rubinstein, Mark P.;
- Paulos, Chrystal M.;
- Camp, E. Ramsay
Publication type:
Article
A human memory T cell subset with stem cell-like properties.
Published in:
Nature Medicine, 2011, v. 17, n. 10, p. 1290, doi. 10.1038/nm.2446
By:
- Gattinoni, Luca;
- Lugli, Enrico;
- Ji, Yun;
- Pos, Zoltan;
- Paulos, Chrystal M;
- Quigley, Máire F;
- Almeida, Jorge R;
- Gostick, Emma;
- Yu, Zhiya;
- Carpenito, Carmine;
- Wang, Ena;
- Douek, Daniel C;
- Price, David A;
- June, Carl H;
- Marincola, Francesco M;
- Roederer, Mario;
- Restifo, Nicholas P
Publication type:
Article
Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells.
Published in:
Nature Medicine, 2009, v. 15, n. 7, p. 808, doi. 10.1038/nm.1982
By:
- Gattinoni, Luca;
- Xiao-Song Zhong;
- Palmer, Douglas C.;
- Yun Ji;
- Hinrichs, Christian S.;
- Zhiya Yu;
- Wrzesinski, Claudia;
- Boni1, Andrea;
- Cassard, Lydie;
- Garvin, Lindsay M.;
- Paulos, Chrystal M.;
- Muranski, Pawel;
- Restifo, Nicholas P.
Publication type:
Article
Potential clinical implications of CD4+CD26high T cells for nivolumab treated melanoma patients.
Published in:
Journal of Translational Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12967-023-04184-6
By:
- Galati, Domenico;
- Zanotta, Serena;
- Capone, Mariaelena;
- Madonna, Gabriele;
- Mallardo, Domenico;
- Romanelli, Marilena;
- Simeone, Ester;
- Festino, Lucia;
- Sparano, Francesca;
- Azzaro, Rosa;
- De Filippi, Rosaria;
- Pinto, Antonio;
- Paulos, Chrystal M.;
- Ascierto, Paolo A.
Publication type:
Article
Perspectives in Immunotherapy: meeting report from the Immunotherapy Bridge, December 1st–2nd, 2021.
Published in:
Journal of Translational Medicine, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12967-022-03471-y
By:
- Ascierto, Paolo A.;
- Avallone, Antonio;
- Bhardwaj, Nina;
- Bifulco, Carlo;
- Bracarda, Sergio;
- Brody, Joshua D.;
- Buonaguro, Luigi;
- Demaria, Sandra;
- Emens, Leisha A.;
- Ferris, Robert L.;
- Galon, Jérôme;
- Khleif, Samir N.;
- Klebanoff, Christopher A.;
- Laskowski, Tamara;
- Melero, Ignacio;
- Paulos, Chrystal M.;
- Pignata, Sandro;
- Ruella, Marco;
- Svane, Inge Marie;
- Taube, Janis M.
Publication type:
Article
Perspectives in Immunotherapy: meeting report from the Immunotherapy Bridge, December 1st-2nd, 2021.
Published in:
2022
By:
- Ascierto, Paolo A.;
- Avallone, Antonio;
- Bhardwaj, Nina;
- Bifulco, Carlo;
- Bracarda, Sergio;
- Brody, Joshua D.;
- Buonaguro, Luigi;
- Demaria, Sandra;
- Emens, Leisha A.;
- Ferris, Robert L.;
- Galon, Jérôme;
- Khleif, Samir N.;
- Klebanoff, Christopher A.;
- Laskowski, Tamara;
- Melero, Ignacio;
- Paulos, Chrystal M.;
- Pignata, Sandro;
- Ruella, Marco;
- Svane, Inge Marie;
- Taube, Janis M.
Publication type:
journal article
Immunological effects of nivolumab immunotherapy in patients with oral cavity squamous cell carcinoma.
Published in:
2020
By:
- Xiong, Ying;
- Neskey, David M;
- Horton, Joshua D;
- Paulos, Chrystal M;
- Knochelmann, Hannah M;
- Armeson, Kent E;
- Young, M Rita I
Publication type:
journal article
Fueling Cancer Immunotherapy With Common Gamma Chain Cytokines.
