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- Title
Medical management of hepatorenal syndrome.
- Authors
Davenport, Andrew; Ahmad, Jawad; Al-Khafaji, Ali; Kellum, John A.; Genyk, Yuri S.; Nadim, Mitra K.
- Abstract
Hepatorenal syndrome (HRS) is defined as the occurrence of renal dysfunction in a patient with end-stage liver cirrhosis in the absence of another identifiable cause of renal failure. The prognosis of HRS remains poor, with a median survival without liver transplantation of <6 months. However, understanding the pathogenesis of HRS has led to the introduction of treatments designed to increase renal perfusion and mean arterial blood pressure using vasopressors and albumin, which has led to improvement in renal function in ∼50% of patients.
- Subjects
HEPATORENAL syndrome; CIRRHOSIS of the liver; KIDNEY failure; LIVER transplantation; PERFUSION; BLOOD pressure; ALBUMINS; PATIENTS; THERAPEUTICS
- Publication
Nephrology Dialysis Transplantation, 2012, Vol 27, Issue 1, p34
- ISSN
0931-0509
- Publication type
Article
- DOI
10.1093/ndt/gfr736