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- Title
Immunohistochemical study of c-erb B-2 protein expression in endometriosis.
- Authors
Nasu, K; Hayata, T; Takai, N; Kawano, Y; Sugano, T; Matsui, N; Miyakawa, I
- Abstract
Using immunohistochemical techniques, we studied the expression of c-erb B-2 in normal human endometrial tissue (n = 8), endometriosis interna (adenomyosis) (n = 8) and endometriosis externa (endometriotic cyst of the ovary) (n = 6). The glandular epithelium of normal endometrial tissue specimens in the proliferative phase stained positively. Most of the cases of endometriosis studied showed no expression of c-erb B-2 in glandular epithelium. No expression was detected in either the normal or endometriotic stromal cells. Results suggest that c-erb B-2 is not significantly involved in the pathogenesis of endometriosis.
- Subjects
CELL receptors; ENDOMETRIOSIS; ENDOMETRIUM; IMMUNOHISTOCHEMISTRY; MEMBRANE proteins
- Publication
Human Reproduction, 1995, Vol 10, Issue 4, p935
- ISSN
0268-1161
- Publication type
journal article