Published in:
Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00263
By:
- Dwyer, Connor J.;
- Knochelmann, Hannah M.;
- Smith, Aubrey S.;
- Wyatt, Megan M.;
- Rangel Rivera, Guillermo O.;
- Arhontoulis, Dimitrios C.;
- Bartee, Eric;
- Li, Zihai;
- Rubinstein, Mark P.;
- Paulos, Chrystal M.
Publication type:
Article
<italic>N-</italic>acetyl cysteine protects anti-melanoma cytotoxic T cells from exhaustion induced by rapid expansion via the downmodulation of Foxo1 in an Akt-dependent manner.
Published in:
Cancer Immunology, Immunotherapy, 2018, v. 67, n. 4, p. 691, doi. 10.1007/s00262-018-2120-5
By:
- Scheffel, Matthew J.;
- Scurti, Gina;
- Wyatt, Megan M.;
- Garrett-Mayer, Elizabeth;
- Paulos, Chrystal M.;
- Nishimura, Michael I.;
- Voelkel-Johnson, Christina
Publication type:
Article
Strategies for Improving CAR T Cell Persistence in Solid Tumors.
Published in:
Cancers, 2024, v. 16, n. 16, p. 2858, doi. 10.3390/cancers16162858
By:
- Wittling, Megen C.;
- Cole, Anna C.;
- Brammer, Brianna;
- Diatikar, Kailey G.;
- Schmitt, Nicole C.;
- Paulos, Chrystal M.
Publication type:
Article
Novel immunotherapies for hematologic malignancies.
Published in:
Immunological Reviews, 2015, v. 263, n. 1, p. 90, doi. 10.1111/imr.12245
By:
- Nelson, Michelle H.;
- Paulos, Chrystal M.
Publication type:
Article
Preinvasive Colorectal Lesions of African Americans Display an Immunosuppressive Signature Compared to Caucasian Americans.
Published in:
Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2021.659036
By:
- Wallace, Kristin;
- Nahhas, Georges J.;
- Bookhout, Christine;
- Lewin, David N.;
- Paulos, Chrystal M.;
- Nikolaishvili-Feinberg, Nana;
- Cohen, Stephanie M.;
- Guglietta, Silvia;
- Bakhtiari, Ali;
- Camp, E. Ramsay;
- Hill, Elizabeth G.;
- Baron, John A.;
- Wu, Jennifer D.;
- Alekseyenko, Alexander V.
Publication type:
Article
The magic of small-molecule drugs during ex vivo expansion in adoptive cell therapy.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1154566
By:
- Hanwen Zhang;
- Tenzin Passang;
- Ravindranathan, Sruthi;
- Bommireddy, Ramireddy;
- Jajja, Mohammad Raheel;
- Lily Yang;
- Selvaraj, Periasamy;
- Paulos, Chrystal M.;
- Waller, Edmund K.
Publication type:
Article
Perspectives in Immunotherapy: meeting report from Immunotherapy Bridge (Naples, November 30th–December 1st, 2022).
Published in:
Journal of Translational Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12967-023-04117-3
By:
- Ascierto, Paolo A.;
- Avallone, Antonio;
- Bifulco, Carlo;
- Bracarda, Sergio;
- Brody, Joshua D.;
- Emens, Leisha A.;
- Ferris, Robert L.;
- Formenti, Silvia C.;
- Hamid, Omid;
- Johnson, Douglas B.;
- Kirchhoff, Tomas;
- Klebanoff, Christopher A.;
- Lesinski, Gregory B.;
- Monette, Anne;
- Neyns, Bart;
- Odunsi, Kunle;
- Paulos, Chrystal M.;
- Powell Jr., Daniel J.;
- Rezvani, Katayoun;
- Segal, Brahm H.
Publication type:
Article
Platelets subvert T cell immunity against cancer via GARP-TGFβ axis.
Published in:
Science Immunology, 2017, v. 2, n. 11, p. 1, doi. 10.1126/sciimmunol.aai7911
By:
- Rachidi, Saleh;
- Metelli, Alessandra;
- Riesenberg, Brian;
- Wu, Bill X.;
- Nelson, Michelle H.;
- Wallace, Caroline;
- Paulos, Chrystal M.;
- Rubinstein, Mark P.;
- Garrett-Mayer, Elizabeth;
- Hennig, Mirko;
- Bearden, Daniel W.;
- Yi Yang;
- Bei Liu;
- Zihai Li
Publication type:
Article
Resident memory T cells in the skin mediate durable immunity to melanoma.
