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Pharmacokinetics and safety of daptomycin administered subcutaneously in healthy volunteers: a single-blinded randomized crossover trial.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 11, p. 3016, doi. 10.1093/jac/dkae324
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- Publication type:
- Article
The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia.
- Published in:
- Pharmaceutics, 2021, v. 13, n. 5, p. 601, doi. 10.3390/pharmaceutics13050601
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- Publication type:
- Article
Bayesian framework for multi-source data integration-Application to human extrapolation from preclinical studies.
- Published in:
- Statistical Methods in Medical Research, 2024, v. 33, n. 4, p. 574, doi. 10.1177/09622802241231493
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- Publication type:
- Article
Unified approach for extrapolation and bridging of adult information in early-phase dose-finding paediatric studies.
- Published in:
- 2018
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- Publication type:
- journal article
Cerebral uptake of mefloquine enantiomers with and without the P-gp inhibitor elacridar (GF1210918) in mice.
- Published in:
- British Journal of Pharmacology, 2004, v. 141, n. 7, p. 1214, doi. 10.1038/sj.bjp.0705721
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- Publication type:
- Article
Conditional Non-parametric Bootstrap for Non-linear Mixed Effect Models.
- Published in:
- Pharmaceutical Research, 2021, v. 38, n. 6, p. 1057, doi. 10.1007/s11095-021-03052-6
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- Publication type:
- Article
Variations of hepcidin and iron-status parameters during the menstrual cycle in healthy women.
- Published in:
- British Journal of Haematology, 2016, v. 175, n. 5, p. 980, doi. 10.1111/bjh.13906
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- Publication type:
- Article
Prediction of Individual Disease Progression Including Parameter Uncertainty in Rare Neurodegenerative Diseases: The Example of Autosomal-Recessive Spastic Ataxia Charlevoix Saguenay (ARSACS).
- Published in:
- AAPS Journal, 2024, v. 26, n. 3, p. 1, doi. 10.1208/s12248-024-00925-7
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- Publication type:
- Article
Correction: Uncertainty Computation at Finite Distance in Nonlinear Mixed Effects Models—a New Method Based on Metropolis–Hastings Algorithm.
- Published in:
- 2024
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- Publication type:
- Correction Notice
Correction: Prediction of Individual Disease Progression Including Parameter Uncertainty in Rare Neurodegenerative Diseases: The Example of Autosomal-Recessive Spastic Ataxia Charlevoix Saguenay (ARSACS).
- Published in:
- 2024
- By:
- Publication type:
- Correction Notice
Uncertainty Computation at Finite Distance in Nonlinear Mixed Effects Models—a New Method Based on Metropolis-Hastings Algorithm.
- Published in:
- AAPS Journal, 2024, v. 26, n. 3, p. 1, doi. 10.1208/s12248-024-00905-x
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- Publication type:
- Article
Developing Tools to Evaluate Non-linear Mixed Effect Models: 20 Years on the npde Adventure.
- Published in:
- AAPS Journal, 2021, v. 23, n. 4, p. 1, doi. 10.1208/s12248-021-00597-7
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- Publication type:
- Article
Application of Item Response Theory to Model Disease Progression and Agomelatine Effect in Patients with Major Depressive Disorder.
- Published in:
- AAPS Journal, 2020, v. 22, n. 1, p. 1, doi. 10.1208/s12248-019-0379-x
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- Publication type:
- Article
Population Pharmacokinetic-Pharmacodynamic Model of Oral Fludrocortisone and Intravenous Hydrocortisone in Healthy Volunteers.
- Published in:
- AAPS Journal, 2017, v. 19, n. 3, p. 727, doi. 10.1208/s12248-016-0041-9
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- Publication type:
- Article
Joint Model of Iron and Hepcidin During the Menstrual Cycle in Healthy Women.
- Published in:
- AAPS Journal, 2016, v. 18, n. 2, p. 490, doi. 10.1208/s12248-016-9875-4
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- Publication type:
- Article
Comparison of Nonlinear Mixed Effects Models and Noncompartmental Approaches in Detecting Pharmacogenetic Covariates.
- Published in:
- AAPS Journal, 2015, v. 17, n. 3, p. 597, doi. 10.1208/s12248-015-9726-8
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- Publication type:
- Article
Development of a Complex Parent-Metabolite Joint Population Pharmacokinetic Model.
- Published in:
- AAPS Journal, 2011, v. 13, n. 3, p. 390, doi. 10.1208/s12248-011-9282-9
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- Publication type:
- Article
Some Alternatives to Asymptotic Tests for the Analysis of Pharmacogenetic Data Using Nonlinear Mixed Effects Models.
- Published in:
- Biometrics, 2012, v. 68, n. 1, p. 146, doi. 10.1111/j.1541-0420.2011.01665.x
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- Publication type:
- Article
Recent advances in methodology for clinical trials in small populations: the InSPiRe project.
- Published in:
- 2018
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- Publication type:
- journal article
Population pharmacodynamic analysis of octreotide in acromegalic patients<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2003, v. 73, n. 1, p. 95, doi. 10.1067/mcp.2003.6
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- Publication type:
- Article
Population pharmacokinetic-pharmacodynamic analysis of fluindione in patients<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 1998, v. 63, n. 1, p. 64, doi. 10.1016/S0009-9236(98)90122-9
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- Publication type:
- Article
Dose-finding methods for Phase I clinical trials using pharmacokinetics in small populations.
- Published in:
- Biometrical Journal, 2017, v. 59, n. 4, p. 804, doi. 10.1002/bimj.201600084
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- Publication type:
- Article
Therapeutic drug monitoring and virological response at week 48 in a cohort of HIV‐1‐infected patients switching to dolutegravir/rilpivirine dual maintenance therapy (ANRS‐MIE‐BIRIDER study).
