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- Title
Pelvic lymphadenectomy in prostate cancer.
- Authors
Breyer, B. N.; Greene, K. L.; Dall'Era, M. A.; Davies, B. J.; Kane, C. J.
- Abstract
This review analyzes the anatomy of the prostate gland's lymphatic drainage, the optimal anatomic extend of pelvic lymph node dissection (PLND) and which dissection may be superior, who should undergo a PLND during prostatectomy, and its potential therapeutic benefits and complications. The prostate gland's lymphatic drainage can be variable, but frequently metastatic disease is found in the internal iliac chain. We conclude that the extended PLND yields the most lymph nodes and therefore may be superior. Some have demonstrated an unproven survival benefit after performing an extended PLND, possibly from removal of occult disease or from more accurate staging.Prostate Cancer and Prostatic Diseases (2008) 11, 320–324; doi:10.1038/pcan.2008.29; published online 20 May 2008
- Subjects
LYMPH nodes; PROSTATE cancer; EXOCRINE glands; SURGICAL drainage; RETROPUBIC prostatectomy
- Publication
Prostate Cancer & Prostatic Diseases, 2008, Vol 11, Issue 4, p320
- ISSN
1365-7852
- Publication type
Article
- DOI
10.1038/pcan.2008.29