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- Title
Mid-infrared reflectivity of experimental atheromas.
- Authors
Hoi-Ying N. Holman; Kathy A. Bjornstad; Michael C. Martin; Wayne R. Mckinney; Eleanor A. Blakely; Francis G. Blankenberg
- Abstract
We report that the pathologic components present within the atheromatous plaques of ApoE knock-out mice can reflect significant amounts of mid-infrared (mid-IR) light. Furthermore, the reflected light spectra contained the unique signatures of a variety of biologic features including those found in unstable or “vulnerable” plaque. This discovery may represent a unique opportunity to develop a new intravascular diagnostic modality that can detect and characterize sites of atherosclerosis.
- Subjects
ATHEROSCLEROTIC plaque; REFLECTANCE; ATHEROSCLEROSIS; INTRAVASCULAR ultrasonography
- Publication
Journal of Biomedical Optics, 2008, Vol 13, Issue 3, p30503
- ISSN
1083-3668
- Publication type
Article
- DOI
10.1117/1.2937469