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Induction of sustained remission in early inflammatory arthritis with the combination of infliximab plus methotrexate: the DINORA trial.
Published in:
Arthritis Research & Therapy, 2018, v. 20, n. 1, p. N.PAG, doi. 10.1186/s13075-018-1667-z
By:
- Stamm, Tanja Alexandra;
- Machold, Klaus Peter;
- Aletaha, Daniel;
- Alasti, Farideh;
- Lipsky, Peter;
- Pisetsky, David;
- Landewe, Robert;
- van der Heijde, Desiree;
- Sepriano, Alexandre;
- Aringer, Martin;
- Boumpas, Dimitri;
- Burmester, Gerd;
- Cutolo, Maurizio;
- Ebner, Wolfgang;
- Graninger, Winfried;
- Huizinga, Tom;
- Schett, Georg;
- Schulze-Koops, Hendrik;
- Tak, Paul-Peter;
- Martin-Mola, Emilio
Publication type:
Article
B-cell imaging with zirconium-89 labelled rituximab PET-CT at baseline is associated with therapeutic response 24 weeks after initiation of rituximab treatment in rheumatoid arthritis patients.
Published in:
Arthritis Research & Therapy, 2016, v. 18, p. 1, doi. 10.1186/s13075-016-1166-z
By:
- Bruijnen, Stefan;
- Tsang-A-Sjoe, Michel;
- Raterman, Hennie;
- Ramwadhdoebe, Tamara;
- Vugts, Daniëlle;
- van Dongen, Guus;
- Huisman, Marc;
- Hoekstra, Otto;
- Tak, Paul-Peter;
- Voskuyl, Alexandre;
- van der Laken, Conny
Publication type:
Article
MiR-146a G/C rs2910164 variation in South African Indian and Caucasian patients with psoriatic arthritis.
Published in:
BMC Medical Genetics, 2018, v. 19, p. 1, doi. 10.1186/s12881-018-0565-1
By:
- Maharaj, Ajesh B.;
- Naidoo, Pragalathan;
- Ghazi, Terisha;
- Abdul, Naeem S.;
- Dhani, Shanel;
- Docrat, Taskeen F.;
- Ramkaran, Prithiksha;
- Tak, Paul-Peter;
- de Vries, Niek;
- Chuturgoon, Anil A.
Publication type:
Article
Expression of Prostaglandin E<sub>2</sub> Enzymes in the Synovium of Arthralgia Patients at Risk of Developing Rheumatoid Arthritis and in Early Arthritis Patients.
Published in:
PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0133669
By:
- de Hair, Maria J. H.;
- Leclerc, Patrick;
- Newsum, Elize C.;
- Maijer, Karen I.;
- van de Sande, Marleen G. H.;
- Ramwadhdoebe, Tamara H.;
- van Schaardenburg, Dirkjan;
- van Baarsen, Lisa G. M.;
- Korotkova, Marina;
- Gerlag, Danielle M.;
- Tak, Paul-Peter;
- Jakobsson, Per-Johan
Publication type:
Article
Neurostimulation of the Cholinergic Anti-Inflammatory Pathway Ameliorates Disease in Rat Collagen-Induced Arthritis.
Published in:
PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0104530
By:
- Levine, Yaakov A.;
- Koopman, Frieda A.;
- Faltys, Michael;
- Caravaca, April;
- Bendele, Alison;
- Zitnik, Ralph;
- Vervoordeldonk, Margriet J.;
- Tak, Paul Peter
Publication type:
Article
Prostaglandin E<sub>2</sub> Synthesizing Enzymes in Rheumatoid Arthritis B Cells and the Effects of B Cell Depleting Therapy on Enzyme Expression.
Published in:
PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0016378
By:
- Gheorghe, Karina Roxana;
- Thurlings, Rogier M.;
- Westman, Marie;
- Boumans, Maartje J.;
- Malmström, Vivianne;
- Trollmo, Christina;
- Korotkova, Marina;
- Jakobsson, Per-Johan;
- Tak, Paul-Peter
Publication type:
Article
FMS-related tyrosine kinase 3 ligand (Flt3L)/CD135 axis in rheumatoid arthritis.
