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- Title
Editorial: Calcium: An Overview From Physiology to Pathological Mineralization.
- Authors
Zhukouskaya, Volha V.; Bardet, Claire
- Abstract
Calcium, together with phosphate, also participates in the mineralization of calcified tissues where bones act as calcium storage site, intimately linked with the preservation of calcium balance within the non-bone tissues of the body. Keywords: calcium; vitamin D; parathyroid hormone; kidney; dental fluorosis; denosumab; ectopic mineralization; enamel renal syndrome EN calcium vitamin D parathyroid hormone kidney dental fluorosis denosumab ectopic mineralization enamel renal syndrome 1 3 3 06/29/22 20220624 NES 220624 Widely involved in cell signalling, either by direct signal transduction or acting as a second-messenger, calcium regulates a large range of physiological cell functions and processes including regulatory effects on many enzymes and proteins, muscle contraction, neuronal transmission and genesis, cellular motility and growth. PTH promotes the synthesis of 1,25(OH) 2 D in the kidney leading to the increase of intestinal calcium absorption and to a feedback loop inhibition of PTH secretion.
- Subjects
PATHOLOGICAL physiology; CALCIUM; EXTRACELLULAR matrix proteins; BONE cysts; PARATHYROID hormone-related protein; MINERALIZATION; TOOTH demineralization
- Publication
Frontiers in Endocrinology, 2022, Vol 13, p1
- ISSN
1664-2392
- Publication type
Article
- DOI
10.3389/fendo.2022.932019