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Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease.
Published in:
JAMA Dermatology, 2015, v. 151, n. 8, p. 912, doi. 10.1001/jamaneurol.2015.1099
By:
- Quiroz, Yakeel T.;
- Schultz, Aaron P.;
- Chen, Kewei;
- Protas, Hillary D.;
- Brickhouse, Michael;
- Fleisher, Adam S.;
- Langbaum, Jessica B.;
- Thiyyagura, Pradeep;
- Fagan, Anne M.;
- Shah, Aarti R.;
- Muniz, Martha;
- Arboleda-Velasquez, Joseph F.;
- Munoz, Claudia;
- Garcia, Gloria;
- Acosta-Baena, Natalia;
- Giraldo, Margarita;
- Tirado, Victoria;
- Ramírez, Dora L.;
- Tariot, Pierre N.;
- Dickerson, Bradford C.
Publication type:
Article
Alzheimer's Prevention Initiative: A Plan to Accelerate the Evaluation of Presymptomatic Treatments.
Published in:
Journal of Alzheimer's Disease, 2011, v. 26, p. 321, doi. 10.3233/JAD-2011-0059
By:
- Ashford;
- Rosen;
- Adamson;
- Bayley;
- Sabri;
- Furst;
- Black;
- Weiner;
- Reiman, Eric M.;
- Tariot, Pierre N.;
- Langbaum, Jessica B.S.;
- Ayutyanont, Napatkamon;
- Fleisher, Adam S.;
- Chen, Kewei;
- Kosik, Kenneth S.;
- Lopera, Francisco;
- Caselli, Richard J.;
- Quiroz, Yakeel T.
Publication type:
Article
Alzheimer's Prevention Initiative: A Plan to Accelerate the Evaluation of Presymptomatic Treatments.
Published in:
Journal of Alzheimer's Disease, 2011, v. 26, p. 321
By:
- Ashford, J. Wesson;
- Rosen, Allyson;
- Adamson, Maheen;
- Bayley, Peter;
- Sabri, Osama;
- Furst, Ansgar;
- Black, Sandra E.;
- Weiner, Michael;
- Reiman, Eric M.;
- Langbaum, Jessica B.S.;
- Fleisher, Adam S.;
- Caselli, Richard J.;
- Chen, Kewei;
- Ayutyanont, Napatkamon;
- Quiroz, Yakeel T.;
- Kosik, Kenneth S.;
- Lopera, Francisco;
- Tariot, Pierre N.
Publication type:
Article
Alzheimer's Prevention Initiative: a plan to accelerate the evaluation of presymptomatic treatments.
Published in:
2011
By:
- Reiman, Eric M;
- Langbaum, Jessica B S;
- Fleisher, Adam S;
- Caselli, Richard J;
- Chen, Kewei;
- Ayutyanont, Napatkamon;
- Quiroz, Yakeel T;
- Kosik, Kenneth S;
- Lopera, Francisco;
- Tariot, Pierre N
Publication type:
journal article
Memantine for Patients With Alzheimer Disease—Reply.
Published in:
2004
By:
- Tariot, Pierre N.
Publication type:
Letter
Memantine Treatment in Patients With Moderate to Severe Alzheimer Disease Already Receiving Donepezil: A Randomized Controlled Trial.
Published in:
JAMA: Journal of the American Medical Association, 2004, v. 291, n. 3, p. 317, doi. 10.1001/jama.291.3.317
By:
- Tariot, Pierre N.;
- Farlow, Martin R.;
- Grossberg, George T.;
- Graham, Stephen M.;
- McDonald, Scott;
- Gergel, Ivan
Publication type:
Article
Treating Behavioral Problems in Patients With Alzheimer's Disease.
Published in:
Psychiatric Times, 2007, v. 24, p. 11
By:
- Tariot, Pierre N.
Publication type:
Article
BACE inhibition causes rapid, regional, and non-progressive volume reduction in Alzheimer's disease brain.
Published in:
2020
By:
- Sur, Cyrille;
- Kost, James;
- Scott, David;
- Adamczuk, Katarzyna;
- Fox, Nick C;
- Cummings, Jeffrey L;
- Tariot, Pierre N;
- Aisen, Paul S;
- Vellas, Bruno;
- Voss, Tiffini;
- Mahoney, Erin;
- Mukai, Yuki;
- Kennedy, Matthew E;
- Lines, Christopher;
- Michelson, David;
- Egan, Michael F
Publication type:
journal article
Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE): Alzheimer's Disease Trial.