Published in:
Science Immunology, 2017, v. 2, n. 10, p. 1, doi. 10.1126/sciimmunol.aam6346
By:
- Malik, Brian T.;
- Byrne, Katelyn T.;
- Vella, Jennifer L.;
- Peisheng Zhang;
- Shabaneh, Tamer B.;
- Steinberg, Shannon M.;
- Molodtsov, Aleksey K.;
- Bowers, Jacob S.;
- Angeles, Christina V.;
- Paulos, Chrystal M.;
- Huang, Yina H.;
- Turk, Mary Jo
Publication type:
Article
Strategies to Overcome Failures in T-Cell Immunotherapies by Targeting PI3K-δ and –γ.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.718621
By:
- Chandrasekaran, Sanjay;
- Funk, Christopher Ronald;
- Kleber, Troy;
- Paulos, Chrystal M.;
- Shanmugam, Mala;
- Waller, Edmund K.
Publication type:
Article
Fundamentals of T Cell Metabolism and Strategies to Enhance Cancer Immunotherapy.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.645242
By:
- Rangel Rivera, Guillermo O.;
- Knochelmann, Hannah M.;
- Dwyer, Connor J.;
- Smith, Aubrey S.;
- Wyatt, Megan M.;
- Rivera-Reyes, Amalia M.;
- Thaxton, Jessica E.;
- Paulos, Chrystal M.
Publication type:
Article
IL-2Rα mediates temporal regulation of IL-2 signaling and enhances immunotherapy.
Published in:
Science Translational Medicine, 2015, v. 7, n. 311, p. 1, doi. 10.1126/scitranslmed.aac8155
By:
- Su, Ee W.;
- Moore, Caitlin J.;
- Suriano, Samantha;
- Johnson, Christopher Bryce;
- Songalia, Neizel;
- Patterson, Alicia;
- Neitzke, Daniel J.;
- Andrijauskaite, Kristina;
- Garrett-Mayer, Elizabeth;
- Mehrotra, Shikhar;
- Paulos, Chrystal M.;
- Doedens, Andrew L.;
- Goldrath, Ananda W.;
- Zihai Li;
- Cole, David J.;
- Rubinstein, Mark P.
Publication type:
Article
Perspectives in immunotherapy: meeting report from the immunotherapy bridge (December 2nd-3rd, 2020, Italy).
Published in:
2021
By:
- Ascierto, Paolo A.;
- Bifulco, Carlo;
- Ciardiello, Fortunato;
- Demaria, Sandra;
- Emens, Leisha A.;
- Ferris, Robert;
- Formenti, Silvia C.;
- Galon, Jerome;
- Khleif, Samir N.;
- Kirchhoff, Tomas;
- McQuade, Jennifer;
- Odunsi, Kunle;
- Patnaik, Akash;
- Paulos, Chrystal M.;
- Taube, Janis M.;
- Timmerman, John;
- Fox, Bernard A.;
- Hwu, Patrick;
- Puzanov, Igor
Publication type:
journal article
Perspectives in immunotherapy: meeting report from the "Immunotherapy Bridge" (December 4th-5th, 2019, Naples, Italy).
Published in:
2021
By:
- Ascierto, Paolo A.;
- Butterfield, Lisa H.;
- Campbell, Katie;
- Daniele, Bruno;
- Dougan, Michael;
- Emens, Leisha A.;
- Formenti, Silvia;
- Janku, Filip;
- Khleif, Samir N.;
- Kirchhoff, Tomas;
- Morabito, Alessandro;
- Najjar, Yana;
- Nathan, Paul;
- Odunsi, Kunle;
- Patnaik, Akash;
- Paulos, Chrystal M.;
- Reinfeld, Bradley I.;
- Skinner, Heath D.;
- Timmerman, John;
- Puzanov, Igor
Publication type:
journal article
Impact of nodal status in determining multimodal treatment strategies in non‐cardia gastric cancer.
