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The effect of complementary and alternative medicines on CYP3A4-mediated metabolism of three different substrates: 7-benzyloxy-4-trifluoromethyl-coumarin, midazolam and docetaxel.
- Published in:
- Journal of Pharmacy & Pharmacology, 2014, v. 66, n. 6, p. 865, doi. 10.1111/jphp.12208
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- Article
Use of dried blood spots for the determination of plasma concentrations of nevirapine and efavirenz.
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- Journal of Antimicrobial Chemotherapy (JAC), 2012, v. 67, n. 5, p. 1211, doi. 10.1093/jac/dks011
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- Publication type:
- Article
No relation between docetaxel administration route and high‐grade diarrhea incidence.
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- Pharmacology Research & Perspectives, 2020, v. 8, n. 4, p. 1, doi. 10.1002/prp2.633
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- Publication type:
- Article
A Phase 1 Dose‐Escalation Study of Low‐Dose Metronomic Treatment With Novel Oral Paclitaxel Formulations in Combination With Ritonavir in Patients With Advanced Solid Tumors.
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- Clinical Pharmacology in Drug Development, 2021, v. 10, n. 6, p. 607, doi. 10.1002/cpdd.880
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- Article
Stable Isotopically Labeled Intravenous Microdose Pharmacokinetic Trials as a Tool to Assess Absolute Bioavailability: Feasibility and Paradigm to Apply for Protein Kinase Inhibitors in Oncology.
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- Clinical Pharmacology in Drug Development, 2020, v. 9, n. 5, p. 552, doi. 10.1002/cpdd.840
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- Publication type:
- Article
Effect of Food on the Pharmacokinetics of the Oral Docetaxel Tablet Formulation ModraDoc006 Combined with Ritonavir (ModraDoc006/r) in Patients with Advanced Solid Tumours.
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- Drugs in R&D, 2021, v. 21, n. 1, p. 103, doi. 10.1007/s40268-020-00336-x
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- Article
Combining Isotopic Tracer Techniques to Increase Efficiency of Clinical Pharmacokinetic Trials in Oncology.
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- Drugs in R&D, 2020, v. 20, n. 2, p. 147, doi. 10.1007/s40268-020-00304-5
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- Publication type:
- Article
Pharmacokinetics and Excretion of C-Bendamustine in Patients with Relapsed or Refractory Malignancy.
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- Drugs in R&D, 2013, v. 13, n. 1, p. 17, doi. 10.1007/s40268-012-0001-5
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- Article
Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism.
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- 2007
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- Publication type:
- journal article
Overestimation of the effect of (fos)aprepitant on intravenous dexamethasone pharmacokinetics requires adaptation of the guidelines for children with chemotherapy-induced nausea and vomiting.
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- Supportive Care in Cancer, 2022, v. 30, n. 12, p. 9991, doi. 10.1007/s00520-022-07423-6
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- Publication type:
- Article
A less sensitive detector does not necessarily result in a less sensitive method: fast quantification of 13 antiretroviral analytes in plasma with liquid chromatography coupled with tandem mass spectrometry.
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- Clinical Chemistry & Laboratory Medicine, 2010, v. 48, n. 8, p. 1153, doi. 10.1515/CCLM.2010.225
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- Publication type:
- Article
Cytoreductive Surgery and Intraoperative Hyperthermic Intraperitoneal Chemotherapy with Paclitaxel: A Clinical and Pharmacokinetic Study.
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- Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2008, v. 15, n. 4, p. 1183, doi. 10.1245/s10434-007-9792-y
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- Publication type:
- Article
Cortisol as Biomarker for CYP17-Inhibition is Associated with Therapy Outcome of Abiraterone Acetate.
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- Pharmaceutical Research, 2023, v. 40, n. 12, p. 3001, doi. 10.1007/s11095-023-03615-9
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- Publication type:
- Article
Phase I pharmacological study of continuous chronomodulated capecitabine treatment.
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- Pharmaceutical Research, 2020, v. 37, n. 5, p. 1, doi. 10.1007/s11095-020-02828-6
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- Publication type:
- Article
A simple extemporaneous oral suspension of aprepitant yields sufficient pharmacokinetic exposure in children.
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- Journal of Oncology Pharmacy Practice, 2023, v. 29, n. 4, p. 899, doi. 10.1177/10781552221089243
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- Publication type:
- Article
Urinary excretion of paclitaxel and metabolites in a large series of study.
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- Journal of Oncology Pharmacy Practice, 1998, v. 4, n. 3, p. 159, doi. 10.1177/107815529800400304
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- Publication type:
- Article
Protein versus DNA as a marker for peripheral blood mononuclear cell counting.
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- Analytical & Bioanalytical Chemistry, 2009, v. 395, n. 3, p. 863, doi. 10.1007/s00216-009-3022-3
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- Publication type:
- Article
Application of dried blood spots combined with high-performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry for simultaneous quantification of vincristine and actinomycin-D.