Published in:
Schizophrenia Bulletin, 2003, v. 29, n. 1, p. 57, doi. 10.1093/oxfordjournals.schbul.a006991
By:
- Schneider, Lon S.;
- Ismail, M. Saleem;
- Dagerman, Karen;
- Davis, Sonia;
- Olin, Jason;
- McManus, Dennis;
- Pfeiffer, Eric;
- Ryan, J. Michael;
- Sultzer, David L.;
- Tariot, Pierre N.
Publication type:
Article
Effects of the active amyloid beta immunotherapy CAD106 on PET measurements of amyloid plaque deposition in cognitively unimpaired APOE ε4 homozygotes.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 3, p. 1839, doi. 10.1002/alz.13532
By:
- Riviere, Marie‐Emmanuelle;
- Langbaum, Jessica B.;
- Turner, R. Scott;
- Rinne, Juha O.;
- Sui, Yihan;
- Cazorla, Pilar;
- Ricart, Javier;
- Meneses, Kathleen;
- Caputo, Angelika;
- Tariot, Pierre N.;
- Reiman, Eric M.;
- Graf, Ana
Publication type:
Article
Informed consent process experience in Alzheimer's Prevention Initiative (API) Autosomal Dominant Alzheimer's Disease Colombia trial.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082483
By:
- Ríos‐Romenets, Silvia;
- Giraldo‐Chica, Margarita M.;
- Gutierrez, Madelyn;
- Acosta‐Baena, Natalia;
- Espinosa, Alejandro;
- Quiroz, Yakeel T.;
- Ruiz, Alejandra;
- Giraldo, Andrea;
- Langbaum, Jessica B.;
- Cho, William;
- Reiman, Eric M.;
- Tariot, Pierre N.;
- Lopera, Francisco
Publication type:
Article
Contraception in Female Volunteer in Alzheimer's Prevention Initiative Autosomal‐dominant Alzheimer's disease Colombia Trial, a Phase II Clinical Trial to Test Safety and Efficacy of Crenezumab.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082348
By:
- Martínez, Juan F;
- Bustamante, Christian;
- Navarro, Alexander;
- Lopera, Margarita M;
- Villegas, Gustavo;
- Acosta‐Baena, Natalia;
- Duque, Sindy;
- Tariot, Pierre N.;
- Langbaum, Jessica B.;
- Ríos‐Romenets, Silvia;
- Lopera, Francisco
Publication type:
Article
Effect of Age Range on Power for a Clinical Trial Investigating the Effect of Intensive Systolic Blood Pressure Control on White Matter Hyperintensity Volume Accumulation.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.080216
By:
- Pruzin, Jeremy J.;
- Chen, Yinghua;
- Chen, Kewei;
- Koijs, Daniel;
- Newby, Danielle;
- Winchester, Laura M;
- Thomas, Ronald G.;
- McGrath, Emer R;
- Su, Yi;
- Reboussin, David M.;
- Pajewski, Nicholas M.;
- Beiser, Alexa S.;
- Seshadri, Sudha;
- Tariot, Pierre N.
Publication type:
Article
Statistical innovations in the API ADAD Colombia trial: a randomized, double‐blind, placebo‐controlled, parallel‐group study in cognitively unimpaired PSEN1 E280A mutation carriers evaluating efficacy and safety of crenezumab.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.070863
By:
- Hu, Nan;
- Mackey, Howard;
- Doody, Rachelle S.;
- Lopera, Francisco;
- Tariot, Pierre N.;
- Reiman, Eric M.;
- Thomas, Ronald G.;
- Langbaum, Jessica B.;
- Sink, Kaycee M.
Publication type:
Article
Effect of Age Range on Power for a Clinical Trial Investigating the Effect of Intensive Systolic Blood Pressure Control on White Matter Hyperintensity Volume Accumulation.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081985
By:
- Pruzin, Jeremy J.;
- Chen, Yinghua;
- Chen, Kewei;
- Koijs, Daniel;
- Newby, Danielle;
- Winchester, Laura M;
- Thomas, Ronald G.;
- McGrath, Emer R;
- Su, Yi;
- Reboussin, David M.;
- Pajewski, Nicholas M.;
- Beiser, Alexa S.;
- Seshadri, Sudha;
- Tariot, Pierre N.
