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- Title
Pancreatic intraductal papillary-mucinous neoplasms: a new and evolving entity.
- Authors
Markus Kosmahl; Bence Sipos; Günter Klöppel
- Abstract
Abstract  For a long time, intraductal tumors of the pancreas were neglected because they were misdiagnosed as mucinous cystadenocarcinoma, ordinary ductal adenocarcinoma, or chronic pancreatitis. Only in recent years have they been recognized as clinical and pathological entities. Most common are the intraductal papillary-mucinous neoplasms. Although they show an adenoma-carcinoma sequence, they have proved to have a more favorable prognosis than ductal adenocarcinoma, when resected in a preinvasive state. Recently, it has become clear that they constitute a heterogeneous group with at least four subtypes. Their stratification reveals that the various intraductal papillary-mucinous neoplasm subtypes have different biological properties with different prognostic implications.
- Subjects
TUMORS; PANCREAS; ADENOCARCINOMA; PATHOLOGY
- Publication
Virchows Archiv: European Journal of Pathology, 2007, Vol 451, Issue 5, p863
- ISSN
0945-6317
- Publication type
Article