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- Title
Management of posterior inferior cerebellar artery aneurysms: What factors play the most important role in outcome?
- Authors
Sejkorová, Alena; Petr, Ondra; Mulino, Miriam; Cihlář, Jiří; Hejčl, Aleš; Thomé, Claudius; Sameš, Martin; Lanzino, Giuseppe
- Abstract
Background: Posterior inferior cerebellar artery (PICA) aneurysms are an uncommon, heterogeneous group of aneurysms with poorer clinical outcomes compared to other intracranial aneurysms. We performed a multicenter retrospective study to analyze the outcome in a large series of patients treated with modern microsurgical and endovascular techniques. Methods: Records of 94 patients treated for PICA aneurysms between 2000 and 2015 at three large tertiary referral centers were retrospectively reviewed. Results: Eighty-three patients met inclusion criteria and of these, two died before treatment, leaving 81 treated patients (43 underwent endovascular and 38 surgical treatment). Among patients treated endovascularly, procedure-related complications occurred in four cases (11.8%). Six patients (19.4%) suffered from complications directly associated with surgery. Recurrences occurred in 0% of surgical and in 16.3% of endovascularly treated patients, requiring treatment. Patients with unruptured asymptomatic aneurysms had good outcomes. In the group of 67 ruptured aneurysms, 16 endovascularly (47.1%) and 15 surgically (48.4%) treated patients had modified Rankin scale (mRS) scores of 3-6. Of patients in poor neurological condition (Hunt & Hess (H&H) IV-V at admission), 84.6% suffered a poor clinical outcome. Fifty percent of patients with distal and 31.9% patients with proximal ruptured PICA aneurysms suffered a poor neurological outcome. Conclusions: This study of PICA aneurysms demonstrates that results of both treatment modalities are comparable. However, endovascular treatment is associated with higher risks of recurrence, requiring additional treatment. Outcomes were mostly impacted by clinical state at admission.
- Subjects
INTRACRANIAL aneurysms; RETROSPECTIVE studies; ENDOVASCULAR surgery; THERAPEUTIC embolization; SUBARACHNOID hemorrhage; DISEASE risk factors
- Publication
Acta Neurochirurgica, 2017, Vol 159, Issue 3, p549
- ISSN
0001-6268
- Publication type
Article
- DOI
10.1007/s00701-016-3058-z