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- Title
Application of short tandem repeat of genomic DNA and mitochondrial DNA for identification of mixed-up tissue specimens.
- Authors
Sano, Kenji; Takayanagi, Kayoko; Kaneko, Taimei; Liu, Chunyan; Kinoshita, Tomoyuki; Nakamura, Naoshi; Asamura, Hideki; Ito, Makoto; Fukushima, Hirofumi; Hotchi, Masao
- Abstract
Deoxyribonucleic acid (DNA) typing methods, short tandem repeat of genomic DNA and mitochondrial DNA with the use of polymerase chain reaction amplification, were applied to formalin-fixed, paraffin-embedded tissues submitted for diagnosis, to identify and sort out mixed-up tissue specimens. These techniques were found to be reliable, reproducible and specific for personal identification, and thus to eliminate the need for further examinations and to prevent unnecessary surgery.
- Subjects
TISSUE analysis; GENOMES; MITOCHONDRIAL DNA
- Publication
Pathology International, 2000, Vol 50, Issue 1, p1
- ISSN
1320-5463
- Publication type
Article
- DOI
10.1046/j.1440-1827.2000.01010.x