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RAS screening in colorectal cancer: a comprehensive analysis of the results from the UK NEQAS colorectal cancer external quality assurance schemes (2009-2016).
Published in:
2017
By:
- Richman, Susan;
- Fairley, Jennifer;
- Butler, Rachel;
- Deans, Zandra;
- Richman, Susan D;
- Deans, Zandra C
Publication type:
journal article
Prospective patient stratification into robust cancer‐cell intrinsic subtypes from colorectal cancer biopsies.
Published in:
Journal of Pathology, 2018, v. 245, n. 1, p. 19, doi. 10.1002/path.5051
By:
- Alderdice, Matthew;
- Richman, Susan D.;
- Gollins, Simon;
- Stewart, James P.;
- Hurt, Chris;
- Adams, Richard;
- McCorry, Amy M. B.;
- Roddy, Aideen C.;
- Vimalachandran, Dale;
- Isella, Claudio;
- Medico, Enzo;
- Maughan, Tim;
- McArt, Darragh G.;
- Lawler, Mark;
- Dunne, Philip D.
Publication type:
Article
HER2 overexpression and amplification as a potential therapeutic target in colorectal cancer: analysis of 3256 patients enrolled in the QUASAR, FOCUS and PICCOLO colorectal cancer trials.
Published in:
Journal of Pathology, 2016, v. 238, n. 4, p. 562, doi. 10.1002/path.4679
By:
- Richman, Susan D;
- Southward, Katie;
- Chambers, Philip;
- Cross, Debra;
- Barrett, Jennifer;
- Hemmings, Gemma;
- Taylor, Morag;
- Wood, Henry;
- Hutchins, Gordon;
- Foster, Joseph M;
- Oumie, Assa;
- Spink, Karen G;
- Brown, Sarah R;
- Jones, Marc;
- Kerr, David;
- Handley, Kelly;
- Gray, Richard;
- Seymour, Matthew;
- Quirke, Philip
Publication type:
Article
A robust multiplex immunofluorescence and digital pathology workflow for the characterisation of the tumour immune microenvironment.
Published in:
Molecular Oncology, 2020, v. 14, n. 10, p. 2384, doi. 10.1002/1878-0261.12764
By:
- Viratham Pulsawatdi, Amélie;
- Craig, Stephanie G.;
- Bingham, Victoria;
- McCombe, Kris;
- Humphries, Matthew P.;
- Senevirathne, Seedevi;
- Richman, Susan D.;
- Quirke, Phil;
- Campo, Leticia;
- Domingo, Enric;
- Maughan, Timothy S.;
- James, Jacqueline A.;
- Salto‐Tellez, Manuel
Publication type:
Article
Image-based consensus molecular subtyping in rectal cancer biopsies and response to neoadjuvant chemoradiotherapy.
Published in:
NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00580-3
By:
- Lafarge, Maxime W.;
- Domingo, Enric;
- Sirinukunwattana, Korsuk;
- Wood, Ruby;
- Samuel, Leslie;
- Murray, Graeme;
- Richman, Susan D.;
- Blake, Andrew;
- Sebag-Montefiore, David;
- Gollins, Simon;
- Klieser, Eckhard;
- Neureiter, Daniel;
- Huemer, Florian;
- Greil, Richard;
- Dunne, Philip;
- Quirke, Philip;
- Weiss, Lukas;
- Rittscher, Jens;
- Maughan, Tim;
- Koelzer, Viktor H.
Publication type:
Article
Intra-tumoral heterogeneity of KRAS and BRAF mutation status in patients with advanced colorectal cancer (aCRC) and cost-effectiveness of multiple sample testing.
Published in:
Analytical Cellular Pathology: Cellular Oncology, 2011, v. 34, n. 1/2, p. 61, doi. 10.1155/2011/393521
By:
- Richman, Susan D.;
- Chambers, Philip;
- Seymour, Matthew T.;
- Daly, Catherine;
- Grant, Sophie;
- Hemmings, Gemma;
- Quirke, Philip
Publication type:
Article
Confirmation that somatic mutations of beta‐2 microglobulin correlate with a lack of recurrence in a subset of stage II mismatch repair deficient colorectal cancers from the QUASAR trial.
Published in:
Histopathology, 2019, v. 75, n. 2, p. 236, doi. 10.1111/his.13895
By:
- Barrow, Paul;
- Richman, Susan D;
- Wallace, Andrew J;
- Handley, Kelly;
- Hutchins, Gordon G A;
- Kerr, David;
- Magill, Laura;
- Evans, D Gareth;
- Gray, Richard;
- Quirke, Phil;
- Hill, James
Publication type:
Article
Targeted Next-Generation Sequencing Validates the Use of Diagnostic Biopsies as a Suitable Alternative to Resection Material for Mutation Screening in Colorectal Cancer.
