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A Novel Formulation of Tigecycline Has Enhanced Stability and Sustained Antibacterial and Antileukemic Activity.
Published in:
PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0095281
By:
- Jitkova, Yulia;
- Gronda, Marcela;
- Hurren, Rose;
- Wang, Xiaoming;
- Goard, Carolyn A.;
- Jhas, Bozhena;
- Schimmer, Aaron D.
Publication type:
Article
A Porphodimethene Chemical Inhibitor of Uroporphyrinogen Decarboxylase.
Published in:
PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0089889
By:
- Yip, Kenneth W.;
- Zhang, Zhan;
- Sakemura-Nakatsugawa, Noriko;
- Huang, Jui-Wen;
- Vu, Nhu Mai;
- Chiang, Yi-Kun;
- Lin, Chih-Lung;
- Kwan, Jennifer Y. Y.;
- Yue, Shijun;
- Jitkova, Yulia;
- To, Terence;
- Zahedi, Payam;
- Pai, Emil F.;
- Schimmer, Aaron D.;
- Lovell, Jonathan F.;
- Sessler, Jonathan L.;
- Liu, Fei-Fei
Publication type:
Article
Metabolic Adaptation to Chronic Inhibition of Mitochondrial Protein Synthesis in Acute Myeloid Leukemia Cells.
Published in:
PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058367
By:
- Jhas, Bozhena;
- Sriskanthadevan, Shrivani;
- Skrtic, Marko;
- Sukhai, Mahadeo A.;
- Voisin, Veronique;
- Jitkova, Yulia;
- Gronda, Marcela;
- Hurren, Rose;
- Laister, Rob C.;
- Bader, Gary D.;
- Minden, Mark D.;
- Schimmer, Aaron D.
Publication type:
Article
A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia.
Published in:
Cancer Medicine, 2016, v. 5, n. 11, p. 3031, doi. 10.1002/cam4.845
By:
- Reed, Gregory A.;
- Schiller, Gary J.;
- Kambhampati, Suman;
- Tallman, Martin S.;
- Douer, Dan;
- Minden, Mark D.;
- Yee, Karen W.;
- Gupta, Vikas;
- Brandwein, Joseph;
- Jitkova, Yulia;
- Gronda, Marcela;
- Hurren, Rose;
- Shamas ‐ Din, Aisha;
- Schuh, Andre C.;
- Schimmer, Aaron D.
Publication type:
Article
A Phase I Study of the Metal Ionophore Clioquinol in Patients With Advanced Hematologic Malignancies.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2012, v. 12, n. 5, p. 330, doi. 10.1016/j.clml.2012.05.005
By:
- Schimmer, Aaron D.;
- Jitkova, Yulia;
- Gronda, Marcela;
- Zezhou Wang;
- Brandwein, Joseph;
- Chen, Christine;
- Gupta, Vikas;
- Schuh, Andre;
- Yee, Karen;
- Chen, Jian;
- Ackloo, Suzanne;
- Booth, Tristan;
- Keays, Sharon;
- Minden, Mark D.
Publication type:
Article
The mitochondrial peptidase, neurolysin, regulates respiratory chain supercomplex formation and is necessary for AML viability.
Published in:
Science Translational Medicine, 2020, v. 12, n. 538, p. 1, doi. 10.1126/scitranslmed.aaz8264
By:
- Mirali, Sara;
- Botham, Aaron;
- Voisin, Veronique;
- Xu, Changjiang;
- St-Germain, Jonathan;
- Sharon, David;
- Hoff, Fieke W.;
- Qiu, Yihua;
- Hurren, Rose;
- Gronda, Marcela;
- Jitkova, Yulia;
- Nachmias, Boaz;
- MacLean, Neil;
- Wang, Xiaoming;
- Arruda, Andrea;
- Minden, Mark D.;
- Horton, Terzah M.;
- Kornblau, Steven M.;
- Chan, Steven M.;
- Bader, Gary D.
Publication type:
Article
Oral ciclopirox olamine displays biological activity in a phase I study in patients with advanced hematologic malignancies.