Published in:
Arthritis Research & Therapy, 2013, v. 15, n. 6, p. 1, doi. 10.1186/ar4403
By:
- Ramos, Maria I.;
- Garcia Perez, Samuel;
- Aarrass, Saida;
- Helder, Boy;
- Broekstra, Pleun;
- Gerlag, Daan M.;
- Reedquist, Kris A.;
- Tak, Paul Peter;
- Lebre, Maria C.
Publication type:
Article
Change in CD3 positive T-cell expression in psoriatic arthritis synovium correlates with change in DAS28 and magnetic resonance imaging synovitis scores following initiation of biologic therapy-a single centre, open-label study.
Published in:
Arthritis Research & Therapy, 2011, v. 13, n. 1, p. 1, doi. 10.1186/ar3228
By:
- Pontifex, Eliza K.;
- Gerlag, Danielle M.;
- Gogarty, Martina;
- Vinkenoog, Marjolein;
- Gibbs, Adrian;
- Burgman, Ilse;
- Fearon, Ursula;
- Bresnihan, Barry;
- Tak, Paul Peter;
- Gibney, Robin G.;
- Veale, Douglas J.;
- FitzGerald, Oliver
Publication type:
Article
Evaluation of Minimally Invasive, Ultrasound-guided Synovial Biopsy Techniques by the OMERACT Filter--Determining Validation Requirements.
Published in:
2016
By:
- Humby, Frances;
- Kelly, Stephen;
- Bugatti, Serena;
- Manzo, Antonio;
- Filer, Andrew;
- Mahto, Arti;
- Fonseca, Joao Eurico;
- Lauwerys, Bernard;
- D'Agostino, Maria-Antonietta;
- Naredo, Esperanza;
- Lories, Rik;
- Montecucco, Carlomaurizio;
- Tak, Paul Peter;
- Fitzgerald, Oliver;
- Smith, Malcolm D.;
- Veale, Douglas J.;
- Choy, Ernest H.;
- Strand, Vibeke;
- Pitzalis, Costantino
Publication type:
journal article
The prolactin receptor is expressed in rheumatoid arthritis and psoriatic arthritis synovial tissue and contributes to macrophage activation.
Published in:
Rheumatology, 2016, v. 55, n. 12, p. 2246, doi. 10.1093/rheumatology/kew316
By:
- Man Wai Tang;
- Reedquist, Kris A.;
- Garcia, Samuel;
- Malvar Fernandez, Bea;
- Codullo, Veronica;
- Vieira-Sousa, Elsa;
- Goffin, Vincent;
- Reuwer, Anne Q.;
- Twickler, Marcel T.;
- Gerlag, Daniëlle M.;
- Tak, Paul-Peter
Publication type:
Article
Altered BANK1 expression is not associated with humoral autoimmunity in chronic joint inflammation.
Published in:
2013
By:
- Cantaert, Tineke;
- Yeremenko, Natalyia G.;
- Teitsma, Christine A.;
- van Duivenvoorde, Leonie M.;
- Paramarta, Jackeline E.;
- Tak, Paul-Peter;
- Baeten, Dominique L.
Publication type:
Journal Article
Altered BANK1 expression is not associated with humoral autoimmunity in chronic joint inflammation.
Published in:
Rheumatology, 2013, v. 52, n. 2, p. 252, doi. 10.1093/rheumatology/kes247
By:
- Cantaert, Tineke;
- Yeremenko, Natalyia G.;
- Teitsma, Christine A.;
- Van Duivenvoorde, Leonie M.;
- Paramarta, Jackeline E.;
- Tak, Paul-Peter;
- Baeten, Dominique L.
Publication type:
Article
Response to Inhibition of Receptor‐Interacting Protein Kinase 1 (RIPK1) in Active Plaque Psoriasis: A Randomized Placebo‐Controlled Study.
