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- Title
Thrombophilic screening in patients with paroxysmal nocturnal haemoglobinuria: a pilot study.
- Authors
Dragoni, Francesco; Iori, Anna Paola; Pignoloni, Patrizia; Minotti, Chiara; Chiarotti, Flavia; Mazzucconi, Maria Gabriella; Mengarelli, Andrea; Arcese, William; Foà, Robin; Avvisati, Giuseppe
- Abstract
The article focuses on a study on patients with paroxysmal nocturnal hemoglobinuria (PNH) for thrombophilic screening. It discusses PNH which is an acquired clonal disorder of hematopoietic cells and mentions details of the study. The conclusion indicates that an immune-system involvement in patients with PNH could contribute to the development of antiphospholipid antibodies (APA), the presence of which can help in identifying patients with additional risk from thrombosis.
- Subjects
PAROXYSMAL hemoglobinuria; PHOSPHOLIPID antibodies; HEMOLYTIC anemia; HEMATOPOIETIC stem cell transplantation; THROMBOSIS
- Publication
British Journal of Haematology, 2010, Vol 150, Issue 4, p492
- ISSN
0007-1048
- Publication type
Letter
- DOI
10.1111/j.1365-2141.2010.08230.x