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- Title
What's growing on? The growing teratoma syndrome.
- Authors
Denaro, Luca; Pluchinotta, Francesca; Faggin, Roberto; Manara, Renzo; Calderone, Milena; Viscardi, Elisabetta; Gardiman, Marina; Rossetto, Marta; Perilongo, Giorgio; d'Avella, Domenico
- Abstract
Background: The growing teratoma syndrome (GTS) consists of a mature teratoma paradoxically enlarging during or after chemotherapy for malignant nongerminomatous germ cell tumors. Methods and results: We report two cases of GTS occurring in association with NSGCT of the pineal gland. Although an unusual event, clinicians and radiologists should be aware of its natural history. Conclusions: When normalized tumor markers after chemotherapy are associated with imaging features of a growing mass, the hypothesis of GTS must be taken in consideration. When early diagnosed, GTS can be managed surgically with good results.
- Subjects
TERATOMA; GERM cell tumors; CANCER treatment; PINEAL gland; DRUG therapy
- Publication
Acta Neurochirurgica, 2010, Vol 152, Issue 11, p1943
- ISSN
0001-6268
- Publication type
Article
- DOI
10.1007/s00701-010-0807-2