Published in:
Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 4, p. 808, doi. 10.1002/cpt.1852
By:
- Weisel, Kathleen;
- Berger, Scott;
- Papp, Kim;
- Maari, Catherine;
- Krueger, James G.;
- Scott, Nicola;
- Tompson, Debra;
- Wang, Susanne;
- Simeoni, Monica;
- Bertin, John;
- Peter Tak, Paul
Publication type:
Article
Neo-Epitopes—Fragments of Cartilage and Connective Tissue Degradation in Early Rheumatoid Arthritis and Unclassified Arthritis.
Published in:
PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0149329
By:
- Maijer, Karen I.;
- Gudmann, Natasja Stæhr;
- Karsdal, Morten Asser;
- Gerlag, Daniëlle M.;
- Tak, Paul Peter;
- Bay-Jensen, Anne Christine;
- Pietropaolo, Massimo
Publication type:
Article
Rheumatoid arthritis and psoriatic arthritis synovial fluids stimulate prolactin production by macrophages.
Published in:
Journal of Leukocyte Biology, 2017, v. 102, n. 3, p. 897, doi. 10.1189/jlb.2A0317-115RR
By:
- Tang, Man Wai;
- Garcia, Samuel;
- Malvar Fernandez, Beatriz;
- Gerlag, Danielle M.;
- Tak, Paul‐Peter;
- Reedquist, Kris A.
Publication type:
Article
Relative overexpression of membrane-bound versus soluble TNF in spondyloarthritis.
Published in:
2012
By:
- Ambarus, Carmen A.;
- van Duivenvoorde, Leonie M.;
- Masdar, Huriatul;
- van Tok, Melissa N.;
- Tak, Paul-Peter;
- Yeremenko, Nataliya G.;
- Baeten, Dominique L.
Publication type:
Abstract
Extrathymic Autoimmune Regulator (AIRE) expression in rheumatoid arthritis.
Published in:
2012
By:
- Noort, Ae-Ri;
- van Zoest, Katinka P. M.;
- Lebre, M. Christina;
- Tak, Paul-Peter;
- Tas, Sander W.
Publication type:
Abstract
The role of Bob1 in rheumatoid arthritis: potential implications for autoimmunity.
Published in:
2012
By:
- Yeremenko, Nataliya;
- Cantaert, Tineke;
- van Tok, Melissa N.;
- Gofita, Ioana;
- Canete, Juan D.;
- Tak, Paul-Peter;
- Spits, Hergen;
- Baeten, Dominique L.
Publication type:
Abstract
NF-kappaB inducing kinase (NIK) is a key regulator of inflammation-induced angiogenesis.
Published in:
Journal of Translational Medicine, 2012, v. 10, n. Suppl 3, p. 1, doi. 10.1186/1479-5876-10-S3-O1
By:
- Noort, Ae-Ri;
- van Zoest, Katinka P. M.;
- Koolwjk, Pieter;
- Tak, Paul-Peter;
- Tas, Sander W.
Publication type:
Article
Triggering of viral RNA sensors induces CD55 expression on synovial fibroblasts.
Published in:
2011
By:
- Karpus, Olga N.;
- Heutinck, Kirstin M.;
- Wijnker, Paul J. M.;
- Tak, Paul Peter;
- Hamann, Jorg
Publication type:
Abstract
Non-canonical NF-κB signaling in endothelial cells may enhance synovial inflammation by stimulating angiogenesis.
Published in:
2011
By:
- Noort, Ae-Ri;
- van Zoest, Katinka P. M.;
- Tak, Paul Peter;
- Tas, Sander W.
Publication type:
Abstract
Flt3 inhibition leads to decreased production of IL-6 by synovial biopsies and fibroblast-like synoviocytes by reducing NFKb activity.
Published in:
2011
By:
- Inês Ramos, M.;
- Korchynskyi, Olexandr;
- Aarrass, Saida;
- Tak, Paul Peter;
- Cristina Lebre, M.
Publication type:
Abstract
IL-17 producing mast cells contribute to synovial inflammation in non-psoriatic and psoriatic spondyloarthritis.
Published in:
2011
By:
- Noordenbos, Troy;
- Yeremenko, Nataliya;
- Gofita, Ioana;
- Tak, Paul Peter;
- Cañete, Juan;
- Baeten, Dominique
Publication type:
Abstract
Serum biomarkers to predict clinical response in proof-of-concept trials in spondyloarthritis.
