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The extracellular matrix glycoprotein ADAMTSL2 is increased in heart failure and inhibits TGFβ signalling in cardiac fibroblasts.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-99032-2
By:
- Rypdal, Karoline B.;
- Erusappan, Pugazendhi M.;
- Melleby, A. Olav;
- Seifert, Deborah E.;
- Palmero, Sheryl;
- Strand, Mari E.;
- Tønnessen, Theis;
- Dahl, Christen P.;
- Almaas, Vibeke;
- Hubmacher, Dirk;
- Apte, Suneel S.;
- Christensen, Geir;
- Lunde, Ida G.
Publication type:
Article
Moderate Loss of the Extracellular Matrix Proteoglycan Lumican Attenuates Cardiac Fibrosis in Mice Subjected to Pressure Overload.
Published in:
Cardiology, 2020, v. 145, n. 3, p. 187, doi. 10.1159/000505318
By:
- Mohammadzadeh, Naiyereh;
- Melleby, Arne Olav;
- Palmero, Sheryl;
- Sjaastad, Ivar;
- Chakravarti, Shukti;
- Engebretsen, Kristin V.T.;
- Christensen, Geir;
- Lunde, Ida G.;
- Tønnessen, Theis
Publication type:
Article
Inhibition of the extracellular enzyme A disintegrin and metalloprotease with thrombospondin motif 4 prevents cardiac fibrosis and dysfunction.
Published in:
Cardiovascular Research, 2023, v. 119, n. 10, p. 1915, doi. 10.1093/cvr/cvad078
By:
- Vistnes, Maria;
- Erusappan, Pugazendhi Murugan;
- Sasi, Athiramol;
- Nordén, Einar Sjaastad;
- Bergo, Kaja Knudsen;
- Romaine, Andreas;
- Lunde, Ida Gjervold;
- Zhang, Lili;
- Olsen, Maria Belland;
- Øgaard, Jonas;
- Carlson, Cathrine Rein;
- Wang, Christian Hjorth;
- Riise, Jon;
- Dahl, Christen Peder;
- Fiane, Arnt Eltvedt;
- Hauge-Iversen, Ida Marie;
- Espe, Emil;
- Melleby, Arne Olav;
- Tønnessen, Theis;
- Aronsen, Jan Magnus
Publication type:
Article
CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI: difference from BNP visualized by targeted cGMP biosensors.
Published in:
Cardiovascular Research, 2022, v. 118, n. 6, p. 1506, doi. 10.1093/cvr/cvab167
By:
- Manfra, Ornella;
- Calamera, Gaia;
- Froese, Alexander;
- Arunthavarajah, Dulasi;
- Surdo, Nicoletta C;
- Meier, Silja;
- Melleby, Arne Olav;
- Aasrum, Monica;
- Aronsen, Jan Magnus;
- Nikolaev, Viacheslav O;
- Zaccolo, Manuela;
- Moltzau, Lise Román;
- Levy, Finn Olav;
- Andressen, Kjetil Wessel
Publication type:
Article
Regulation of cardiomyocyte t‐tubule structure by preload and afterload: Roles in cardiac compensation and decompensation.
Published in:
Journal of Physiology, 2024, v. 602, n. 18, p. 4487, doi. 10.1113/JP284566
By:
- Ruud, Marianne;
- Frisk, Michael;
- Melleby, Arne Olav;
- Norseng, Per Andreas;
- Mohamed, Belal A.;
- Li, Jia;
- Aronsen, Jan Magnus;
- Setterberg, Ingunn E.;
- Jakubiczka, Joanna;
- van Hout, Isabelle;
- Coffey, Sean;
- Shen, Xin;
- Nygård, Ståle;
- Lunde, Ida G.;
- Tønnessen, Theis;
- Jones, Peter P.;
- Sjaastad, Ivar;
- Gullestad, Lars;
- Toischer, Karl;
- Dahl, Cristen P.
Publication type:
Article
Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin.
Published in:
2020
By:
- Herum, Kate M;
- Romaine, Andreas;
- Wang, Ariel;
- Melleby, Arne Olav;
- Strand, Mari E;
- Pacheco, Julian;
- Braathen, Bjørn;
- Dunér, Pontus;
- Tønnessen, Theis;
- Lunde, Ida G;
- Sjaastad, Ivar;
- Brakebusch, Cord;
- McCulloch, Andrew D;
- Gomez, Maria F;
- Carlson, Cathrine R;
- Christensen, Geir
Publication type:
journal article
Impact of delayed type hypersensitivity arthritis on development of heart failure by aortic constriction in mice.
Published in:
PLoS ONE, 2022, v. 17, n. 1, p. 1, doi. 10.1371/journal.pone.0262821
By:
- Tønnessen, Theis Christian;
- Melleby, Arne Olav;
- Hauge-Iversen, Ida Marie;
- Espe, Emil Knut Stenersen;
- Ahmed, Mohammed Shakil;
- Ueland, Thor;
- Haavardsholm, Espen Andre;
- Atkinson, Sara Marie;
- Melum, Espen;
- Attramadal, Håvard;
- Sjaastad, Ivar;
- Vinge, Leif Erik
Publication type:
Article
Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy.
Published in:
Molecular Biology Reports, 2022, v. 49, n. 12, p. 11795, doi. 10.1007/s11033-022-07985-y
By:
- Lunde, Ida G.;
- Aronsen, J. Magnus;
- Melleby, A. Olav;
- Strand, Mari E.;
- Skogestad, Jonas;
- Bendiksen, Bård A.;
- Ahmed, M. Shakil;
- Sjaastad, Ivar;
- Attramadal, Håvard;
- Carlson, Cathrine R.;
- Christensen, Geir
Publication type:
Article
ADAMTSL3 knock-out mice develop cardiac dysfunction and dilatation with increased TGFβ signalling after pressure overload.
Published in:
Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-04361-1
By:
- Rypdal, Karoline B.;
- Olav Melleby, A.;
- Robinson, Emma L.;
- Li, Jia;
- Palmero, Sheryl;
- Seifert, Deborah E.;
- Martin, Daniel;
- Clark, Catelyn;
- López, Begoña;
- Andreassen, Kristine;
- Dahl, Christen P.;
- Sjaastad, Ivar;
- Tønnessen, Theis;
- Stokke, Mathis K.;
- Louch, William E.;
- González, Arantxa;
- Heymans, Stephane;
- Christensen, Geir;
- Apte, Suneel S.;
- Lunde, Ida G.
Publication type:
Article

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