Publication type:
Article
IC‐P‐010: COMPARING CEREBRAL WHITE MATTER, CEREBELLAR, AND PONTINE REFERENCE REGIONS TO CHARACTERIZE FLORBETAPIR PET MEASUREMENTS OF AMYLOID‐β BURDEN IN PSEN1 E280A MUTATION CARRIERS AND NONCARRIERS FROM THE COLOMBIAN AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE KINDRED
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 14, p. P20, doi. 10.1016/j.jalz.2018.06.2074
By:
- Ghisays, Valentina;
- Protas, Hillary;
- Chen, Yinghua;
- DeMarco, Eric L.;
- Tariot, Pierre N.;
- Langbaum, Jessica B.;
- Quiroz, Yakeel T.;
- Lopera, Francisco;
- Reiman, Eric M.;
- Chen, Kewei
Publication type:
Article
Longitudinal lumbar puncture adherence in the Alzheimer's Prevention Initiative Autosomal‐Dominant Alzheimer's Disease Colombia Trial.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.065233
By:
- Acosta‐Baena, Natalia;
- Ríos‐Romenets, Silvia;
- Giraldo‐Chica, Margarita;
- Espinosa, Alejandro;
- Ramos, Claudia;
- Aguillon, David;
- Aponte, Claudia;
- Leon‐Varela, Yudy M;
- Piedrahita, Francisco;
- Lopez, Liliana;
- Gomez, Francisco;
- Ehrhard, Patricia;
- Sink, Kaycee M.;
- Tariot, Pierre N.;
- Reiman, Eric M.;
- Lopera, Francisco
Publication type:
Article
Electrocardiogram differences in cognitively unimpaired PSEN1‐E280A carriers and non‐carriers from the Alzheimer's Prevention Initiative Autosomal‐Dominant Alzheimer's Disease Colombia Trial.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.064023
By:
- Vasquez, Daniel;
- Giraldo‐Chica, Margarita;
- Malek‐Ahmadi, Michael H.;
- Jaramillo, Carlos J;
- Acosta‐Baena, Natalia;
- Espinosa, Alejandro;
- Ramos, Claudia;
- Aguillon, David;
- Aponte, Claudia;
- Londoño, Jennifer;
- Hu, Nan;
- Su, Yi;
- Ehrhard, Patricia;
- Sink, Kaycee M.;
- Tariot, Pierre N.;
- Reiman, Eric M.;
- Ríos‐Romenets, Silvia;
- Lopera, Francisco
Publication type:
Article
API ADAD Colombia Trial initial findings: a randomized, double‐blind, placebo‐controlled, parallel‐ group study in cognitively unimpaired PSEN1 E280A mutation carriers evaluating efficacy and safety of crenezumab.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.069724
By:
- Sink, Kaycee M.;
- Doody, Rachelle S.;
- Ríos‐Romenets, Silvia;
- Tariot, Pierre N.;
- Reiman, Eric M.;
- Langbaum, Jessica B.