Published in:
Journal of Surgical Oncology, 2023, v. 128, n. 2, p. 242, doi. 10.1002/jso.27297
By:
- Ajay, Pranay S.;
- Sok, Caitlin P.;
- Goyal, Subir;
- Switchenko, Jeffery M.;
- Maegawa, Felipe B.;
- Gillespie, Theresa W.;
- Paulos, Chrystal M.;
- Lesinski, Gregory B.;
- Kooby, David A.;
- Kennedy, Timothy J.;
- Shah, Mihir M.
Publication type:
Article
Does non‐metastatic gastric cancer of the cardia warrant a different treatment strategy?
Published in:
Journal of Surgical Oncology, 2023, v. 128, n. 2, p. 231, doi. 10.1002/jso.27276
By:
- Ajay, Pranay S.;
- NeMoyer, Rachel;
- Goyal, Subir;
- Switchenko, Jeffery M.;
- Lin, Yong;
- Jabbour, Salma K.;
- Carpizo, Darren R.;
- Paulos, Chrystal M.;
- Kennedy, Timothy J.;
- Shah, Mihir M.
Publication type:
Article
The evolving landscape of immunotherapy in solid tumors.
Published in:
Journal of Surgical Oncology, 2021, v. 123, n. 3, p. 798, doi. 10.1002/jso.26416
By:
- Keilson, Jessica M.;
- Knochelmann, Hannah M.;
- Paulos, Chrystal M.;
- Kudchadkar, Ragini R.;
- Lowe, Michael C.
Publication type:
Article
Cover Image, Volume 123, Number 3, March 1, 2021.
Published in:
Journal of Surgical Oncology, 2021, v. 123, n. 3, p. i, doi. 10.1002/jso.26000
By:
- Keilson, Jessica M.;
- Knochelmann, Hannah M.;
- Paulos, Chrystal M.;
- Kudchadkar, Ragini R.;
- Lowe, Michael C.
Publication type:
Article
Pi3Kδ Inhibition Enhances the Antitumor Fitness of Adoptively Transferred CD8+ T cells.
Published in:
Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01221
By:
- Bowers, Jacob S.;
- Majchrzak, Kinga;
- Nelson, Michelle H.;
- Aksoy, Bulent Arman;
- Wyatt, Megan M.;
- Smith, Aubrey S.;
- Bailey, Stefanie R.;
- Neal, Lillian R.;
- Hammerbacher, Jeffrey E.;
- Paulos, Chrystal M.
Publication type:
Article
The Inducible Costimulator (ICOS) Is Critical for the Development of Human TH17 Cells.
Published in:
Science Translational Medicine, 2010, v. 2, n. 55, p. 1, doi. 10.1126/scitranslmed.3000448
By:
- Paulos, Chrystal M.;
- Carpenito, Carmine;
- Plesa, Gabriela;
- Suhoski, Megan M.;
- Varela-Rohena, Angel;
- Golovina, Tatiana N.;
- Carroll, Richard G.;
- Riley, James L.;
- June, Carl H.
Publication type:
Article
Human CD26high T cells elicit tumor immunity against multiple malignancies via enhanced migration and persistence.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01867-9
By:
- Bailey, Stefanie R.;
- Nelson, Michelle H.;
- Majchrzak, Kinga;
- Bowers, Jacob S.;
- Wyatt, Megan M.;
- Smith, Aubrey S.;
- Neal, Lillian R.;
- Shirai, Keisuke;
- Carpenito, Carmine;
- June, Carl H.;
- Zilliox, Michael J.;
- Paulos, Chrystal M.
Publication type:
Article
Vaccination with poly(IC:LC) and peptide-pulsed autologous dendritic cells in patients with pancreatic cancer.
Published in:
Journal of Hematology & Oncology, 2017, v. 10, p. 1, doi. 10.1186/s13045-017-0459-2
By:
- Mehrotra, Shikhar;
- Britten, Carolyn D.;
- Chin, Steve;
- Garrett-Mayer, Elizabeth;
- Cloud, Colleen A.;
- Mingli Li;
- Scurti, Gina;
- Salem, Mohamed L.;
- Nelson, Michelle H.;
- Thomas, Melanie B.;
- Paulos, Chrystal M.;
- Salazar, Andres M.;
- Nishimura, Michael I.;
- Rubinstein, Mark P.;
- Zihai Li;
- Cole, David J.
