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- Title
What a 'Ku'incidence!: parallel discoveries of a new DNA repair factor.
- Authors
Mistrik, M; Bartek, J
- Abstract
The article discusses studies on the discovery and characterization of the non-homologous end joining (NHEJ) DNA repair factor called XLS or c9orf142. It mentions the study by A. Craxton et al. which has shown the important role of this DNA repair protein. The study by T. Ochi et al. found c9orf142 as NHEJ protein through application of bioinformatics, and the study by M. Xing et al. which associated the PAXX for the c9orf142 factor in promoting NHEJ core complex assembly under DNA damage.
- Subjects
DNA repair; DNA ligases; DNA damage; BIOINFORMATICS; BIOCHEMICAL genetics
- Publication
Cell Death & Differentiation, 2015, Vol 22, Issue 6, p888
- ISSN
1350-9047
- Publication type
Article
- DOI
10.1038/cdd.2015.32