Publication type:
Article
Bioequivalence and safety comparison of once‐weekly donepezil transdermal system with oral donepezil: results of a phase 1 pharmacokinetic study in healthy volunteers.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.068981
By:
- Tariot, Pierre N.;
- Braeckman, Rene;
- Oh, Charles
Publication type:
Article
Efficacy and safety of pimavanserin in patients with Alzheimer's dementia psychosis in the HARMONY phase 3, randomized discontinuation study: a post hoc subgroup analysis.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.062364
By:
- Cummings, Jeffrey;
- Devanand, Davangere P;
- Ballard, Clive G;
- Tariot, Pierre N.;
- Hendrix, Suzanne B.;
- Dickson, Samuel P.;
- Li, Caiyan;
- Abler, Victor;
- Pathak, Sanjeev;
- Stankovic, Srdjan
Publication type:
Article
Clinical Profiles of Persons Who Progress to Cognitive Impairment in the Alzheimer's Prevention Initiative (API) ADAD Colombia Trial.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.069107
By:
- Giraldo‐Chica, Margarita;
- Acosta‐Baena, Natalia;
- Espinosa, Alejandro;
- Ramos, Claudia;
- Langbaum, Jessica B.;
- Sink, Kaycee M.;
- Tariot, Pierre N.;
- Reiman, Eric M.;
- Lopera, Francisco;
- Ríos‐Romenets, Silvia
Publication type:
Article
Reproductive health data and its relationship to baseline brain imaging and cognitive measurements in cognitively unimpaired female PSEN1 E280A mutation carriers and non‐carriers from the API ADAD Trial.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.062000
By:
- Ghisays, Valentina;
- Vila‐Castelar, Clara;
- Giraldo‐Chica, Margarita;
- Acosta‐Baena, Natalia;
- Protas, Hillary D.;
- Malek‐Ahmadi, Michael H.;
- Chen, Yinghua;
- Luo, Ji;
- Lee, Wendy;
- Bocanegra, Yamile;
- Muñoz, Claudia;
- Herrera, Karina;
- Hu, Nan;
- Sink, Kaycee M.;
- Clayton, David;
- Alvarez, Sergio;
- Langbaum, Jessica B.;
- Chen, Kewei;
- Su, Yi;
- Tariot, Pierre N.
Publication type:
Article
Testing the amyloid cascade hypothesis: Prevention trials in autosomal dominant Alzheimer disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 12, p. 2687, doi. 10.1002/alz.12624
By:
- Levin, Johannes;
- Vöglein, Jonathan;
- Quiroz, Yakeel T.;
- Bateman, Randall J.;
- Ghisays, Valentina;
- Lopera, Francisco;
- McDade, Eric;
- Reiman, Eric;
- Tariot, Pierre N.;
- Morris, John C.
Publication type:
Article
Sex differences in cognitive resilience in preclinical autosomal‐dominant Alzheimer's disease carriers and non‐carriers: Baseline findings from the API ADAD Colombia Trial.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 11, p. 2272, doi. 10.1002/alz.12552
By:
- Vila‐Castelar, Clara;
- Tariot, Pierre N.;
- Sink, Kaycee M.;
- Clayton, David;
- Langbaum, Jessica B.;
- Thomas, Ronald G.;
- Chen, Yinghua;
- Su, Yi;
- Chen, Kewei;
- Hu, Nan;
- Giraldo‐Chica, Margarita;
- Tobón, Carlos;
- Acosta‐Baena, Natalia;
- Luna, Ernesto;
- Londoño, Marisol;
- Ospina, Paula;
- Tirado, Victoria;
- Muñoz, Claudia;
- Henao, Eliana;
- Bocanegra, Yamile
Publication type:
Article
Psychological status in the participants of the API ADAD Colombia trial assisted by a comprehensive mental health program during COVID 19 pandemic.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.057396
By:
- Ramos, Claudia;
- Madrigal, Claudia;
- Giraldo‐Chica, Margarita;
- Acosta‐Baena, Natalia;
- Aponte, Claudia;
- Aguillon, David;
- Gómez, Manuela;
- Espinosa, Alejandro;
- Madrigal, Lucia;
- Uribe, Claramonika;
- Saldarriaga, Amanda;
- Alzate, Diana;
- Ruiz, Alejandra;
- Andrade‐Villegas, Angela M;
- Lopez, Hugo Elias;
- Langbaum, Jessica B;
- Sink, Kaycee M;
- Reiman, Eric M;
- Tariot, Pierre N;
- Rios‐Romenets, Silvia
Publication type:
Article
API generation program: Active immunotherapy CAD106 slows amyloid deposition in cognitively unimpaired APOE4 homozygotes.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.051287
By:
- Riviere, Marie‐Emmanuelle;
- Turner, Raymond Scott;
- Sui, Yihan;
- Laurent, Nathalie;
- Langbaum, Jessica B.;
- Cazorla, Pilar;
- Ricart, Javier;
- Seneca, Nicholas;
- Caputo, Angelika;
- Reiman, Eric M.;
- Tariot, Pierre N.;
- Graf, Ana
Publication type:
Article
Sex differences in blood‐based biomarkers in individuals with autosomal dominant Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.055011
By:
- Vila‐Castelar, Clara;
- Lopera, Francisco;
- Zetterberg, Henrik;
- Hansson, Oskar;
- Dage, Jeffrey L;
- Janelidze, Shorena;
- Chen, Yinghua;
- Su, Yi;
- Garcia, Gloria;
- Aguillon, David;
- Baena, Ana Y.;
- Giraldo‐Chica, Margarita;
- Protas, Hillary D.;
- Ghisays, Valentina;
- Rios‐Romenets, Silvia;
- Tariot, Pierre N.;
- Blennow, Kaj;
- Reiman, Eric M.;
- Quiroz, Yakeel T.