Published in:
American Journal of Hematology, 2014, v. 89, n. 4, p. 363, doi. 10.1002/ajh.23640
By:
- Minden, Mark D.;
- Hogge, Donna E.;
- Weir, Scott J.;
- Kasper, Jim;
- Webster, Debra A.;
- Patton, Lavonne;
- Jitkova, Yulia;
- Hurren, Rose;
- Gronda, Marcela;
- Goard, Carolyn A.;
- Rajewski, Lian G.;
- Haslam, John L.;
- Heppert, Kathleen E.;
- Schorno, Kevin;
- Chang, Hong;
- Brandwein, Joseph M.;
- Gupta, Vikas;
- Schuh, Andre C.;
- Trudel, Suzanne;
- Yee, Karen W. L.
Publication type:
Article
Carnitine transporter CT2 (SLC22A16) is over-expressed in acute myeloid leukemia (AML) and target knockdown reduces growth and viability of AML cells.
Published in:
Apoptosis, 2015, v. 20, n. 8, p. 1099, doi. 10.1007/s10495-015-1137-x
By:
- Wu, Yan;
- Hurren, Rose;
- MacLean, Neil;
- Gronda, Marcela;
- Jitkova, Yulia;
- Sukhai, Mahadeo;
- Minden, Mark;
- Schimmer, Aaron
Publication type:
Article
Correction: Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia.
Published in:
2022
By:
- Zhang, Qi;
- Riley-Gillis, Bridget;
- Han, Lina;
- Jia, Yannan;
- Lodi, Alessia;
- Zhang, Haijiao;
- Ganesan, Saravanan;
- Pan, Rongqing;
- Konoplev, Sergej N.;
- Sweeney, Shannon R.;
- Ryan, Jeremy A.;
- Jitkova, Yulia;
- Dunner Jr, Kenneth;
- Grosskurth, Shaun E.;
- Vijay, Priyanka;
- Ghosh, Sujana;
- Lu, Charles;
- Ma, Wencai;
- Kurtz, Stephen;
- Ruvolo, Vivian R.
Publication type:
Correction Notice
Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia.
Published in:
Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-021-00870-3
By:
- Zhang, Qi;
- Riley-Gillis, Bridget;
- Han, Lina;
- Jia, Yannan;
- Lodi, Alessia;
- Zhang, Haijiao;
- Ganesan, Saravanan;
- Pan, Rongqing;
- Konoplev, Sergej N.;
- Sweeney, Shannon R.;
- Ryan, Jeremy A.;
- Jitkova, Yulia;
- Dunner Jr, Kenneth;
- Grosskurth, Shaun E.;
- Vijay, Priyanka;
- Ghosh, Sujana;
- Lu, Charles;
- Ma, Wencai;
- Kurtz, Stephen;
- Ruvolo, Vivian R.
Publication type:
Article
Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia.
Published in:
Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-021-00870-3
By:
- Zhang, Qi;
- Riley-Gillis, Bridget;
- Han, Lina;
- Jia, Yannan;
- Lodi, Alessia;
- Zhang, Haijiao;
- Ganesan, Saravanan;
- Pan, Rongqing;
- Konoplev, Sergej N.;
- Sweeney, Shannon R.;
- Ryan, Jeremy A.;
- Jitkova, Yulia;
- Dunner Jr, Kenneth;
- Grosskurth, Shaun E.;
- Vijay, Priyanka;
- Ghosh, Sujana;
- Lu, Charles;
- Ma, Wencai;
- Kurtz, Stephen;
- Ruvolo, Vivian R.
Publication type:
Article
Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia.
Published in:
Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-021-00870-3
By:
- Zhang, Qi;
- Riley-Gillis, Bridget;
- Han, Lina;
- Jia, Yanan;
- Lodi, Alessia;
- Zhang, Haijiao;
- Ganesan, Saravanan;
- Pan, Rongqing;
- Konoplev, Sergej N.;
- Sweeney, Shannon R.;
- Ryan, Jeremy A.;
- Jitkova, Yulia;
- Dunner Jr, Kenneth;
- Grosskurth, Shaun E.;
- Vijay, Priyanka;
- Ghosh, Sujana;
- Lu, Charles;
- Ma, Wencai;
- Kurtz, Stephen;
- Ruvolo, Vivian R.
Publication type:
Article

Found: 12