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- Title
Clinical Outcome after Everolimus-Eluting Stent Implantation for Small Vessel Coronary Artery Disease: XIENCE Asia Small Vessel Study.
- Authors
Doo Sun Sim; Dae Young Hyun; Young Joon Hong; Ju Han Kim; Youngkeun Ahn; Myung Ho Jeong; Sang Rok Lee; Jei Keon Chae; Keun Ho Park; Young Youp Koh; Kyeong Ho Yun; Seok Kyu Oh; Seung Jae Joo; Sun Ho Hwang; Jong Pil Park; Jay Young Rhew; Su Hyun Kim; Jang Hyun Cho; Seung Uk Lee; Dong Goo Kang
- Abstract
There are limited data on outcomes after implantation of everolimus-eluting stents (EES) in East Asian patients with small vessel coronary lesions. A total of 1,600 patients treated with XIENCE EES (Abbott Vascular, CA, USA) were divided into the small vessel group treated with one =2.5 mm stent (n=119) and the non-small vessel group treated with one =2.75 mm stent (n=933). The primary end point was a patient-oriented composite outcome (POCO), a composite of all-cause death, myocardial infarction (MI), and any repeat revascularization at 12 months. The key secondary end point was a device-oriented composite outcome (DOCO), a composite of cardiovascular death, target-vessel MI, and target lesion revascularization at 12 months. The small vessel group was more often female, hypertensive, less likely to present with ST-elevation MI, and more often treated for the left circumflex artery, whereas the non-small vessel group more often had type B2/C lesions, underwent intravascular ultrasound, and received unfractionated heparin. In the propensity matched cohort, the mean stent diameter was 2.5±0.0 mm and 3.1±0.4 mm in the small and non-small vessel groups, respectively. Propensity-adjusted POCO at 12 months was 6.0% in the small vessel group and 4.3% in the non-small vessel group (p=0.558). There was no significant difference in DOCO at 12 months (small vessel group: 4.3% and non-small vessel group: 1.7%, p=0.270). Outcomes of XIENCE EES for small vessel disease were comparable to those for non-small vessel disease at 12-month clinical follow-up in real-world Korean patients.
- Subjects
MYOCARDIAL infarction; CORONARY artery disease; CORONARY arteries; EAST Asians; INTRAVASCULAR ultrasonography; KOREANS
- Publication
Chonnam Medical Journal, 2024, Vol 60, Issue 1, p78
- ISSN
2233-7385
- Publication type
Article
- DOI
10.4068/cmj.2024.60.1.78