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- Title
Tissue Doppler imaging predicts left ventricular dysfunction and mortality in a murine model of cardiac injury.
- Authors
Neilan, Tomas G.; Jassal, Davinder S.; Perez-Sanz, Teresa M.; Raher, Michael J.; Pradhan, Aruna D.; Buys, Emmanuel S.; Ichinose, Fumito; Bayne, David B.; Halpern, Elkan F.; Weyman, Arthur E.; Derumeaux, Geneviéve; Bloch, Kenneth D.; Picard, Michael H.; Scherrer-Crosbie, Marielle
- Abstract
Aims Currently available non-invasive imaging methods frequently fail to detect alterations in left ventricular (LV) function despite histological evidence of injury. Tissue Doppler imaging (TDI) can detect subtle LV dysfunction. The aim of this study was to investigate whether TDI indices can predict LV systolic dysfunction and mortality following exposure to doxorubicin (DOX) in mice.
- Publication
European Heart Journal, 2006, Vol 27, Issue 15, p1868
- ISSN
0195-668X
- Publication type
Article
- DOI
10.1093/eurheartj/ehl013