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- Title
Successful Treatment of a 19-Month-Old Boy with Hepatitis Associated Aplastic Anemia by Infusion of Umbilical Cord-Derived Mesenchymal Stromal Cells: A Case Report.
- Authors
Fang, Liu; Meikuang, Lim; Ye, Guo; Xiaojuan, Chen; Wenyu, Yang; Min, Ruan; Lixian, Chang; Weiqiang, Wang; Zhibo, Han; Zhongchao, Han; Xiaofan, Zhu
- Abstract
Here we presented a case of a 19-month-old boy who developed severe aplastic anemia postacute hepatitis. He was treated successfully with the umbilical cord-derived mesenchymal stromal cells (UC-MSCs) infusion and cyclosporine A (CsA). The boy achieved both hematopoietic recovery and normal lymphocyte proportion. So far, his condition still remains stable. To our knowledge, there is a rare previous report on the utility of MSCs infusion for the treatment of hepatitis-associated aplastic anemia (HAAA). Considering the efficacy, safety, and strong operability, particularly for pediatric patient, the infusion of UC-MSCs combined with CsA could be an effective alternative for the treatment of HAAA.
- Subjects
HEPATITIS treatment; UMBILICAL cord; APLASTIC anemia; MESENCHYMAL stem cells; CYCLOSPORINE; CHILD patients
- Publication
Cell Transplantation, 2021, Vol 30, p1
- ISSN
0963-6897
- Publication type
Case Study
- DOI
10.1177/0963689720977144