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- Title
Risk Factors Associated with Mortality of COPD Patients Hospitalised for Exacerbation.
- Authors
Yelda Niksarlıoğlu, Elif; Ergan Arsava, Begüm; Demir, Ahmet Uğur; Topeli İskit, Arzu; Çöplü, Lütfi
- Abstract
OBJECTIVE: To investigate factors associated with mortality and assess the changes in arterial blood gas (ABG) in patients hospitalised for exacerbation of chronic obstructive pulmonary disease (COPD). MATERIAL AND METHODS: This was a retrospective analysis of 49 patients (38 men and 11 women) hospitalised in a tertiary care facility for exacerbation of COPD between January 2004 and December 2005. Data on exposures, ABG, blood chemistry, severity of COPD and treatments were collected from patient charts. Survival status was determined by hospital records and telephone contact with the patients or family members. RESULTS: The average age of patients in the study was 71.1 ±10.9 years (mean±SD), and the majority were in stage IV (25 cases, 51%) or stage III (15 cases, 30.6%). Comorbidity was reported in 42 cases (85.7%). The median duration of hospital stay was 14.8 days (range: 4-70) days. Ten patients (20.4%) received mechanical ventilation (MV) support. Six male and three female patients died (18.4%); 2 in the hospital (4.1%) and 7 during the 2 year follow-up (14.9%). Mortality was associated with older age (79.7±12.0 vs. 69.2±9.4 years) and MV support (4/9 deceased vs. 6/40 alive). The change in PaCO2 between the first measurement on admission and during hospitalisation was associated with mortality after discharge (median and range, mmHg, alive: 3 (-29-55.8) and -6 (-10.2-0.1). CONCLUSION: Prospective studies are required to test the predictive value of changes in PaCO2 for the survival in patients hospitalised for exacerbation of COPD.
- Subjects
HEART disease diagnosis; SMOKING; ADRENOCORTICAL hormones; ANTIBIOTICS; BIOTIC communities; BLOOD gases analysis; CHEST diseases; CONFIDENCE intervals; CREATININE; DIABETES; FEVER; HEMATOCRIT; HEMOGLOBINS; HOSPITAL care; LENGTH of stay in hospitals; HYPERTENSION; LYMPHOCYTES; OBSTRUCTIVE lung diseases; PROTEINS; SURVIVAL; COMORBIDITY; DATA analysis; ALBUMINS; RETROSPECTIVE studies; DISEASE exacerbation; DESCRIPTIVE statistics; BLOOD urea nitrogen; TERTIARY care; DISEASE risk factors
- Publication
Turkish Thoracic Journal / Turk Toraks Dergisi, 2013, Vol 14, Issue 4, p134
- ISSN
2149-2530
- Publication type
Article
- DOI
10.5152/ttd.2013.26