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- Title
Initial outcomes with image‐guided partial breast irradiation delivered with intensity‐modulated radiation therapy.
- Authors
Shah, Chirag; Obi, Elizabeth; Tom, Martin C.; Manyam, Bindu V.; Obi, Betty; Al‐Hilli, Zahraa; Grobmyer, Stephen; Abraham, Jame; Xia, Ping; Murray, Eric; Cherian, Sheen; Tendulkar, Rahul D.
- Abstract
Patients were treated at a single institution to a dose of 30 Gy in five fractions delivered every other day using image‐guided intensity modulated radiation therapy (IMRT) partial breast irradiation. A total of 34 patients were treated with a median follow‐up of 4.6 months. The rate of acute Grade 1 dermatitis was 23.5% (n = 8), and Grade 1 fatigue was 17.6% (n = 6), with no Grade 2 or higher acute toxicities. The rate of chronic Grade 1 dermatitis was 25.0% (n = 6), Grade 1 fat necrosis 4.2% (n=1), with no patients demonstrating other chronic toxicities. Image‐guided APBI delivered with IMRT is associated with low rates of acute and chronic toxicity though additional follow‐up is warranted.
- Subjects
ADIPOSE tissues; BREAST tumors; FATIGUE (Physiology); NECROSIS; PATIENT safety; RADIATION doses; RADIATION injuries; RADIOTHERAPY; SKIN inflammation; TREATMENT effectiveness; EVALUATION
- Publication
Breast Journal, 2020, Vol 26, Issue 2, p227
- ISSN
1075-122X
- Publication type
Article
- DOI
10.1111/tbj.13544