We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Association between Neck Circumference and the Occurrence of Cardiovascular Events in Type 2 Diabetes: Beijing Community Diabetes Study 20 (BCDS-20).
- Authors
Yang, Guang-Ran; Yuan, Ming-Xia; Wan, Gang; Zhang, Xue-Lian; Fu, Han-Jing; Yuan, Shen-Yuan; Zhu, Liang-Xiang; Xie, Rong-Rong; Zhang, Jian-Dong; Li, Yu-Ling; Sun, Yan-Hua; Dai, Qin-Fang; Gao, Da-Yong; Cui, Xue-Li; Gao, Jian-Qin; Wang, Zi-Ming; Chen, Ying-Jun; Hu, Dong-Ming; Gao, Juan; Bai, Liyong
- Abstract
Background. Neck circumference (NC) was found to be related to the risk factors of cardiovascular disease. However, the effects of NC on cardiovascular disease are still controversial. A prospective study of Chinese patients with type 2 diabetes was performed to evaluate the relationship between NC and cardiovascular disease. Methods. A multicenter prospective study with eight-year follow-up was conducted in Beijing communities. Cardiovascular events were defined as myocardial infarction, unstable angina pectoris, hospitalization for heart failure, coronary revascularization, cardiac death, stroke, transient ischemic attack, and cerebral hemorrhage. Results. A total of 3,009 diabetic patients were recruited. Following an eight-year follow-up, 211 patients with cardiovascular events (105 in men and 106 in women) were identified. All patients were categorized into two groups according to the upper quartile of NC (43 cm in men and 39 cm in women). The prevalence of cardiovascular events in men with an NC >43 cm (16.48%) was higher than that in the group with an NC <43 cm (8.16%, p=0.007). The prevalence of cardiovascular events in women with the NC >39 cm (10.67%) was higher compared to the group with NC <39 cm (5.31%, p=0.004). The longitudinal prevalence of cardiovascular events in groups with different NC increased with the increasing duration of follow-up (p<0.001). Cox regression analysis showed that higher NC was associated with the occurrence of cardiovascular events after adjusting for confounding variables (adjusted HR = 2.305 (1.535–3.460)). Conclusions. NC was associated with the occurrence of cardiovascular events in type 2 diabetes in Chinese communities, and greater NC may increase the risk of cardiovascular events by about 2.3-fold.
- Subjects
CHINA; ANTHROPOMETRY; CARDIOVASCULAR diseases; CARDIOVASCULAR diseases risk factors; COMPARATIVE studies; LONGITUDINAL method; MEDICAL cooperation; NECK; TYPE 2 diabetes; REGRESSION analysis; RESEARCH; DISEASE prevalence; PROPORTIONAL hazards models; DESCRIPTIVE statistics
- Publication
BioMed Research International, 2019, p1
- ISSN
2314-6133
- Publication type
Article
- DOI
10.1155/2019/4242304