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- Analytical & Bioanalytical Chemistry, 2009, v. 394, n. 4, p. 1171, doi. 10.1007/s00216-009-2775-z
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- Publication type:
- Article
Mass balance and metabolite profiling of 14C-guadecitabine in patients with advanced cancer.
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- Investigational New Drugs, 2020, v. 38, n. 4, p. 1085, doi. 10.1007/s10637-019-00854-9
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- Publication type:
- Article
Pharmacokinetics and excretion of C-omacetaxine in patients with advanced solid tumors.
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- Investigational New Drugs, 2016, v. 34, n. 5, p. 565, doi. 10.1007/s10637-016-0360-9
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- Publication type:
- Article
Metabolite profiling of the multiple tyrosine kinase inhibitor lenvatinib: a cross-species comparison.
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- Investigational New Drugs, 2016, v. 34, n. 3, p. 300, doi. 10.1007/s10637-016-0342-y
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- Publication type:
- Article
Pharmacokinetics and excretion of C-lenvatinib in patients with advanced solid tumors or lymphomas.
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- Investigational New Drugs, 2015, v. 33, n. 1, p. 233, doi. 10.1007/s10637-014-0181-7
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- Publication type:
- Article
Mass spectrometry in the quantitative analysis of therapeutic intracellular nucleotide analogs.
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- Mass Spectrometry Reviews, 2011, v. 30, n. 2, p. 321, doi. 10.1002/mas.20280
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- Article
Liquid chromatography-mass spectrometry for the quantitative bioanalysis of anticancer drugs.
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- Mass Spectrometry Reviews, 2005, v. 24, n. 6, p. 887, doi. 10.1002/mas.20046
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- Publication type:
- Article
Quantitative analysis of EO9 (apaziquone) and its metabolite EO5a in human plasma by high-performance liquid chromatography under basic conditions coupled to electrospray tandem mass spectrometry.
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- Journal of Mass Spectrometry, 2006, v. 41, n. 10, p. 1268, doi. 10.1002/jms.1086
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- Publication type:
- Article
Quantitative analysis of the P-glycoprotein inhibitor Elacridar (GF120918) in human and dog plasma using liquid chromatography with tandem mass spectrometric detection.
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- Journal of Mass Spectrometry, 2004, v. 39, n. 10, p. 1122, doi. 10.1002/jms.687
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- Publication type:
- Article
Simultaneous quantification of cyclophosphamide, 4-hydroxycyclophosphamide, N,N<sup>'</sup>,N<sup>"</sup>-triethylenethiophosphoramide (thiotepa) and N,N<sup>'</sup>,N<sup>"</sup>-triethylenephosphoramide (tepa) in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry
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- Journal of Mass Spectrometry, 2004, v. 39, n. 3, p. 262
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- Publication type:
- Article
Population pharmacokinetic and adverse event analysis of topotecan in patients with solid tumors.
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- Clinical Pharmacology & Therapeutics, 2002, v. 71, n. 5, p. 334, doi. 10.1067/mcp.2002.123553
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- Publication type:
- Article
Impact of loperamide on the pharmacokinetics and tissue disposition of ritonavir-boosted oral docetaxel therapy; a preclinical assessment.
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- Cancer Chemotherapy & Pharmacology, 2024, v. 94, n. 1, p. 79, doi. 10.1007/s00280-024-04662-8
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- Publication type:
- Article
IHC-based Ki67 as response biomarker to tamoxifen in breast cancer window trials enrolling premenopausal women.
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- NPJ Breast Cancer, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41523-021-00344-3
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- Article
Therapeutic drug monitoring of small molecule kinase inhibitors in oncology in a real‐world cohort study: does age matter?
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- British Journal of Clinical Pharmacology, 2018, v. 84, n. 12, p. 2770, doi. 10.1111/bcp.13725
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- Article
Food‐effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers.
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- British Journal of Clinical Pharmacology, 2018, v. 84, n. 12, p. 2761, doi. 10.1111/bcp.13719
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- Article
Intracellular pharmacokinetics of gemcitabine, its deaminated metabolite 2′,2′‐difluorodeoxyuridine and their nucleotides.
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- British Journal of Clinical Pharmacology, 2018, v. 84, n. 6, p. 1279, doi. 10.1111/bcp.13557
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- Article
Pronounced between-subject and circadian variability in thymidylate synthase and dihydropyrimidine dehydrogenase enzyme activity in human volunteers.
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- British Journal of Clinical Pharmacology, 2016, v. 82, n. 3, p. 706, doi. 10.1111/bcp.13007
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- Publication type:
- Article
Exploring the intracellular pharmacokinetics of the 5-fluorouracil nucleotides during capecitabine treatment.