Publication type:
Article
Depression and anxiety disorder along life in familial Alzheimer's disease in the API ADAD Colombia trial: Neuropsychiatry and behavioral neurology/Assessment/Measurement of neuropsychiatric/Behavioral and psychological symptoms.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 6, p. 1, doi. 10.1002/alz.041314
By:
- Ramos, Claudia;
- Rios‐Romenets, Silvia;
- Giraldo‐Chica, Margarita;
- Acosta‐Baena, Natalia;
- Tobon, Carlos;
- Lopez, Hugo;
- Aguirre‐Acevedo, Daniel C.;
- Langbaum, Jessica B.;
- Reiman, Eric M.;
- Tariot, Pierre N.;
- Lopera, Francisco
Publication type:
Article
Screening characteristics of PSEN1 E280A mutation carriers and non‐carriers in the API Autosomal Dominant Alzheimer's Disease Colombia Trial: Neuropsychiatry and behavioral neurology/presymptomatic disease/prodromal disease/prodromal states.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 6, p. 1, doi. 10.1002/alz.040336
By:
- Rios‐Romenets, Silvia;
- Giraldo‐Chica, Margarita;
- Acosta‐Baena, Natalia;
- Tobon, Carlos;
- Ramos P, Claudia;
- Lopez, Hugo;
- Aguirre‐Acevedo, Daniel C.;
- Muñoz, Claudia;
- Bocanegra, Yamile;
- Henao, Eliana;
- Tirado, Victoria;
- Ospina, Paula;
- Sink, Kaycee M.;
- Hu, Nan;
- Langbaum, Jessica B.;
- Reiman, Eric M.;
- Tariot, Pierre N.;
- Lopera, Francisco
Publication type:
Article
The Alzheimer's Prevention Registry: Accelerating recruitment and enrollment into Alzheimer's‐focused studies: Epidemiology / Innovative methods in epidemiology (i.e., assessment methods, design, recruitment strategies, statistical methods, etc.).
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043931
By:
- High, Nellie M;
- Kettenhoven, Cassandra L;
- Graf, Hayley;
- Reiman, Eric M;
- Tariot, Pierre N;
- Langbaum, Jessica B
Publication type:
Article
The Alzheimer's Prevention Registry: Success metrics and lessons learned in registry member retention through online engagement campaigns: Epidemiology / Innovative methods in epidemiology (i.e., assessment methods, design, recruitment strategies, statistical methods, etc.)
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043531
By:
- Kettenhoven, Cassandra L;
- High, Nellie M;
- Salata, Hayley;
- Reiman, Eric M;
- Tariot, Pierre N;
- Langbaum, Jessica B
Publication type:
Article
Success of referring participants to the Generation program and lessons learned for future enrollment into Alzheimer's disease prevention trials: Human: Improving clinical trial methodology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043112
By:
- Gordon, David;
- Salata, Hayley;
- Walsh, Trisha L.;
- High, Nellie M.;
- Kettenhoven, Cassandra L.;
- Reiman, Eric M.;
- Tariot, Pierre N.;
- Langbaum, Jessica B.
