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- Title
Long-term survival of patients with AIDS, Pneumocystis carinii pneumonia, and respiratory failure.
- Authors
Friedman, Y; Franklin, C; Freels, S; Weil, M H
- Abstract
<bold>Objective: </bold>--To evaluate the long-term survival of patients admitted to the medical intensive care unit, Cook County Hospital, Chicago, Ill, with Pneumocystis carinii pneumonia and acute respiratory failure.<bold>Design: </bold>--Cohort study over a 4-year period.<bold>Setting: </bold>--Municipal teaching hospital.<bold>Patients: </bold>--Seventy-three consecutive patients who had 75 episodes of P carinii pneumonia and acute respiratory failure were followed up from the time of hospital admission until their deaths or the termination of the study.<bold>Outcome Measures: </bold>--Duration of survival from the time of initial hospital admission with diagnoses of P carinii pneumonia and acute respiratory failure.<bold>Results: </bold>--Consistent with recent reports of improved short-term outcome, the immediate hospital survival was 47% (35/75). The 1-year survival was 37% (95% confidence interval, 26% to 49%). Two patients have survived for 40 months. Almost three quarters of the patients who survived hospitalization lived for at least 1 year.<bold>Conclusions: </bold>--The long-term prognosis for patients with the acquired immunodeficiency syndrome, P carinii pneumonia, and acute respiratory failure is now substantially better than anticipated. Respiratory failure due to P carinii pneumonia does not necessarily signify the terminal phase of human immunodeficiency virus infection. Accordingly, patients with the acquired immunodeficiency syndrome, P carinii pneumonia, and acute respiratory failure can be appropriate candidates for life support in medical intensive care units.
- Subjects
ILLINOIS; MORTALITY of AIDS patients; HOSPITAL care; LONGITUDINAL method; EVALUATION of medical care; PNEUMOCYSTIS pneumonia; PROGNOSIS; RESPIRATORY insufficiency
- Publication
JAMA: Journal of the American Medical Association, 1991, Vol 266, Issue 1, p89
- ISSN
0098-7484
- Publication type
journal article
- DOI
10.1001/jama.266.1.89