- Published in:
- British Journal of Clinical Pharmacology, 2024, v. 90, n. 1, p. 264, doi. 10.1111/bcp.15890
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- Publication type:
- Article
Population pharmacokinetics of oxcarbazepine and its monohydroxy derivative in epileptic children.
- Published in:
- British Journal of Clinical Pharmacology, 2017, v. 83, n. 12, p. 2695, doi. 10.1111/bcp.13392
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- Publication type:
- Article
A mechanism-based model for the population pharmacokinetics of free and bound aflibercept in healthy subjects.
- Published in:
- British Journal of Clinical Pharmacology, 2011, v. 72, n. 3, p. 402, doi. 10.1111/j.1365-2125.2011.04015.x
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- Publication type:
- Article
A comparison of bootstrap approaches for estimating uncertainty of parameters in linear mixed-effects models A comparison of bootstrap approaches for estimating uncertainty of parameters in linear mixed-effects models.
- Published in:
- Pharmaceutical Statistics, 2013, v. 12, n. 3, p. 129, doi. 10.1002/pst.1561
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- Publication type:
- Article
Modelling the influence of MDR1 polymorphism on digoxin pharmacokinetic parameters.
- Published in:
- European Journal of Clinical Pharmacology, 2007, v. 63, n. 5, p. 437, doi. 10.1007/s00228-007-0269-5
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- Publication type:
- Article
Population pharmacokinetic analysis of free and bound aflibercept in patients with advanced solid tumors.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2013, v. 72, n. 1, p. 167, doi. 10.1007/s00280-013-2182-1
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- Publication type:
- Article
Pharmacokinetics and neutrophil toxicity of paclitaxel orally administered in mice with recombinant interleukin-2.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2005, v. 55, n. 1, p. 61, doi. 10.1007/s00280-004-0824-z
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- Publication type:
- Article
Joint modeling of tumor dynamics and progression‐free survival in advanced breast cancer: Leveraging data from amcenestrant early phase I–II trials.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 6, p. 941, doi. 10.1002/psp4.13128
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- Publication type:
- Article
Timing of Antiviral Treatment Initiation is Critical to Reduce SARS‐CoV‐2 Viral Load.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 9, p. 509, doi. 10.1002/psp4.12543
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- Publication type:
- Article
The Standard Output: A Tool‐Agnostic Modeling Storage Format.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2018, v. 7, n. 9, p. 543, doi. 10.1002/psp4.12339
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- Publication type:
- Article
Model Description Language (MDL): A Standard for Modeling and Simulation.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2017, v. 6, n. 10, p. 647, doi. 10.1002/psp4.12222
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- Publication type:
- Article
A Survey of the Way Pharmacokinetics are Reported in Published Phase I Clinical Trials, with an Emphasis on Oncology.
- Published in:
- Clinical Pharmacokinetics, 2009, v. 48, n. 6, p. 387, doi. 10.2165/00003088-200948060-00004
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- Publication type:
- Article
Are Population Pharmacokinetic and/or Pharmacodynamic Models Adequately Evaluated?: A Survey of the Literature from 2002 to 2004.
- Published in:
- Clinical Pharmacokinetics, 2007, v. 46, n. 3, p. 221, doi. 10.2165/00003088-200746030-00003
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- Publication type:
- Article
Why Should Prediction Discrepancies Be Renamed Standardized Visual Predictive Check?
- Published in:
- 2012
- By:
- Publication type:
- Letter
Design in nonlinear mixed effects models: Optimization using the Fedorov-Wynn algorithm and power of the Wald test for binary covariates.
- Published in:
- Statistics in Medicine, 2007, v. 26, n. 28, p. 5162, doi. 10.1002/sim.2910
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- Publication type:
- Article
Impact of model misspecification on model-based tests in PK studies with parallel design: real case and simulation studies.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2022, v. 49, n. 5, p. 557, doi. 10.1007/s10928-022-09821-z
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- Publication type:
- Article
Evaluation of bootstrap methods for estimating uncertainty of parameters in nonlinear mixed-effects models: a simulation study in population pharmacokinetics.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2014, v. 41, n. 1, p. 15, doi. 10.1007/s10928-013-9343-z
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- Publication type:
- Article
Extension of NPDE for evaluation of nonlinear mixed effect models in presence of data below the quantification limit with applications to HIV dynamic model.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2012, v. 39, n. 5, p. 499, doi. 10.1007/s10928-012-9264-2
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- Publication type:
- Article
Pharmacogenetics and population pharmacokinetics: impact of the design on three tests using the SAEM algorithm.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2009, v. 36, n. 4, p. 317, doi. 10.1007/s10928-009-9124-x
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- Publication type:
- Article
Multivariate Exact Discrepancy: A New Tool for PK/PD Model Evaluation.
- Published in:
- Clinical Pharmacokinetics, 2023, v. 62, n. 11, p. 1599, doi. 10.1007/s40262-023-01296-6
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- Publication type:
- Article
A dose finding design for seizure reduction in neonates.
- Published in:
- Journal of the Royal Statistical Society: Series C (Applied Statistics), 2019, v. 68, n. 2, p. 427, doi. 10.1111/rssc.12289
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- Publication type:
- Article
Ciprofloxacin population pharmacokinetics during long-term treatment of osteoarticular infections.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Effects of Postpartum Supplemental Oral Ca for Dairy Cows Fed Prepartum Dietary Acidogenic Salts.
- Published in:
- Animals (2076-2615), 2021, v. 11, n. 11, p. 3131, doi. 10.3390/ani11113131
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- Publication type:
- Article