Publication type:
Article
Depression and anxiety disorder along life in familial Alzheimer's disease in the API ADAD Colombia trial: Neuropsychiatry and behavioral neurology/Assessment/Measurement of neuropsychiatric/Behavioral and psychological symptoms.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041314
By:
- Ramos, Claudia;
- Rios‐Romenets, Silvia;
- Giraldo‐Chica, Margarita;
- Acosta‐Baena, Natalia;
- Tobon, Carlos;
- Lopez, Hugo;
- Aguirre‐Acevedo, Daniel C.;
- Langbaum, Jessica B.;
- Reiman, Eric M.;
- Tariot, Pierre N.;
- Lopera, Francisco
Publication type:
Article
Sex differences in neurodegeneration and memory performance in preclinical autosomal dominant Alzheimer's disease: Baseline findings from the API ADAD trial: Intersections of sex/gender and race/ethnicity in cognitive aging and Alzheimer's disease trajectories
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041225
By:
- Vila‐Castelar, Clara;
- Tariot, Pierre N;
- Sink, Kaycee M;
- Clayton, David;
- Langbaum, Jessica B;
- Thomas, Ronald G;
- Chen, Yinghua;
- Su, Yi;
- Hu, Nan;
- Giraldo‐Chica, Margarita;
- Tobon, Carlos;
- Acosta‐Baena, Natalia;
- Luna‐Maldonado, Ernesto;
- Londoño, Marisol;
- Ospina, Paula;
- Tirado, Victoria;
- Muñoz, Claudia;
- Henao, Eliana;
- Bocanegra, Yamile;
- Alvarez, Sergio
Publication type:
Article
The API Generation program: Umibecestat treatment and discontinuation effects on hippocampal and whole brain volumes in the overall population and amyloid‐negative APOE4 homozygotes: Alzheimer's Prevention Initiative (API) Generation program: Baseline characteristics and umibecestat results during treatment and follow‐up
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041142
By:
- Reiman, Eric M.;
- Tariot, Pierre N.;
- Borowsky, Beth;
- Liu, Fonda;
- Riviere, Marie‐Emmanuelle;
- Rouzade‐Dominguez, Marie‐Laure;
- Cazorla, Pilar;
- Quinn, Matt;
- Ricart, Javier;
- Langbaum, Jessica B.;
- Viglietta, Vissia;
- Sui, Yihan;
- Caputo, Angelika;
- Graf, Ana;
- Seneca, Nicholas;
- Neumann, Ulf;
- Eichenlaub, Udo;
- Chien, Yuchen;
- Arkuszewski, Michal;
- Piccard, Hernan
Publication type:
Article
Umibecestat in the API Generation program: Worsening in RBANS and/or CDR on treatment reverses after wash‐out: Alzheimer's Prevention Initiative (API) Generation program: Baseline characteristics and umibecestat results during treatment and follow‐up
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041140
By:
- Graf, Ana;
- Riviere, Marie‐Emmanuelle;
- Liu, Fonda;
- Rouzade‐Dominguez, Marie‐Laure;
- Cazorla, Pilar;
- Quinn, Matt;
- Arkuszewski, Michal;
- Ricart, Javier;
- Langbaum, Jessica B.;
- Piccard, Hernan;
- Sui, Yihan;
- Quarg, Peter;
- Caputo, Angelika;
- Reiman, Eric M.;
- Tariot, Pierre N.
Publication type:
Article
The Generation program: Baseline characteristics of cognitively unimpaired APOE4 carriers recruited for Generation study 1 and Generation study 2: Alzheimer's Prevention Initiative (API) Generation program: Baseline characteristics and umibecestat results during treatment and follow‐up
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041139
By:
- Tariot, Pierre N.;
- Borowsky, Beth;
- Liu, Fonda;
- Riviere, Marie‐Emmanuelle;
- Rouzade‐Dominguez, Marie‐Laure;
- Cazorla, Pilar;
- Quinn, Matt;
- Ricart, Javier;
- Langbaum, Jessica B.;
- Viglietta, Vissia;
- Sui, Yihan;
- Caputo, Angelika;
- Reiman, Eric M.;
- Graf, Ana
Publication type:
Article
Screening characteristics of PSEN1 E280A mutation carriers and non‐carriers in the API Autosomal Dominant Alzheimer's Disease Colombia Trial: Neuropsychiatry and behavioral neurology/presymptomatic disease/prodromal disease/prodromal states.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040336
By:
- Rios‐Romenets, Silvia;
- Giraldo‐Chica, Margarita;
- Acosta‐Baena, Natalia;
- Tobon, Carlos;
- Ramos P, Claudia;
- Lopez, Hugo;
- Aguirre‐Acevedo, Daniel C.;
- Muñoz, Claudia;
- Bocanegra, Yamile;
- Henao, Eliana;
- Tirado, Victoria;
- Ospina, Paula;
- Sink, Kaycee M.;
- Hu, Nan;
- Langbaum, Jessica B.;
- Reiman, Eric M.;
- Tariot, Pierre N.;
- Lopera, Francisco
Publication type:
Article
The Alzheimer's prevention initiative Generation program: A global perspective on best practices for site support and engagement to accelerate participant recruitment: Clinical trial design and implementation.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.039186
By:
- Walsh, Trisha L.;
- Riviere, Marie‐Emmanuelle;
- Tariot, Pierre N.;
- Alred, Melody;
- Doak, Karen;
- Liu, Fonda;
- Ricart, Javier;
- Scholten, Ingo;
- Arbuckle, Julian;
- Quinn, Matt;
- Duff, Laurie;
- Smith, Molly;
- Graf, Ana;
- Langbaum, Jessica B.
