We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
TissueEnrich: Tissue-specific gene enrichment analysis.
- Authors
Jain, Ashish; Tuteja, Geetu
- Abstract
Summary RNA-Seq data analysis results in lists of genes that may have a similar function, based on differential gene expression analysis or co-expression network analysis. While tools have been developed to identify biological processes that are enriched in the genes sets, there remains a need for tools that identify enrichment of tissue-specific genes. Therefore, we developed TissueEnrich, a tool that calculates tissue-specific gene enrichment in an input gene set. We demonstrated that TissueEnrich can assign tissue identities to single cell clusters and differentiated embryonic stem cells. Availability and implementation The TissueEnrich web application is freely available at http://tissueenrich.gdcb.iastate.edu/. The R package is available through Bioconductor at https://bioconductor.org/packages/TissueEnrich. Both the web application and R package are for non-profit academic use under the MIT license. Supplementary information Supplementary data are available at Bioinformatics online.
- Subjects
EMBRYONIC stem cells; GENE regulatory networks; WEB-based user interfaces; GENES; GENE expression
- Publication
Bioinformatics, 2019, Vol 35, Issue 11, p1966
- ISSN
1367-4803
- Publication type
Article
- DOI
10.1093/bioinformatics/bty890