Published in:
2011
By:
- Turina, Maureen;
- Yeremenko, Nataliya;
- Paramarta, Jacqueline;
- Vandooren, Bernard;
- Tak, Paul Peter;
- De Rycke, Leen;
- Baeten, Dominique
Publication type:
Abstract
Immune complexes shift the TLR-induced cytokine production of distinct polarized human macrophage subsets towards IL-10.
Published in:
2011
By:
- Ambarus, Carmen;
- Geurts-van Bon, Lenny;
- Wenink, Mark;
- Tak, Paul Peter;
- Radstake, Timothy;
- Baeten, Dominique
Publication type:
Abstract
Identification of robust and disease-specific stromal alterations in spondyloarthritis synovitis.
Published in:
2011
By:
- Yeremenko, Nataliya;
- Noordenbos, Troy;
- Rigter, Gemma;
- Cañete, Juan;
- Tak, Paul-Peter;
- Baeten, Dominique
Publication type:
Abstract
1067. Amelioration of Arthritis after Local Delivery of an Adeno-Associated Virus Type 6 Expressing a TNF-Blocking Agent under a Disease-Inducible Promoter.
Published in:
Molecular Therapy, 2006, v. 13, p. S409, doi. 10.1016/j.ymthe.2006.08.1165
By:
- Khoury, Maroun;
- Adriaansen, Jan;
- Louis-Plence, Pascale;
- Noel, Danièle;
- Bigey, Pascal;
- de Cortie, C.;
- Gould, David;
- Vervoordeldonk, Margriet;
- Scherman, Daniel;
- Tak, Paul-Peter;
- Jorgensen, Christian;
- Apparailly, Florence
Publication type:
Article
DNA Methylome Signature in Synoviocytes From Patients With Early Rheumatoid Arthritis Compared to Synoviocytes From Patients With Longstanding Rheumatoid Arthritis.
Published in:
Arthritis & Rheumatology, 2015, v. 67, n. 7, p. 1978, doi. 10.1002/art.39123
By:
- Ai, Rizi;
- Whitaker, John W.;
- Boyle, David L.;
- Tak, Paul Peter;
- Gerlag, Danielle M.;
- Wang, Wei;
- Firestein, Gary S.
Publication type:
Article
A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus.
Published in:
PLoS Genetics, 2011, v. 7, n. 6, p. 1, doi. 10.1371/journal.pgen.1002128
By:
- Xiaobing Luo;
- Wanling Yang;
- Dong-Qing Ye;
- Huijuan Cui;
- Yan Zhang;
- Nattiya Hirankarn;
- Xiaoxia Qian;
- Yuanjia Tang;
- Yu Lung Lau;
- De Vries, Niek;
- Tak, Paul Peter;
- Tsao, Betty P.;
- Nan Shen
Publication type:
Article
A randomized, placebo-controlled experimental medicine study of RIPK1 inhibitor GSK2982772 in patients with moderate to severe rheumatoid arthritis.
Published in:
Arthritis Research & Therapy, 2021, v. 23, n. 1, p. 1, doi. 10.1186/s13075-021-02468-0
By:
- Weisel, Kathleen;
- Berger, Scott;
- Thorn, Katie;
- Taylor, Peter C.;
- Peterfy, Charles;
- Siddall, Hilary;
- Tompson, Debra;
- Wang, Susanne;
- Quattrocchi, Emilia;
- Burriss, Susan W.;
- Walter, Jochen;
- Tak, Paul Peter
Publication type:
Article
Intrinsic healing response of the human anterior cruciate ligament: An histological study of reattached ACL remnants.
Published in:
Journal of Orthopaedic Research, 2014, v. 32, n. 2, p. 296, doi. 10.1002/jor.22511
By:
- Nguyen, Duy Tan;
- Ramwadhdoebe, Tamara H.;
- van der Hart, Cor P.;
- Blankevoort, Leendert;
- Tak, Paul Peter;
- van Dijk, Cornelis Niek
Publication type:
Article

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