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- Title
Versatile iron-vitamin K3 derivative-based nanoscale coordination polymer augments tumor ferroptotic therapy.
- Authors
Zhang, Zhicheng; Ding, Yawen; Li, Jinbiao; Wang, Li; Xin, Xiaoyan; Yan, Jing; Wu, Jinhui; Yuan, Ahu; Hu, Yiqiao
- Abstract
Ferroptosis is a newly form of regulated cell death, which has attracted great attention for tumor therapy. Herein, we prepared nanoscale coordination polymer Fe-NQA particles to deliver iron and NQA (vitamin K3 derivative) into tumor cells, which synergistically promoted ferroptotic therapy for inhibiting tumor growth, preventing metastasis, and overcoming radioresistance.
- Publication
Nano Research, 2021, Vol 14, Issue 7, p2398
- ISSN
1998-0124
- Publication type
Article
- DOI
10.1007/s12274-020-3241-7