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- British Journal of Clinical Pharmacology, 2016, v. 81, n. 5, p. 949, doi. 10.1111/bcp.12877
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- Article
The effect of Echinacea purpurea on the pharmacokinetics of docetaxel.
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- British Journal of Clinical Pharmacology, 2013, v. 76, n. 3, p. 467, doi. 10.1111/bcp.12159
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- Publication type:
- Article
Intra-Tumoral Pharmacokinetics of Pazopanib in Combination with Radiotherapy in Patients with Non-Metastatic Soft-Tissue Sarcoma.
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- Cancers, 2021, v. 13, n. 22, p. 5780, doi. 10.3390/cancers13225780
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- Article
Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors.
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- 2017
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- Publication type:
- journal article
Review of Chromatographic Bioanalytical Assays for the Quantitative Determination of Marine-Derived Drugs for Cancer Treatment.
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- Marine Drugs, 2018, v. 16, n. 7, p. 246, doi. 10.3390/md16070246
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- Publication type:
- Article
Human metabolism of [14C]indisulam following i.v. infusion in cancer patients.
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- Investigational New Drugs, 2005, v. 23, n. 4, p. 317, doi. 10.1007/s10637-005-1440-4
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- Publication type:
- Article
A more sensitive MS detector does not obviously lead to a more sensitive assay: experiences with ES-285.
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- Biomedical Chromatography, 2004, v. 18, n. 6, p. 403, doi. 10.1002/bmc.404
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- Publication type:
- Article
Determination of the absolute bioavailability of oral imatinib using a stable isotopically labeled intravenous imatinib-d8 microdose.
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- European Journal of Clinical Pharmacology, 2020, v. 76, n. 8, p. 1075, doi. 10.1007/s00228-020-02888-y
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- Publication type:
- Article
Lysophospholipids secreted by splenic macrophages induce chemotherapy resistance via interference with the DNA damage response.
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- Nature Communications, 2014, v. 5, n. 11, p. 5275, doi. 10.1038/ncomms6275
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- Publication type:
- Article
Simultaneous quantification of 2′,2′-difluorodeoxycytidine and 2′,2′-difluorodeoxyuridine nucleosides and nucleotides in white blood cells using porous graphitic carbon chromatography coupled with tandem mass spectrometry.
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- Rapid Communications in Mass Spectrometry: RCM, 2009, v. 23, n. 19, p. 3040, doi. 10.1002/rcm.4212
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- Publication type:
- Article
Validated assay for the simultaneous quantification of total vincristine and actinomycin-D concentrations in human EDTA plasma and of vincristine concentrations in human plasma ultrafiltrate by high-performance liquid chromatography coupled with tandem mass spectrometry
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- Rapid Communications in Mass Spectrometry: RCM, 2009, v. 23, n. 6, p. 763, doi. 10.1002/rcm.3938
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- Publication type:
- Article
Enhanced resolution triple-quadrupole mass spectrometry for ultra-sensitive and quantitative analysis of the investigational anticancer agent EO9 (apaziquone) and its metabolite EO5a in human and dog plasma to support (pre)-clinical studies of EOquin® given intravesically
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- Rapid Communications in Mass Spectrometry: RCM, 2008, v. 22, n. 4, p. 462, doi. 10.1002/rcm.3387
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- Publication type:
- Article
Development and validation of an assay for the quantitative determination of cladribine nucleotides in MDCKII cells and culture medium using weak anion-exchange liquid chromatography coupled with tandem mass spectrometry.
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- Rapid Communications in Mass Spectrometry: RCM, 2007, v. 21, n. 24, p. 4049, doi. 10.1002/rcm.3318
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- Publication type:
- Article
Fast and simultaneous determination of darunavir and eleven other antiretroviral drugs for therapeutic drug monitoring: method development and validation for the determination of all currently approved HIV protease inhibitors and non-nucleoside reverse transcriptase inhibitors in human plasma by liquid chromatography coupled with electrospray ionization tandem mass spectrometry
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- Rapid Communications in Mass Spectrometry: RCM, 2007, v. 21, n. 15, p. 2505, doi. 10.1002/rcm.3119
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- Publication type:
- Article
Validated assay for the simultaneous determination of the anti-cancer agent gemcitabine and its metabolite 2′,2′-difluorodeoxyuridine in human plasma by high-performance liquid chromatography with tandem mass spectrometry.
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- Rapid Communications in Mass Spectrometry: RCM, 2007, v. 21, n. 14, p. 2312, doi. 10.1002/rcm.3096
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- Publication type:
- Article
Determination of ruthenium originating from the investigational anti-cancer drug NAMI-A in human plasma ultrafiltrate, plasma, and urine by inductively coupled plasma mass spectrometry.
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- Rapid Communications in Mass Spectrometry: RCM, 2007, v. 21, n. 9, p. 1521, doi. 10.1002/rcm.2985
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- Publication type:
- Article