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- Title
Herpes simplex and Epstein-Barr virus lymphadenitis in a patient with chronic lymphocytic leukemia treated with fludarabine.
- Authors
Mercadal, Santiago; Martinez, Antonio; Nomdedeu, Benet; Rozman, María; Gaya, Anna; Salamero, Olga; Campo, Elías
- Abstract
Multiple herpes virus co-infection is a very rare complication in patients with chronic lymphocytic leukemia (CLL). We describe a patient with a CLL who developed an herpes virus lymphadenitis. Inmunohistochemical study was positive for HSV-1, HSV-2, and Epstein-Barr Virus (EBV). The coinfection of EBV with a profile of expresion of viral latent genes type III, is usually seen in inmunodepressed patients. To the best of our knowledge, this is the first reported case of a multiple human herpes virus infection mimicking Richter syndrome.
- Subjects
HEMATOLOGY; HERPESVIRUS diseases; CHRONIC lymphocytic leukemia; LYMPHADENITIS; EPSTEIN-Barr virus
- Publication
European Journal of Haematology, 2006, Vol 77, Issue 5, p442
- ISSN
0902-4441
- Publication type
Article
- DOI
10.1111/j.1600-0609.2006.00738.x