Publication type:
Article
Cognitive outcomes in trials of two BACE inhibitors in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1483, doi. 10.1002/alz.12164
By:
- Wessels, Alette M.;
- Lines, Christopher;
- Stern, Robert A.;
- Kost, James;
- Voss, Tiffini;
- Mozley, Lyn Harper;
- Furtek, Christine;
- Mukai, Yuki;
- Aisen, Paul S.;
- Cummings, Jeffrey L.;
- Tariot, Pierre N.;
- Vellas, Bruno;
- Dupre, Nicole;
- Randolph, Christopher;
- Michelson, David;
- Andersen, Scott W.;
- Shering, Craig;
- Sims, John R.;
- Egan, Michael F.
Publication type:
Article
Brain imaging measurements of fibrillar amyloid‐β burden, paired helical filament tau burden, and atrophy in cognitively unimpaired persons with two, one, and no copies of the APOE ε4 allele.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 4, p. 598, doi. 10.1016/j.jalz.2019.08.195
By:
- Ghisays, Valentina;
- Goradia, Dhruman D.;
- Protas, Hillary;
- Bauer, Robert J.;
- Devadas, Vivek;
- Tariot, Pierre N.;
- Lowe, Val J.;
- Knopman, David S.;
- Petersen, Ronald C.;
- Jack, Clifford R.;
- Caselli, Richard J.;
- Su, Yi;
- Chen, Kewei;
- Reiman, Eric M.
Publication type:
Article
F4‐04‐04: ASSOCIATION BETWEEN CEREBRAL AMYLOIDOSIS AND WORSE COGNITIVE PERFORMANCE IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE: BASELINE FINDINGS FROM THE API COLOMBIA AUTOSOMAL DOMINANT AD TRIAL.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1224, doi. 10.1016/j.jalz.2019.06.4728
By:
- Quiroz, Yakeel T.;
- Tariot, Pierre N.;
- Sink, Kaycee;
- Clayton, David;
- Langbaum, Jessica B.;
- Thomas, Ronald G.;
- Giraldo, Margarita;
- Tobon, Carlos;
- Acosta-Baena, Natalia;
- Luna, Ernesto;
- Londono, Marisol;
- Ospina, Paula;
- Tirado, Victoria;
- Alvarez, Sergio;
- Chen, Kewei;
- Su, Yi;
- Goradia, Dhruman D.;
- Thiyyagura, Pradeep;
- VanGilder, Paul S.;
- Luo, Ji
Publication type:
Article
F4‐04‐03: RELATIONSHIPS BETWEEN BASELINE BRAIN IMAGING BIOMARKER MEASUREMENTS AND AGE IN THE API AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE COLOMBIA TRIAL.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1223, doi. 10.1016/j.jalz.2019.06.4727
By:
- Su, Yi;
- Rios-Romenets, Silvia;
- Tariot, Pierre N.;
- Sink, Kaycee;
- Clayton, David;
- Hu, Nan;
- Guthrie, Heather;
- Smith, Jillian;
- Cho, William;
- Langbaum, Jessica B.;
- Thomas, Ronald G.;
- Giraldo, Margarita;
- Tobon, Carlos;
- Acosta-Baena, Natalia;
- Navarro, Alexander;
- Piedrahita, Francisco;
- Alvarez, Sergio;
- Chen, Kewei;
- Goradia, Dhruman D.;
- Thiyyagura, Pradeep
Publication type:
Article
F4‐04‐01: TRIAL DESIGN, DATA SHARING RISK MITIGATION, AND BASELINE CLINICAL AND COGNITIVE DATA FROM THE API AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE COLOMBIA TRIAL.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1222, doi. 10.1016/j.jalz.2019.06.4725
By:
- Tariot, Pierre N.;
- Lopera, Francisco;
- Sink, Kaycee;
- Hu, Nan;
- Guthrie, Heather;
- Smith, Jillian;
- Cho, William;
- Langbaum, Jessica B.;
- Thomas, Ronald G.;
- Giraldo, Margarita;
- Tobon, Carlos;
- Acosta-Baena, Natalia;
- Munoz, Claudia;
- Ospina, Paula;
- Torado, Victoria;
- Henao, Eliana;
- Bocanegra, Yamile;
- Chen, Kewei;
- Su, Yi;
- Goradia, Dhruman D.