Published in:
Molecular Diagnosis & Therapy, 2019, v. 23, n. 3, p. 383, doi. 10.1007/s40291-019-00388-z
By:
- Ham-Karim, Hersh A.;
- Ebili, Henry Okuchukwu;
- Manger, Kirsty;
- Fadhil, Wakkas;
- Ahmad, Narmeen S.;
- Richman, Susan D.;
- Ilyas, Mohammad
Publication type:
Article
Adaptor Template Oligo-Mediated Sequencing (ATOM-Seq) is a new ultra-sensitive UMI-based NGS library preparation technology for use with cfDNA and cfRNA.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-82737-9
By:
- Dunwell, Thomas L.;
- Dailey, Simon C.;
- Ottestad, Anine L.;
- Yu, Jihang;
- Becker, Philipp W.;
- Scaife, Sarah;
- Richman, Susan D.;
- Wood, Henry M.;
- Slaney, Hayley;
- Bottomley, Daniel;
- Yang, Xiangsheng;
- Xiao, Hui;
- Wahl, Sissel G. F.;
- Grønberg, Bjørn H.;
- Dai, Hongyan;
- Fu, Guoliang
Publication type:
Article
Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone.
Published in:
2021
By:
- ten Hoorn, Sanne;
- Sommeijer, Dirkje W.;
- Elliott, Faye;
- Fisher, David;
- de Back, Tim R.;
- Trinh, Anne;
- Koens, Lianne;
- Maughan, Tim;
- Seligmann, Jenny;
- Seymour, Matthew T.;
- Quirke, Phil;
- Adams, Richard;
- Richman, Susan D.;
- Punt, Cornelis J. A.;
- Vermeulen, Louis
Publication type:
journal article
Immune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxia.
Published in:
2020
By:
- Craig, Stephanie G.;
- Humphries, Matthew P.;
- Alderdice, Matthew;
- Bingham, Victoria;
- Richman, Susan D.;
- Loughrey, Maurice B.;
- Coleman, Helen G.;
- Viratham-Pulsawatdi, Amelie;
- McCombe, Kris;
- Murray, Graeme I.;
- Blake, Andrew;
- Domingo, Enric;
- Robineau, James;
- Brown, Louise;
- Fisher, David;
- Seymour, Matthew T.;
- Quirke, Phil;
- Bankhead, Peter;
- McQuaid, Stephen;
- Lawler, Mark
Publication type:
journal article
Molecular selection of therapy in metastatic colorectal cancer: the FOCUS4 molecularly stratified RCT.
Published in:
Efficacy & Mechanism Evaluation (EME), 2022, v. 9, n. 9, p. vii, doi. 10.3310/HTNB6908
By:
- Brown, Louise C.;
- Fisher, David;
- Adams, Richard;
- Seligmann, Jenny;
- Seymour, Matthew;
- Kaplan, Richard;
- Richman, Susan D.;
- Quirke, Philip;
- Butler, Rachel;
- Roberts, Helen;
- Graham, Janet;
- Wilson, Richard H.;
- Maughan, Timothy S.
Publication type:
Article
EGFR Amplification in Metastatic Colorectal Cancer.
Published in:
2021
By:
- Randon, Giovanni;
- Yaeger, Rona;
- Hechtman, Jaclyn F;
- Manca, Paolo;
- Fucà, Giovanni;
- Walch, Henry;
- Lee, Jeeyun;
- Élez, Elena;
- Seligmann, Jenny;
- Mussolin, Benedetta;
- Pagani, Filippo;
- Germani, Marco Maria;
- Ambrosini, Margherita;
- Rossini, Daniele;
- Ratti, Margherita;
- Salvà, Francesc;
- Richman, Susan D;
- Wood, Henry;
- Nanjangud, Gouri;
- Gloghini, Annunziata
Publication type:
journal article
Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer.
Published in:
Clinical Trials, 2022, v. 19, n. 2, p. 146, doi. 10.1177/17407745211069879
By:
- Brown, Louise C;
- Graham, Janet;
- Fisher, David;
- Adams, Richard;
- Seligmann, Jenny;
- Seymour, Matthew;
- Kaplan, Richard;
- Yates, Emma;
- Parmar, Mahesh;
- Richman, Susan D;
- Quirke, Philip;
- Butler, Rachel;
- Shiu, Kaikeen;
- Middleton, Gary;
- Samuel, Leslie;
- Wilson, Richard H;
- Maughan, Timothy S
Publication type:
Article

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