Publication type:
Article
The clinical implications of immunogenomics in colorectal cancer: A path for precision medicine.
Published in:
2018
By:
- Riley, Jenny M.;
- Cross, Ashley W.;
- Paulos, Chrystal M.;
- Rubinstein, Mark P.;
- Wrangle, John;
- Camp, E. Ramsay
Publication type:
journal article
Fallbericht: Verzögert einsetzende Multi-Organ-Toxizitäten bei einem Melanompatienten, der ein vollständiges Ansprechen auf BRAF/MEK-Hemmung erreicht.
Published in:
Kompass Dermatologie, 2022, v. 10, n. 3, p. 154, doi. 10.1159/000525628
By:
- Knochelmann, Hannah M.;
- Ware, Michael Brandon;
- Rali, Adiiya;
- Lindermann, Susanne;
- Shantha, Jessica G.;
- Lawson, David H.;
- Yushak, Melinda;
- Swerlicke, Robert;
- Paulos, Chrystal M.;
- Yeh, Steven;
- Kudchadkars, Ragini
Publication type:
Article
Case Report: Delayed Onset Multi-Organ Toxicities in a Melanoma Patient Achieving Complete Response to BRAF/MEK Inhibition.
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.836845
By:
- Knochelmann, Hannah M.;
- Ware, Michael Brandon;
- Rali, Aditya;
- Linderman, Susanne;
- Shantha, Jessica G.;
- Lawson, David H.;
- Yushak, Melinda;
- Swerlick, Robert;
- Paulos, Chrystal M.;
- Yeh, Steven;
- Kudchadkar, Ragini
Publication type:
Article
CD8+ T cell-derived Fgl2 regulates immunity in a cell-autonomous manner via ligation of FcγRIIB.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49475-8
By:
- Bennion, Kelsey B.;
- Liu, Danya;
- Dawood, Abdelhameed S.;
- Wyatt, Megan M.;
- Alexander, Katie L.;
- Abdel-Hakeem, Mohamed S.;
- Paulos, Chrystal M.;
- Ford, Mandy L.
Publication type:
Article
FcγRIIB expressed on CD8+ T cells limits responsiveness to PD-1 checkpoint inhibition in cancer.
Published in:
Science Translational Medicine, 2023, v. 15, n. 710, p. 1, doi. 10.1126/scitranslmed.add1868
By:
- Bennion, Kelsey B.;
- Tariq, Marvi;
- Wyatt, Megan M.;
- Duneton, Charlotte;
- Baecher, Kirsten M.;
- Paulos, Chrystal M.;
- Kudchadkar, Ragini R.;
- Lowe, Michael C.;
- Ford, Mandy L.
Publication type:
Article
Molecular properties of gp100‐reactive T‐cell receptors drive the cytokine profile and antitumor efficacy of transgenic host T cells.
Published in:
Pigment Cell & Melanoma Research, 2019, v. 32, n. 1, p. 68, doi. 10.1111/pcmr.12724
By:
- Eby, Jonathan M.;
- Smith, Angela R.;
- Riley, Timothy P.;
- Cosgrove, Cormac;
- Ankney, Christian M.;
- Henning, Steven W.;
- Paulos, Chrystal M.;
- Garrett‐Mayer, Elizabeth;
- Luiten, Rosalie M.;
- Nishimura, Michael I.;
- Baker, Brian M.;
- Le Poole, I. Caroline
Publication type:
Article
Th17 cells in cancer: the ultimate identity crisis.
Published in:
Frontiers in Immunology, 2014, v. 5, p. 1, doi. 10.3389/fimmu.2014.00276
By:
- Bailey, Stefanie R.;
- Nelson, Michelle H.;
- Himes, Richard A.;
- Zihai Li;
- Mehrotra, Shikhar;
- Paulos, Chrystal M.
Publication type:
Article
Th17 cells in cancer: the ultimate identity crisis.
Published in:
Frontiers in Immunology, 2014, v. 5, p. 1, doi. 10.3389/fimmu.2014.00276
By:
- Bailey, Stefanie R.;
- Nelson, Michelle H.;
- Himes, Richard A.;
- Zihai Li;
- Mehrotra, Shikhar;
- Paulos, Chrystal M.
Publication type:
Article

Found: 43