Publication type:
Article
O3‐10‐02: VERUBECESTAT‐INDUCED BRAIN VOLUME LOSS OCCURS RAPIDLY AND ONLY IN AMYLOID‐ENRICHED BRAIN REGIONS IN EPOCH, A PHASE 3 TRIAL IN MILD‐TO‐MODERATE ALZHEIMER'S DISEASE PATIENTS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P909, doi. 10.1016/j.jalz.2019.06.4679
By:
- Sur, Cyrille;
- Kost, James;
- Scott, David;
- Adamczuk, Katarzyna;
- Fox, Nick C.;
- Cummings, Jeffrey L.;
- Tariot, Pierre N.;
- Aisen, Paul S.;
- Vellas, Bruno;
- Voss, Tiffini;
- Mukai, Yuki;
- Michelson, David;
- Egan, Michael F.
Publication type:
Article
P3‐033: GENEMATCH: A NOVEL RECRUITMENT REGISTRY OF APOE CHARACTERIZED ADULTS TO ACCELERATE RECRUITMENT AND ENROLLMENT INTO ALZHEIMER'S PREVENTION STUDIES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P938, doi. 10.1016/j.jalz.2019.06.3059
By:
- Gordon, David;
- Graf, Hayley;
- Walsh, Trisha;
- High, Nellie M.;
- Reiman, Eric M.;
- Tariot, Pierre N.;
- Langbaum, Jessica B.
Publication type:
Article
O3‐02‐02: AMYLOID PET, TAU PET, AND MRI MEASUREMENTS IN COGNITIVELY UNIMPAIRED PERSONS WITH TWO, ONE, AND NO COPIES OF THE APOE4 ALLELE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P878, doi. 10.1016/j.jalz.2019.06.4631
By:
- Ghisays, Valentina;
- Goradia, Dhruman D.;
- Protas, Hillary;
- Bauer, Robert;
- Devadas, Vivek;
- Tariot, Pierre N.;
- Lowe, Val J.;
- Knopman, David S.;
- Petersen, Ronald C.;
- Jack, Clifford R.;
- Caselli, Richard J.;
- Su, Yi;
- Chen, Kewei;
- Reiman, Eric M.
Publication type:
Article
FTS3‐01‐05: FURTHER ANALYSES OF COGNITIVE OUTCOMES IN THE APECS PHASE‐3 TRIAL OF VERUBECESTAT IN PRODROMAL AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P874, doi. 10.1016/j.jalz.2019.06.4622
By:
- Egan, Michael F.;
- Kost, James;
- Lines, Christopher;
- Voss, Tiffini;
- Mozley, Lyn Harper;
- Furtek, Christine;
- Mukai, Yuki;
- Aisen, Paul S.;
- Cummings, Jeffrey L.;
- Tariot, Pierre N.;
- Vellas, Bruno;
- Dupre, Nicole;
- Randolph, Christopher;
- Sur, Cyrille;
- Michelson, David
Publication type:
Article
FTS3‐01‐02: SUBGROUP POPULATIONS IN AMARANTH, A RANDOMIZED PHASE 2/3 STUDY IN EARLY ALZHEIMER'S DISEASE WITH LANABECESTAT.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P872, doi. 10.1016/j.jalz.2019.06.4619
By:
- Tariot, Pierre N.;
- Selzler, Katherine J.;
- Wessels, Alette M.;
- Andersen, Scott W.;
- Mullen, Jamie;
- Zimmer, Jennifer A.;
- Sims, John R.
Publication type:
Article

Found: 142