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- Title
Economic Impact of a Rotavirus Vaccine in Brazil.
- Authors
Constenla, Dagna O.; Linhares, Alexandre C.; Rheingans, Richard D.; Antil, Lynn R.; Wladman, Eliseu A.; Da Silva, Luiz J.
- Abstract
The study was done to evaluate the cost-effectiveness of a national rotavirus vaccination programme in Brazilian children from the healthcare system perspective. A hypothetical annual birth-cohort was followed for a five-year period. Published and national administrative data were incorporated into a model to quantify the consequences of vaccination versus no vaccination. Main outcome measures included the reduction in disease burden, lives saved, and disability-adjusted life-years (DALYs) averted. A rotavirus vaccination programme in Brazil would prevent an estimated 1,804 deaths associated with gastroenteritis due to rotavirus, 91,127 hospitalizations, and 550,198 outpatient visits. Vaccination is likely to reduce 76% of the overall healthcare burden of rotavirus-associated gastroenteritis in Brazil. At a vaccine price of US$ 7-8 per dose, the cost-effectiveness ratio would be US$ 643 per DALY averted. Rotavirus vaccination can reduce the burden of gastroenteritis due to rotavirus at a reasonable cost-effectiveness ratio.
- Subjects
BRAZIL; ROTAVIRUS vaccines; ECONOMIC impact; VACCINATION of children; CHILDREN; GASTROENTERITIS; COST effectiveness
- Publication
Journal of Health, Population & Nutrition, 2008, Vol 26, Issue 4, p388
- ISSN
1606-0997
- Publication type
Article