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- Title
Anticoronavirus and Immunomodulatory Phenolic Compounds: Opportunities and Pharmacotherapeutic Perspectives.
- Authors
Dejani, Naiara Naiana; Elshabrawy, Hatem A.; Bezerra Filho, Carlos da Silva Maia; de Sousa, Damião Pergentino
- Abstract
In 2019, COVID-19 emerged as a severe respiratory disease that is caused by the novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). The disease has been associated with high mortality rate, especially in patients with comorbidities such as diabetes, cardiovascular and kidney diseases. This could be attributed to dysregulated immune responses and severe systemic inflammation in COVID-19 patients. The use of effective antiviral drugs against SARS-CoV-2 and modulation of the immune responses could be a potential therapeutic strategy for COVID-19. Studies have shown that natural phenolic compounds have several pharmacological properties, including anticoronavirus and immunomodulatory activities. Therefore, this review discusses the dual action of these natural products from the perspective of applicability at COVID-19.
- Subjects
SARS-CoV-2; COVID-19; PHENOLS; MIDDLE East respiratory syndrome
- Publication
Biomolecules (2218-273X), 2021, Vol 11, Issue 8, p1254
- ISSN
2218-273X
- Publication type
Article
- DOI
10.3390/biom11081254